Results 71 to 80 of about 12,361,159 (162)
PCR Detection of B. cenocepacia
Burkholderia cenocepacia is a bacterium that is both a plant and human pathogen. It is a common cause of respiratory infection in people with cystic fibrosis. It is taxonomically grouped as a member of Burkholderia cepacia complex (Bcc). While several
Dalal, Ishita
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Burkholderia cenocepacia ET12 strain activates TNFR1 signalling in cystic fibrosis airway epithelial cells [PDF]
Burkholderia cenocepacia is an important pulmonary pathogen in individuals with cystic fibrosis (CF). Infection is often associated with severe pulmonary inflammation, and some patients develop a fatal necrotizing pneumonia and sepsis (‘cepacia syndrome’)
Sajjan, Umadevi S. +3 more
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Burkholderia cenocepacia infections are difficult to treat due to resistance, biofilm formation and persistence. B. cenocepacia strain J2315 has a large multi-replicon genome (8.06 Mb) and the function of a large fraction of (conserved) hypothetical ...
Heleen Van Acker +12 more
doaj +1 more source
Significance Statement This study provides a chloroplast‐ and mitochondrion‐specific random mutagenesis tool specialized for C‐to‐T substitutions, enabling organelle genome‐focused forward genetic analysis. By utilizing this tool, we can screen for organelle genome‐associated traits and isolate novel mutations that are not only of physiological ...
Nanami Kosaka +6 more
wiley +1 more source
Genetic similarity of Burkholderia cenocepacia from cystic fibrosis patients
Burkholderia cenocepacia may cause serious infections in patients with cystic fibrosis, and this microorganism can be highly transmissible. Pulsed-field gel electrophoresis is widely used to study the dynamics of strain spread in cystic fibrosis patients.
Luana Pretto +4 more
doaj +1 more source
Homogenous response of B. cenocepacia K56-2 to bacteriostatic antibiotics. n = 6.
Homogenous response of B. cenocepacia K56-2 to bacteriostatic antibiotics. n = 6.
Miguel A. Valvano (148588) +1 more
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ABSTRACT Waterborne diseases and antimicrobial resistance (AMR) pose mounting public health threats across sub‐Saharan Africa, particularly in rapidly urbanising regions dependent on untreated or poorly treated surface waters. This study applied shotgun metagenomic sequencing to characterise microbial communities, virulence factors and antibiotic ...
Oleg N. Reva +8 more
wiley +1 more source
Biofilm Associated Persistence and Drug Tolerance in Mycobacteria Within Host Microenvironments
ABSTRACT Biofilms formed by mycobacteria, particularly Mycobacterium tuberculosis (Mtb), represent a major challenge in tuberculosis (TB) treatment due to their highly organized structure and their capacity to induce phenotypic drug tolerance. These three‐dimensional bacterial aggregates are embedded in a self‐produced extracellular matrix that ...
Lourdes Serrano Garcia +3 more
wiley +1 more source
Heterogeneous response of B. cenocepacia to PmB.
Population analysis profiling (PAP) of B. cenocepacia strains K56-2, K56-2ΔrpoE, K56-2ΔrpoE/500, CF706-J, K56-2ΔhldA, and K56-2ΔarnBC, and P. aeruginosa PAO1 by agar dilution at 24 h except for CF706-J by broth dilution at 18 h. n = 6. Panels (B) and (C),
Miguel A. Valvano (148588) +1 more
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Genomics Reveals a Unique Clone of Burkholderia cenocepacia Harboring an Actively Excising Novel Genomic Island [PDF]
Burkholderia cenocepacia is a clinically dominant form among the other virulent species of Burkholderia cepacia complex (Bcc). In the present study, we sequenced and analyzed the genomes of seven nosocomial Bcc isolates, five of which were isolated from ...
Singhal, Lipika +17 more
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