Molecular Microbiology, 2017 SummaryLipid A anchors the lipopolysaccharide (LPS) to the outer membrane and is usually composed of a hexa‐acylated diglucosamine backbone. Burkholderia cenocepacia, an opportunistic pathogen, produces a mixture of tetra‐ and penta‐acylated lipid A. “Late” acyltransferases add secondary acyl chains to lipid A after the incorporation of four primary ...
Yasmine Fathy Mohamed +3 more
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MicrobiologyOpen, Volume 15, Issue 3, June 2026.Pseudomonas strains R32 and R47 inhibit Phytophthora infestans, which causes late blight in potato. To assess the importance of pyoverdine, a high‐affinity siderophore both strains produce, in P. infestans inhibition, we produced pyoverdine‐deficient mutants and tested their antagonistic activity at different developmental stages of the pathogen ...
Livia Jerjen +2 more
wiley +1 more source
Interaction of environmental Burkholderia cenocepacia strains with cystic fibrosis and non-cystic fibrosis bronchial epithelial cells in vitro [PDF]
Microbiology, 2012 Burkholderia cenocepacia is an important human pathogen in patients with cystic fibrosis (CF). Non-clinical reservoirs may play a role in the acquisition of infection, so it is important to evaluate the pathogenic potential of environmental B. cenocepacia isolates. In this study, we investigated the interactions of two environmental B.
Bevivino, Annamaria +7 more
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Scientific Reports, 2021 Infections by Burkholderia cenocepacia lead to life-threatening disease in immunocompromised individuals, including those living with cystic fibrosis (CF). While genetic variation in various B.
Olakunle A. Jaiyesimi +3 more
doaj +1 more source
Lung Microbiome Diversity, Infection Dynamics, and Microbe‐Mediated Cross‐Protection
MicrobiologyOpen, Volume 15, Issue 3, June 2026.The protective role of the lung microbiome in maintaining respiratory health by promoting immune homeostasis, pathogen exclusion, and barrier integrity. Diverse microbial communities regulate immune maturation, enhance epithelial defenses, and contribute to antiviral responses, collectively preventing pathogen colonization and sustaining a balanced ...
Sana Arooj +7 more
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Efflux pump genes of the resistance-nodulation-division family in
BMC Microbiology, 2006 Background Burkholderia cenocepacia is recognized as opportunistic pathogen that can cause lung infections in cystic fibrosis patients. A hallmark of B.
Manina Giulia +6 more
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Modelling co-infection of the cystic fibrosis lung by Pseudomonas aeruginosa and Burkholderia cenocepacia reveals influences on biofilm formation and host response. [PDF]
PLoS ONE, 2012 The Gram-negative bacteria Pseudomonas aeruginosa and Burkholderia cenocepacia are opportunistic human pathogens that are responsible for severe nosocomial infections in immunocompromised patients and those suffering from cystic fibrosis (CF).
Alessandra Bragonzi +9 more
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Oridonin Attenuates Burkholderia cenocepacia Virulence by Suppressing Quorum-Sensing Signaling
Microbiology Spectrum, 2022 Burkholderia cenocepacia is a human opportunistic pathogen that mostly employs two types of quorum-sensing (QS) systems to regulate its various biological functions and pathogenicity: the cis-2-dodecenoic acid (BDSF) system and the N-acyl homoserine ...
Xia Li +6 more
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GeoHealth, Volume 10, Issue 6, June 2026.Abstract Melioidosis is a potentially fatal tropical disease caused by the environmentally mediated bacterium, Burkholderia pseudomallei. In Vietnam, melioidosis is not nationally reportable and little is known regarding its epidemiology and distribution in the northernmost mountainous provinces.
Morgan C. Metrailer +14 more
wiley +1 more source
Nasal Immunization withBurkholderia multivoransOuter Membrane Proteins and the Mucosal Adjuvant Adamantylamide Dipeptide Confers Efficient Protection against Experimental Lung Infections withB. multivoransandB. cenocepacia [PDF]
Infection and Immunity, 2007 ABSTRACTChronic lung infection by opportunistic pathogens, such asPseudomonas aeruginosaand members of theBurkholderia cepaciacomplex, is a major cause of morbidity and mortality in patients with cystic fibrosis. Outer membrane proteins (OMPs) of gram-negative bacteria are promising vaccine antigen candidates.
Bertot, Gustavo M +5 more
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