Results 41 to 50 of about 12,361,159 (162)
The Small RNA ncS35 Regulates Growth in
mSphere, 2018 Burkholderia cenocepacia J2315 is a member of the B. cepacia complex. It has a large genome with three replicons and one plasmid; 7,261 genes code for annotated proteins, while 113 code for functional RNAs. Small regulatory RNAs of B.
Sanne Kiekens +4 more
doaj +1 more source
Scientific Reports, 2021 Burkholderia cenocepacia is known for its capacity of adherence and interaction with the host, causing severe opportunistic lung infections in cystic fibrosis patients.
Andreia I. Pimenta +4 more
doaj +1 more source
mSphere, 2022 Interactions between different bacterial species shape bacterial communities and their environments. The opportunistic pathogens Pseudomonas aeruginosa and Burkholderia cenocepacia both can colonize the lungs of individuals affected by cystic fibrosis ...
Charles Morin +3 more
doaj +1 more source
Strategies and mechanisms of precision genome engineering: From gene editing to genome writing
iMetaOmics, Volume 3, Issue 3, September 2026.In this review, we examined the progression of genome manipulation from stochastic nuclease‐mediated cutting toward precise editing and programmable genome writing. We discussed tools like multi‐kilobase RNA‐guided integrators and Artificial Intelligence (AI)‐designed effectors and showed how these advances enable researchers to treat genomes as ...
Kerui Huang +19 more
wiley +1 more source
Extracellular GSH decreases B. cenocepacia invasion. Panel A.
, 2012 Invasion of 9HTEo- and CFTE29o- by B. cenocepacia LMG 16656 was assayed in presence of 0, 0.1, 1 and 10 mM GSH. The % of invasion indicates the ratio between the number of intracellular bacteria recovered from infected cells with respect to the bacteria ...
Melania D’Orazio (126856) +2 more
core +1 more source
Frontiers in Microbiology, 2017 Burkholderia cenocepacia is an opportunistic pathogen particularly dangerous for cystic fibrosis (CF) patients. It can cause a severe decline in CF lung function possibly developing into a life-threatening systemic infection known as cepacia syndrome ...
Viola C. Scoffone +6 more
doaj +1 more source
Scientific Reports, 2021 Infections by Burkholderia cenocepacia lead to life-threatening disease in immunocompromised individuals, including those living with cystic fibrosis (CF). While genetic variation in various B.
Olakunle A. Jaiyesimi +3 more
doaj +1 more source
DAMPs, PAMPs, and Alarmins: From Mechanism to Therapy
MedComm, Volume 7, Issue 9, September 2026.This review synthesizes the expanding biology of PAMPs and DAMPs, from their molecular sources and sensing mechanisms to regulatory networks that govern inflammation and homeostasis. Spanning from classical immune activation to trained immunity and interorgan communication, we highlight the interplay between PAMPs and DAMPs and their context‐dependent ...
Xuanxuan Yu +6 more
wiley +1 more source
Modelling co-infection of the cystic fibrosis lung by Pseudomonas aeruginosa and Burkholderia cenocepacia reveals influences on biofilm formation and host response. [PDF]
PLoS ONE, 2012 The Gram-negative bacteria Pseudomonas aeruginosa and Burkholderia cenocepacia are opportunistic human pathogens that are responsible for severe nosocomial infections in immunocompromised patients and those suffering from cystic fibrosis (CF).
Alessandra Bragonzi +9 more
doaj +1 more source
Oridonin Attenuates Burkholderia cenocepacia Virulence by Suppressing Quorum-Sensing Signaling
Microbiology Spectrum, 2022 Burkholderia cenocepacia is a human opportunistic pathogen that mostly employs two types of quorum-sensing (QS) systems to regulate its various biological functions and pathogenicity: the cis-2-dodecenoic acid (BDSF) system and the N-acyl homoserine ...
Xia Li +6 more
doaj +1 more source