Results 21 to 30 of about 12,361,159 (162)

Inactivation of Rho GTPases by Burkholderia cenocepacia Induces a WASH-Mediated Actin Polymerization that Delays Phagosome Maturation

open access: yesCell Reports, 2020
Summary: Burkholderia cenocepacia is an opportunistic bacterial pathogen that causes severe pulmonary infections in cystic fibrosis and chronic granulomatous disease patients. B.
Glenn F.W. Walpole   +10 more
doaj   +1 more source

Phage-antibiotic synergy reduces Burkholderia cenocepacia population

open access: yesBMC Microbiology, 2023
Background Burkholderia cenocepacia is an opportunistic pathogen that can cause acute and chronic infections in patients with weakened immune systems and in patients with cystic fibrosis. B.
Anna G. Mankovich   +5 more
doaj   +1 more source

Genetic Determinants Associated With in Vivo Survival of Burkholderia cenocepacia in the Caenorhabditis elegans Model

open access: yesFrontiers in Microbiology, 2018
A Burkholderia cenocepacia infection usually leads to reduced survival and fatal cepacia syndrome in cystic fibrosis patients. The identification of B. cenocepacia essential genes for in vivo survival is key to designing new anti-infectives therapies. We
Yee-Chin Wong   +7 more
doaj   +1 more source

The exopolysaccharide gene cluster Bcam1330-Bcam1341 is involved in Burkholderia cenocepacia biofilm formation, and its expression is regulated by c-di-GMP and Bcam1349 [PDF]

open access: yes, 2013
In Burkholderia cenocepacia, the second messenger cyclic diguanosine monophosphate (c-di-GMP) has previously been shown to positively regulate biofilm formation and the expression of cellulose and type-I fimbriae genes through binding to the ...
Ryan, Robert P   +4 more
core   +1 more source

Key Players and Individualists of Cyclic-di-GMP Signaling in Burkholderia cenocepacia

open access: yesFrontiers in Microbiology, 2019
Burkholderia cenocepacia H111 is an opportunistic pathogen associated with chronic lung infections in cystic fibrosis patients. Biofilm formation, motility and virulence of B.
Anja M. Richter   +8 more
doaj   +1 more source

Burkholderia cenocepacia utilizes a type VI secretion system for bacterial competition

open access: yesMicrobiologyOpen, 2019
Burkholderia cenocepacia is an opportunistic bacterial pathogen that poses a significant threat to individuals with cystic fibrosis by provoking a strong inflammatory response within the lung.
Helena L. Spiewak   +6 more
doaj   +1 more source

Global changes in gene expression by the opportunistic pathogen Burkholderia cenocepacia in response to internalization by murine macrophages

open access: yesBMC Genomics, 2012
Background Burkholderia cenocepacia is an opportunistic pathogen causing life-threatening infections in patients with cystic fibrosis. The bacterium survives within macrophages by interfering with endocytic trafficking and delaying the maturation of the ...
Tolman Jennifer S, Valvano Miguel A
doaj   +1 more source

Interferon-gamma-activated macrophages infected with Burkholderia cenocepacia process and present bacterial antigens to T-cells by class I and II major histocompatibility complex molecules

open access: yesEmerging Microbes and Infections, 2020
Burkholderia cenocepacia is an emerging opportunistic pathogen for people with cystic fibrosis and chronic granulomatous disease. Intracellular survival in macrophages within a membrane-bound vacuole (BcCV) that delays acidification and maturation into ...
Roberto Rosales-Reyes   +10 more
doaj   +1 more source

Burkholderia cenocepacia ST-250 in cystic fibrosis patients in Switzerland: Genomic investigation of transmission routes. [PDF]

open access: yes
This report describes the characterization of Burkholderia cenocepacia isolates belonging to sequence type (ST)-250, detected in eight patients with cystic fibrosis (CF) in Switzerland. We retrospectively analyzed 18 isolates of B.
Mueller, Nicolas J   +13 more
core   +4 more sources

Identification of synergists that potentiate the action of polymyxin B against Burkholderia cenocepacia [PDF]

open access: yes, 2015
Burkholderia cenocepacia and other members of the Burkholderia cepacia complex (Bcc) are highly multidrug-resistant bacteria that cause severe pulmonary infections in patients with cystic fibrosis. A screen of 2686 compounds derived from marine organisms
Loutet, Slade A.   +7 more
core   +1 more source

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