Results 21 to 30 of about 4,634 (162)

The temperate Burkholderia phage AP3 of the Peduovirinae shows efficient antimicrobial activity against B. cenocepacia of the IIIA lineage. [PDF]

Appl Microbiol Biotechnol, 2017
Burkholderia phage AP3 (vB_BceM_AP3) is a temperate virus of the Myoviridae and the Peduovirinae subfamily (P2likevirus genus). This phage specifically infects multidrug-resistant clinical Burkholderia cenocepacia lineage IIIA strains commonly isolated from cystic fibrosis patients.
Roszniowski B, Latka A, Maciejewska B, Vandenheuvel D, Olszak T, Briers Y, Holt GS, Valvano MA, Lavigne R, Smith DL, Drulis-Kawa Z.   +10 more
europepmc   +6 more sources

Whole-Genome Sequencing of Three Clonal Clinical Isolates of B. cenocepacia from a Patient with Cystic Fibrosis. [PDF]

PLoS One, 2015
Burkholderia cepacia complex bacteria are amongst the most feared of pathogens in cystic fibrosis (CF). The BCC comprises at least 20 distinct species that can cause chronic and unpredictable lung infections in CF. Historically the species B. cenocepacia has been the most prevalent in CF infections and has been associated in some centers with high ...
Miller RR, Hird TJ, Tang P, Zlosnik JE.
europepmc   +5 more sources

DNA Methylation Epigenetically Regulates Gene Expression in Burkholderia cenocepacia and Controls Biofilm Formation, Cell Aggregation, and Motility

mSphere, 2020
Respiratory tract infections by the opportunistic pathogen Burkholderia cenocepacia often lead to severe lung damage in cystic fibrosis (CF) patients.
Ian Vandenbussche, Andrea Sass, Marta Pinto-Carbó, Olga Mannweiler, Leo Eberl, Tom Coenye   +5 more
doaj   +3 more sources

Gasdermin D restricts Burkholderia cenocepacia infection in vitro and in vivo

Scientific Reports, 2021
Burkholderia cenocepacia (B. cenocepacia) is an opportunistic bacterium; causing severe life threatening systemic infections in immunocompromised individuals including cystic fibrosis patients.
Shady Estfanous, Kathrin Krause, Midhun N. K. Anne, Mostafa Eltobgy, Kyle Caution, Arwa Abu Khweek, Kaitlin Hamilton, Asmaa Badr, Kylene Daily, Cierra Carafice, Daniel Baetzhold, Xiaoli Zhang, Tianliang Li, Haitao Wen, Mikhail A. Gavrilin, Hesham Haffez, Sameh Soror, Amal O. Amer   +17 more
doaj   +1 more source

Identification of synergists that potentiate the action of polymyxin B against Burkholderia cenocepacia [PDF]

International Journal of Antimicrobial Agents, 2015
Burkholderia cenocepacia and other members of the Burkholderia cepacia complex (BCC) are highly multidrug-resistant bacteria that cause severe pulmonary infections in patients with cystic fibrosis. A screen of 2686 compounds derived from marine organisms identified molecules that could synergise with polymyxin B (PMB) to inhibit the growth of B ...
Slade A. Loutet, Omar M. El-Halfawy, Agatha N. Jassem, José María Sánchez López, Antonio Fernández Medarde, David P. Speert, Julian E. Davies, Miguel A. Valvano   +7 more
openaire   +4 more sources

Contributions of two UDP-glucose dehydrogenases to viability and polymyxin B resistance of Burkholderia cenocepacia [PDF]

Microbiology, 2009
Burkholderia cenocepaciais highly resistant to antimicrobial peptides and we hypothesized that the conversion of UDP-glucose to UDP-glucuronic acid, a reaction catalysed by the enzyme UDP-glucose dehydrogenase (Ugd) would be important for this resistance. The genome ofB. cenocepaciacontains three predictedugdgenes:ugdBCAL2946,ugdBCAM0855andugdBCAM2034,
Loutet, Slade A, Bartholdson, S Josefin, Govan, John R W, Campopiano, Dominic J, Valvano, Miguel A   +4 more
openaire   +3 more sources

Evaluation of MALDI-TOF MS System for the Identification and Differentiation of Burkholderia cepacia Complex Species [PDF]

Brazilian Archives of Biology and Technology, 2022
To evaluate the performance of MALDI-TOF MS system as a tool for identification and differentiation of Burkholderia cenocepacia from other species of Burkholderia cepacia complex (Bcc).
Fabiana Caroline Zempulski Volpato, Mayana Kieling Hernandez, Daiana de Lima-Morales, Priscila Lamb Wink, Daniela de Souza Martins, Katia Ruschel Pilger de Oliveira, Afonso Luís Barth   +6 more
doaj   +1 more source

Antibacterial activity of a lectin‐like Burkholderia cenocepacia protein [PDF]

MicrobiologyOpen, 2013
AbstractBacteriocins of the LlpA family have previously been characterized in the γ‐proteobacteria Pseudomonas and Xanthomonas. These proteins are composed of two MMBL (monocot mannose‐binding lectin) domains, a module predominantly and abundantly found in lectins from monocot plants.
Ghequire, Maarten, De Canck, Evelien, Wattiau, Pierre, Van Winge, Iris, Loris, Remy, Coenye, Tom, De Mot, René   +6 more
openaire   +4 more sources

Salicylate induces an antibiotic efflux pump in Burkholderia cepacia complex genomovar III (B. cenocepacia) [PDF]

Journal of Clinical Investigation, 2004
An antibiotic efflux gene cluster that confers resistance to chloramphenicol, trimethoprim, and ciprofloxacin has been identified in Burkholderia cenocepacia (genomovar III), an important cystic fibrosis pathogen. Five open reading frames have been identified in the cluster. There is apparently a single transcriptional unit, with llpE encoding a lipase-
Bindu M, Nair, K-John, Cheung, Adam, Griffith, Jane L, Burns   +3 more
openaire   +2 more sources

Identification of Potential Diagnostic Markers among Burkholderia cenocepacia and B. multivorans Supernatants [PDF]

Journal of Clinical Microbiology, 2010
ABSTRACT Patients with cystic fibrosis (CF) are susceptible to chronic respiratory infections with a number of bacterial pathogens. Among them, the Burkholderia cepacia complex (Bcc) bacteria, consisting of nine related species, have emerged as problematic CF pathogens due to their antibiotic resistance ...
Tiffany, Mott, Michael, Soler, Sierrah, Grigsby, Ronald, Medley, Gregory C, Whitlock   +4 more
openaire   +2 more sources