Results 31 to 40 of about 4,634 (162)

Inactivation of Rho GTPases by Burkholderia cenocepacia Induces a WASH-Mediated Actin Polymerization that Delays Phagosome Maturation

open access: yesCell Reports, 2020
Summary: Burkholderia cenocepacia is an opportunistic bacterial pathogen that causes severe pulmonary infections in cystic fibrosis and chronic granulomatous disease patients. B.
Glenn F.W. Walpole   +10 more
doaj   +1 more source

Phage-antibiotic synergy reduces Burkholderia cenocepacia population

open access: yesBMC Microbiology, 2023
Background Burkholderia cenocepacia is an opportunistic pathogen that can cause acute and chronic infections in patients with weakened immune systems and in patients with cystic fibrosis. B.
Anna G. Mankovich   +5 more
doaj   +1 more source

Comparative Genomics and Evolutionary Analysis of RNA-Binding Proteins of Burkholderia cenocepacia J2315 and Other Members of the B. cepacia Complex [PDF]

open access: yesGenes, 2020
RNA-binding proteins (RBPs) are important regulators of cellular functions, playing critical roles on the survival of bacteria and in the case of pathogens, on their interaction with the host. RBPs are involved in transcriptional, post-transcriptional, and translational processes.
Joana R. Feliciano   +3 more
openaire   +2 more sources

Genetic Determinants Associated With in Vivo Survival of Burkholderia cenocepacia in the Caenorhabditis elegans Model

open access: yesFrontiers in Microbiology, 2018
A Burkholderia cenocepacia infection usually leads to reduced survival and fatal cepacia syndrome in cystic fibrosis patients. The identification of B. cenocepacia essential genes for in vivo survival is key to designing new anti-infectives therapies. We
Yee-Chin Wong   +7 more
doaj   +1 more source

Host evasion by Burkholderia cenocepacia

open access: yesFrontiers in Cellular and Infection Microbiology, 2012
Burkholderia cenocepacia is an opportunistic respiratory pathogen of individuals with cystic fibrosis (CF). It is one of the highly transmissible species of Burkholderia cepacia complex and very resistant to almost all the antibiotics.
Shyamala eGanesan, Umadevi S Sajjan
doaj   +1 more source

Interferon-gamma-activated macrophages infected with Burkholderia cenocepacia process and present bacterial antigens to T-cells by class I and II major histocompatibility complex molecules

open access: yesEmerging Microbes and Infections, 2020
Burkholderia cenocepacia is an emerging opportunistic pathogen for people with cystic fibrosis and chronic granulomatous disease. Intracellular survival in macrophages within a membrane-bound vacuole (BcCV) that delays acidification and maturation into ...
Roberto Rosales-Reyes   +10 more
doaj   +1 more source

Burkholderia cenocepacia utilizes a type VI secretion system for bacterial competition

open access: yesMicrobiologyOpen, 2019
Burkholderia cenocepacia is an opportunistic bacterial pathogen that poses a significant threat to individuals with cystic fibrosis by provoking a strong inflammatory response within the lung.
Helena L. Spiewak   +6 more
doaj   +1 more source

Global changes in gene expression by the opportunistic pathogen Burkholderia cenocepacia in response to internalization by murine macrophages

open access: yesBMC Genomics, 2012
Background Burkholderia cenocepacia is an opportunistic pathogen causing life-threatening infections in patients with cystic fibrosis. The bacterium survives within macrophages by interfering with endocytic trafficking and delaying the maturation of the ...
Tolman Jennifer S, Valvano Miguel A
doaj   +1 more source

New insights into the immunoproteome of B. cenocepacia J2315 using serum samples from cystic fibrosis patients

open access: yesNew Biotechnology, 2020
Bacteria of the Burkholderia cepacia complex (Bcc) are ubiquitous multidrug resistant organisms and opportunistic pathogens capable of causing life threatening lung infections among cystic fibrosis (CF) patients. No effective therapies are currently available to eradicate Bcc bacteria from CF patients, as these organisms are inherently resistant to the
Sílvia A. Sousa   +8 more
openaire   +4 more sources

Genomic analyses of Burkholderia cenocepacia reveal multiple species with differential host-adaptation to plants and humans

open access: yesBMC Genomics, 2019
Background Burkholderia cenocepacia is a human opportunistic pathogen causing devastating symptoms in patients suffering from immunodeficiency and cystic fibrosis. Out of the 303 B.
Adrian Wallner   +4 more
doaj   +1 more source

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