Molecular aspects of Bordetella pertussis pathogenesis [PDF]
, 2010 The molecular mechanisms of Bordetella virulence are now well understood, and many virulence factors have been identified and characterized at the molecular level.
Camille Locht
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Changes in the genomic content of circulating Bordetella pertussis strains isolated from the Netherlands, Sweden, Japan and Australia: adaptive evolution or drift? [PDF]
, 2010 Background Bordetella pertussis is the causative agent of human whooping cough (pertussis) and is particularly severe in infants. Despite worldwide vaccinations, whooping cough remains a public health problem.
Audrey J King +4 more
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CLINICAL CASE REPORT: PERTUSSIS INFECTION FOLLOWED BY A PARAPERTUSSIS INFECTION IN THE SAME CHILD
Problems of Infectious and Parasitic DiseasesWhooping cough is a vaccine-preventable, acute respiratory disease caused by the gram-negative bacterium Bordetella pertussis. In recent years there has been a worldwide reccurrence of pertussis infection.
Nadia Brankova +4 more
doaj +1 more source
Investigating genome reduction of Bordetella pertussis using a multiplex PCR-based reverse line blot assay (mPCR/RLB) [PDF]
, 2014 BACKGROUND: The genetic composition of the bacterium causing whooping cough, Bordetella pertussis, has been investigated using microarray studies in order to examine potential genetic contributors to the disease re-emergence in the past decade.
Connie Lam +4 more
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Influenza and Other Respiratory Viruses, Volume 19, Issue 9, September 2025.ABSTRACT Background We evaluated the effectiveness of the influenza vaccine programme against infection among emergency hospital admissions with respiratory conditions in Northern Ireland during the 2023/2024 influenza season. Methods Using a test‐negative design, we compared the odds of vaccination between patients who tested positive (cases) and ...
Magda Bucholc +2 more
wiley +1 more source
Bordetella Adenylate Cyclase-Hemolysin Toxins
Toxins, 2017 Adenylate cyclase-hemolysin toxin is secreted and produced by three classical species of the genus Bordetella: Bordetella pertussis, B. parapertussis and B. bronchiseptica.
Nicole Guiso
doaj +1 more source
The Bordetella Secreted Regulator BspR Is Translocated into the Nucleus of Host Cells via Its N-Terminal Moiety: Evaluation of Bacterial Effector Translocation by the Escherichia coli Type III Secretion System. [PDF]
PLoS ONE, 2015 Bordetella bronchiseptica is genetically related to B. pertussis and B. parapertussis, which cause respiratory tract infections in humans. These pathogens possess a large number of virulence factors, including the type III secretion system (T3SS), which ...
Akio Abe +4 more
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Construction of Minitransposons for Constitutive and Inducible Expression of Pertussis Toxin in Bvg-Negative Bordetella-Bronchiseptica [PDF]
, 1991 Appropriately detoxified pertussis toxin (PT) of Bordetella pertussis is considered to be an essential component of new-generation whooping cough vaccines, but the development of a procedure to obtain high levels of purified toxin has been and continues ...
Rohde, Manfred +3 more
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Protein Science, Volume 34, Issue 8, August 2025.Abstract The use of polyhydroxybutyrate (PHB) bioplastics has the potential to create a circular and sustainable recycling plastic system. Here, we focus on PHB degradation and characterize the multidomain PHB hydrolyzing enzyme from the extremophile Thermanaeromonas tohohensis.
Stephen Quirk +5 more
wiley +1 more source
Pediatric Transplantation, Volume 29, Issue 5, August 2025.ABSTRACT Background Hematopoietic stem cell transplantation (HSCT) in solid organ transplant recipients has been reported in adults. However, data on children are scarce. We report a case of an allogeneic HSCT in a 14‐year‐old girl to treat idiopathic very severe aplastic anemia (SAA). Case Presentation The girl developed end‐stage renal disease at the
Gintarė Mierkienė +4 more
wiley +1 more source