Results 61 to 70 of about 1,188,690 (195)
, 1987 Tumors were eradicated following adoptive immunotherapy of (C57BL/6J X DBA/2J) F1 (B6D2F1) hybrid mice bearing the C57B1/6J (B6) sarcoma, MCA/76-9, by treatment with cyclophosphamide (CY) and adoptively transferred tumor-sensitized B6D2F1 T cells ...
Evans, R, Duffy, T M
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European Journal of Neuroscience, Volume 63, Issue 12, June 2026.Myeloid cell depletion in males is rapid and initially more effective than in females, which leads to reduced occurrence of dystonia‐like neurological symptoms and alleviated neuronal loss in a mouse model of MSA. Overall, these findings indicate that the therapeutic efficacy of CSF1R‐mediated myeloid cell depletion in MSA is sex‐specific. ABSTRACT Sex‐
Kristina Battis +8 more
wiley +1 more source
Survival profile associated with sham, burn, RI and CI mice over 30 days.
, 2015 30-day survival analysis for female B6D2F1/J mice subjected to skin burn injury alone (BURN), whole-body ionizing irradiation alone (RI) or when combined with skin burn injury (CI) compared to experimental control mice (SHAM), n = 20–22 per group.
Joshua M. Swift (628430) +3 more
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Fertility & Reproduction, 2023 Background and Aims: While the histone deacetylase inhibitor Scriptaid has been reported to be effective to improve ROSI results, there are also reports that offspring born after its use are stunted.
Atsushi Tanaka +5 more
doaj +1 more source
Testicular mRNA‐LNP Delivery: A Novel Therapy for Genetic Spermatogenic Disorders
Advanced Science, Volume 13, Issue 22, 17 April 2026.In the current study, we developed a novel therapy for genetic spermatogenic disorders. It was revealed that in vivo delivery of mRNA LNP3 could restore spermatogenesis in Msh5D486Y/D486Y and Maps KO mouse models with meiotic arrest. Notably, the offspring without genomic integration was born using ICSI derived from the rescue of Msh5D486Y/D486Y mouse ...
Chenwang Zhang +22 more
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, 2015 GVHD was induced by the transfer of splenocytes from semi allogeneic C57BL/6J donors to B6D2F1 mice. Fullerol (10 mg/Kg in 100 ml of PBS, i.p.) was given to the B6D2F1 mice 30 min before transplantation and every 48 hours thereafter during the entire ...
Maurício V. B. Pinheiro (721078) +11 more
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Co-Therapy of Pegylated G-CSF and Ghrelin for Enhancing Survival After Exposure to Lethal Radiation
Frontiers in Pharmacology, 2021 Exposure to ionizing radiation (radiation injury, RI) in nuclear-related episode is evident to be life-threatening. RI occurs at levels of organs, tissues, cytosols, or nucleus. Their mechanisms are still not fully understood.
Juliann G. Kiang +7 more
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CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 4, April 2026.ABSTRACT The optimal post‐transplant cyclophosphamide (PTCy) dose to prevent graft‐versus‐host disease (GVHD) after allogeneic hematopoietic cell transplant (HCT) is undefined. Data from a novel murine HLA‐haploidentical HCT model suggested that PTCy has a dose‐dependent effect associated with its efficacy in preventing GVHD, including reduced ...
Hsuan‐Hao Fan +3 more
wiley +1 more source
Tumor‐Bearing Status Accelerates Bleomycin‐Induced Pulmonary Inflammation via Endothelial Activation
Thoracic Cancer, Volume 17, Issue 7, April 2026.In subcutaneous tumor‐bearing mice, inflammatory cell infiltration into the lung was aggravated via endothelial activation. The tumor‐bearing status additively aggravated BLM‐induced lung inflammation. Proinflammatory changes in the lungs accelerated by tumor‐bearing status might be involved in the development of drug‐induced lung inflammation ...
Shoko Isoyama +11 more
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Cellular composition of the spleen from naive and T. cruzi- infected mice.
, 2013 Single spleen cell suspensions from naive mice (A) and from mice infected on day 24 with T. cruzi (B) were analysed by flow cytometry. Cells were stained for both CD4 and CD8, for CD19, for CD11b, or with propidium iodide (PI) and ...
Christiane Steeg (379481) +6 more
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