Results 51 to 60 of about 1,188,690 (195)

Effects of donor oocytes and culture conditions on development of cloned mice embryos

open access: yes, 2003
Mice have been successfully cloned from somatic and embryonic stem (ES) cells using the "Honolulu method." In the present study, different donor oocytes and different culture conditions were compared to evaluate the developmental potential of nuclear ...
PRIDDLE H.   +9 more
core   +2 more sources

NAD+ Metabolism Licenses Zygotic Genome Activation via PARP7‐Mediated ADP‐Ribosylation of UHRF1 in Mouse Early Embryos

open access: yesAdvanced Science, Volume 13, Issue 51, 14 September 2026.
This study uncovers a metabolic‐epigenetic axis licensing zygotic genome activation (ZGA) in mouse embryos. A developmental decline in NAD+ levels activates PARP7, which mono‐ADP‐ribosylates and stabilizes UHRF1. This modification promotes the establishment of permissive histone acetylation marks, thereby facilitating timely ZGA.
Guangyi Cao   +13 more
wiley   +1 more source

Tau, synaptophysin and spinophilin levels in the medial preoptic area in orchidectomized B6D2F1 hybrid male mice.

open access: yes, 2013
B6D2F1 hybrid males that continued to demonstrate male sexual behavior after long-term orchidectomy (“maters”) have significantly more tau, synaptophysin and spinophilin in the MPOA (A-C) and more synaptophysin and spinophilin in the medial amygdala (D-E)
Pranay Bharadwaj (127545)   +6 more
core   +1 more source

Humoral immune responses mediate the development of a restrictive phenotype of chronic lung allograft dysfunction

open access: yesJCI Insight, 2020
Understanding the distinct pathogenic mechanisms that culminate in allograft fibrosis and chronic graft failure is key in improving outcomes after solid organ transplantation.
Keizo Misumi   +13 more
doaj   +1 more source

Performance of C57BL/6J, DBA/2J, and B6D2F1 mice in a free-operant avoidance task [PDF]

open access: yesBulletin of the Psychonomic Society, 1980
Male mice (Mus musculus) 12–16 weeks of age from the C57BL/6J and DBA/2J inbred strains and B6D2F1 hybrids were trained at one of two shock levels (.5 or 2.0 mA) in a wheel-turn avoidance task during one 60-min session. Following two 10-min blocks during which no shock was given, a free-operant avoidance program was activated that required the animal ...
Ingram, D K, Sprott, R L
openaire   +1 more source

Gonadal Steroid-Independent Sexual Behavior in Female and Male B6D2F1 Gonadectomized Mice

open access: yes, 2020
Mechanisms underlying the regulation of either male or female reproductive behavior in the absence of gonadal hormones are not well understood. Further investigation will lead to better understanding of the prevalent individual differences observed in ...
Templin, Jay Scott
core   +1 more source

Microtubule Inner Protein CFAP77 Contributes to Sperm Motility and Male Fertility in Mice

open access: yesAndrology, Volume 14, Issue 5, Page 1240-1248, July 2026.
ABSTRACT Background Sperm motility is essential for male fertility, and its regulation is dependent on the structural integrity of the axoneme. The axoneme consists of a conserved “9+2” microtubule arrangement and is supported by microtubule inner proteins. However, the functional significance of many microtubule inner proteins remains unclear.
Haoting Wang   +4 more
wiley   +1 more source

Supplementary Table S3 from Preclinical Antitumor Activity of Cabazitaxel, a Semisynthetic Taxane Active in Taxane-Resistant Tumors

open access: yes, 2013
Supplementary Table S3 - PDF file 53K, Schedule of cabazitaxel administration in non-tumor-bearing B6D2F1 female ...
Cecile Combeau (14990934)   +9 more
core   +1 more source

An Outflow Tract Myocardium‐Specific Enhancer at the Sema3c Locus During Heart Development

open access: yesGenes to Cells, Volume 31, Issue 4, July 2026.
Focusing on an OFT‐specific differentially accessible region, in the present study, we defined a distal OFT myocardial enhancer whose activity depends on GATA binding sites. This enhancer provides insight into the mechanisms underlying spatially restricted Sema3c expression involved in OFT development.
Yunce Wang   +5 more
wiley   +1 more source

Fullerol treatment does not interfere with GVL in mice with experimental GVHD.

open access: yes, 2015
GVHD was induced by the transfer of splenocytes from allogeneic (C57BL/6J) donors to B6D2F1 mice. GFP+P815 cells were injected i.v. into the B6D2F1 recipients on day 0 of transplantation.
Maurício V. B. Pinheiro (721078)   +11 more
core   +1 more source

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