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Stimulation of B7-H1 in Hepatocarcinoma Cells by Hepatitis B virus X Antigen

Immunological Investigations, 2010
The cross-talk between the hepatitis B virus X protein (HBx) and B7-H1 in hepatocarcinoma (HCC) is unclear. This study analyzed the potential relationships between HBx and B7-H1 in hepatocarcinogenesis. One of human HCC cell lines, HepG2 cells, was transfected to stably express HBx protein (HBx(+)-HepG2).
Shengxi, Wu   +7 more
openaire   +2 more sources

Potent Systemic Antitumor Immunity Induced by Vaccination with Chemotactic-Prostate Tumor Associated Antigen Gene-Modified Tumor Cell and Blockade of B7-H1

Journal of Clinical Immunology, 2006
We previously reported that several DNA fragments from human prostate-specific membrane antigen (hPSM), mouse prostatic acid phosphatase (mPAP), and human prostate-specific antigen (hPSA) genes were selected and fused to create a novel hPSM-mPAP-hPSA fusion gene (named 3P gene), and human secondary lymphoid tissue chemokine (SLC), 3P, and human IgG Fc ...
Ning, Li   +9 more
openaire   +2 more sources

Blockade of PD-1/B7-H1 interaction restores antigen-specific CD8+ T cell responses in HCV core transgenic mice (47.8)

The Journal of Immunology, 2007
Abstract Impaired CD8+ T cells have been implicated to play a role in the establishment of HCV persistent infection. HCV has evolved multiple strategies to avoid T cell responses. HCV core protein has been shown to contain immunomodulatory functions.
John R Lukens, Young S Hahn
openaire   +1 more source

TLR 7/8 agonist resiquimod alleviates murine allergic asthma through IL-27 production and up regulation of B7-H1 on antigen presenting cells

5.3 Allergy and Immunology, 2015
Background: Counter balancing Th2-cytokine production through enhanced skewing of CD4+ T helper cells into Th1 cells is currently one of the central immunomodulatory approaches for treatment of allergic diseases. Methods: We systemically sensitized mice followed by intranasal challenge with the model allergen.
Kathleen Daluge   +3 more
openaire   +1 more source

Abstract 2935: Modulation of immune checkpoint B7-H1/B7-DC/PD-1 interaction in combination with live attenuated Listeria monocytogenes expressing a tumor associated antigen effectively treats hepatic colorectal cancer metastases

Cancer Research, 2010
Abstract Introduction: The successful eradication of tumor deposits by immunotherapy requires the generation of an appropriate primary and memory immune effector immune response as well as the establishment of a tumor micro-environment within that organ to target, traffic and amplify the appropriate immune response. B7-H1 is expressed on
Kiyoshi Yoshimura   +7 more
openaire   +1 more source

Faculty Opinions recommendation of B7-H1-expressing antigen-presenting cells mediate polarization of protumorigenic Th22 subsets.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature, 2014
Philippe Saas, Sylvain Perruche
openaire   +1 more source

Critical care management of chimeric antigen receptor T‐cell therapy recipients

Ca-A Cancer Journal for Clinicians, 2022
Alexander Shimabukuro-Vornhagen   +2 more
exaly  

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