Results 41 to 50 of about 4,559,918 (199)

B cells and atherosclerosis [PDF]

American Journal of Physiology-Heart and Circulatory Physiology, 2017
B cells have emerged as important immune cells in cardiovascular disease. Initial studies have suggested that B cells protect against atherosclerosis development. However, subsequent studies demonstrating aggravation of atherosclerosis by B-2 cells have shed light on the subset-dependent effects of B cells.
Coleen A. McNamara, Prasad Srikakulapu
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B cells and autoimmunity [PDF]

Current Opinion in Immunology, 2011
There is a growing appreciation for the role for B cells in autoimmune disorders in which inflammation is driven by T cells, in addition to the well-established role for B cells in autoimmune disorders characterized by pathogenic auto-antibodies. Current information on tolerance checkpoints in B cells, B cell depletion, BAFF blockade, regulatory B ...
Annaiah Cariappa, Shiv Pillai, Hamid Mattoo   +2 more
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Glycosylated nanoparticle-based PfCSP vaccine confers long-lasting antibody responses and sterile protection in mouse malaria model

npj Vaccines, 2023
The development of an effective and durable vaccine remains a central goal in the fight against malaria. Circumsporozoite protein (CSP) is the major surface protein of sporozoites and the target of the only licensed Plasmodium falciparum (Pf) malaria ...
Julia Ludwig, Stephen W. Scally, Giulia Costa, Sandro Hoffmann, Rajagopal Murugan, Jana Lossin, Katherine Prieto, Anna Obraztsova, Nina Lobeto, Blandine Franke-Fayard, Chris J. Janse, Celia Lebas, Nicolas Collin, Spela Binter, Paul Kellam, Elena A. Levashina, Hedda Wardemann, Jean-Philippe Julien   +17 more
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B Cell Immunosenescence

Annual Review of Cell and Developmental Biology, 2020
Innate and adaptive immune responses decline with age, leading to greater susceptibility to infectious diseases and reduced responses to vaccines. Diseases are more severe in old than in young individuals and have a greater impact on health outcomes such as morbidity, disability, and mortality.
Bonnie B. Blomberg, Daniela Frasca, Denisse Garcia, Alain Diaz, Maria Romero   +4 more
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Advancements in understanding the regulatory mechanism of B-cell immune activation associated with adenotonsillar hypertrophy

生物医学转化
B cells play a crucial role in recognizing external antigens through their surface B cell receptor (BCR), essential for generating protective antibodies and immune memory.
Chen Wenjing, Gao Ruiyu, Huang Jingwen, Ye Jingying, Liu Wanli   +4 more
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Nutrient sensing and cAMP signaling in yeast: G-protein coupled receptor versus transceptor activation of PKA

Microbial Cell, 2020
A major signal transduction pathway regulating cell growth and many associated physiological properties as a function of nutrient availability in the yeast Saccharomyces cerevisiae is the protein kinase A (PKA) pathway.
Griet Van Zeebroeck, Liesbeth Demuyser, Zhiqiang Zhang, Ines Cottignie, Johan M. Thevelein   +4 more
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Effects of Exogenous Proteins Injection into the Bursa of Fabricius on Humoral Immunity in Neonatal Chickens

The Journal of Poultry Science, 2012
Early researches have shown that the bursa of Fabricius is a critical organ for development of B lymphocytes in birds. Exogenous proteins from the gut lumen or the environment are taken up by the follicle-associated epithelium and enter into the bursal ...
Fang Yuan, Guojin Wu, Junshuang Gao, Xiaoyan Tang, Zandong Li   +4 more
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The Impact of Obesity on the Outcomes of Adult Patients with Acute Lymphoblastic Leukemia – A Single Center Retrospective Study

Blood and Lymphatic Cancer: Targets and Therapy, 2021
Qiuju Liu,1 Brittny Major,2 Jennifer Le-Rademacher,2 Aref A Al-Kali,3 Hassan Alkhateeb,3 Kebede Begna,3 Michelle A Elliott,3 Naseema Gangat,3 William J Hogan,3 C Christopher Hook,3 Scott H Kaufmann,3 Animesh Pardanani,3 Mrinal S Patnaik,3 Ayalew Tefferi ...
Liu Q, Major B, Le-Rademacher J, Al-Kali AA, Alkhateeb H, Begna K, Elliott MA, Gangat N, Hogan WJ, Hook CC, Kaufmann SH, Pardanani A, Patnaik MS, Tefferi A, Wolanskyj-Spinner AP, Wei W, Litzow MR   +16 more
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CD19 and POU2AF1 are Potential Immune-Related Biomarkers Involved in the Emphysema of COPD: On Multiple Microarray Analysis

Journal of Inflammation Research, 2022
Da-Wei Zhang,1,2,* Jing-Jing Ye,1,2,* Ying Sun,1,2 Shuang Ji,1,2 Jia-Ying Kang,1,2 Yuan-Yuan Wei,1,2 Guang-He Fei1,2 1Department of Respiratory and Critical Care Medicine, First Affiliated Hospital of Anhui Medical University, Hefei, 230022 ...
Zhang DW, Ye JJ, Sun Y, Ji S, Kang JY, Wei YY, Fei GH   +6 more
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The Pathogenesis of Nephrotic Syndrome: A Perspective from B Cells

Kidney Diseases
Background: Nephrotic syndrome is a special type of chronic kidney disease, the specific pathogenesis of which remains unclear. An increasing number of studies have suggested that B cells play an important role in the pathogenesis of nephrotic syndrome ...
Shifan Zhu, Jiayu Zhang, Langping Gao, Qing Ye, Jianhua Mao   +4 more
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