Results 41 to 50 of about 31,066,857 (388)
Case Reports in Oncology, 2021 Primary CNS extranodal marginal zone B-cell lymphoma (MZBL) is a rare low-grade non-Hodgkin lymphoma characterized predominantly by small B cells, plasma cells, monocytoid cells, and scattered large immunoblasts.
Rojine Ariani, Leslie Ballas
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T cell–B cell collaboration [PDF]
Nature Reviews Immunology, 2017 Jonathan Sprent describes a 1968 study by Graham Mitchell and Jacques Miller that showed the requirement for T cell–B cell collaboration for antibody production.
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Immunological Medicine, 2021 Rheumatoid arthritis (RA) is a systemic autoimmune mediated inflammatory disease characterized by progressive joint damage and extra-articular organ manifestations.
Shizuyo Tsujimura, Yoshiya Tanaka
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New England Journal of Medicine, 2002 BACKGROUND The survival of patients with diffuse large-B-cell lymphoma after chemotherapy is influenced by molecular features of the tumors. We used the gene-expression profiles of these lymphomas to develop a molecular predictor of survival.
A. Rosenwald +39 more
semanticscholar +1 more source
SDF-1 and PDGF enhance [alpha]v[beta]5-mediated ERK activation and adhesion-independent growth of human pre-B cell lines [PDF]
, 2009 CD23 acts through the [alpha]v[beta]5 integrin to promote growth of human pre-B cell lines in an adhesion-independent manner. [alpha]v[beta]5 is expressed on normal B-cell precursors in the bone marrow.
Acharya, M. +3 more
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T-cells and B-cells in osteoporosis [PDF]
Current Opinion in Endocrinology, Diabetes & Obesity, 2014 Bone disease is a leading cause of fractures and continues to be a source of significant morbidity and mortality worldwide. As the underlying mechanisms of osteoporosis are elucidated, immune dysfunction continues to emerge as a key precipitating factor in multiple bone disease contexts. This review examines recent findings in the osteoimmunology field
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Initial B Cell Activation Induces Metabolic Reprogramming and Mitochondrial Remodeling. [PDF]
, 2018 B lymphocytes provide adaptive immunity by generating antigen-specific antibodies and supporting the activation of T cells. Little is known about how global metabolism supports naive B cell activation to enable an effective immune response.
Ahsan, Fasih M +4 more
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Immunology Today, 1982 The influenza virus behaves unpredictably and can cause devastating pandemics. Nearly 50 years after its first isolation it is probably the most infectious agent known that we cannot yet control. Why? The answer lies in the virus's unique capacity to alter antigenically and in the inability of the host's immune system to respond satisfactorily to the ...
Mcmichael, A +3 more
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Sequential induction of NF-κB/Rel family proteins during B-cell terminal differentiation [PDF]
, 1994 The NF-kappa B/Rel family of at least five transcription factor polypeptides is thought to function both as a developmental regulator in B cells and as a rapid response system in all cells. To examine this notion in more detail, we determined the protein
Baltimore, David +3 more
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CD19 CAR-T cells of defined CD4+:CD8+ composition in adult B cell ALL patients.
Journal of Clinical Investigation, 2016 BACKGROUND T cells that have been modified to express a CD19-specific chimeric antigen receptor (CAR) have antitumor activity in B cell malignancies; however, identification of the factors that determine toxicity and efficacy of these T cells has been ...
C. Turtle +22 more
semanticscholar +1 more source