Results 41 to 50 of about 31,156,887 (403)

B-cell or T-cell immunity?

open access: yesImmunology Today, 1982
The influenza virus behaves unpredictably and can cause devastating pandemics. Nearly 50 years after its first isolation it is probably the most infectious agent known that we cannot yet control. Why? The answer lies in the virus's unique capacity to alter antigenically and in the inability of the host's immune system to respond satisfactorily to the ...
Mcmichael, A   +3 more
openaire   +4 more sources

Inhibition of oncogenic transcription factor REL by the natural product derivative calafianin monomer 101 induces proliferation arrest and apoptosis in human B-lymphoma cell lines [PDF]

open access: yes, 2015
Increased activity of transcription factor NF-κB has been implicated in many B-cell lymphomas. We investigated effects of synthetic compound calafianin monomer (CM101) on biochemical and biological properties of NF-κB.
Chennamadhavuni, Spandan   +4 more
core   +2 more sources

Morphologic observations of human T and B lymphocytes by scanning electron microscopy [PDF]

open access: yes, 1974
T cell concerned with cell mediated immunity and B cell concerned with humoral antibody are classified by scanning electron microscopy of the surface structure of lymphocytes using E binding lymphocytes and EAC (sensitized sheep erythrocytes treated with
Yamamoto, Isamu
core   +1 more source

Association of CD24, CD27, and co-stimulatory molecules CD80 immunological marker expression on B-cells of human peripheral blood with development of celiac disease

open access: yesIraqi Journal of Hematology
BACKGROUND: B-cells express a variety of clusters of differentiation markers during development. These markers determine the basic function of the immune phenotype specific to B-cells.
Rahab Abd-Ali Al-Madany   +1 more
doaj   +1 more source

Challenges and Opportunities for Consistent Classification of Human B Cell and Plasma Cell Populations

open access: yesFrontiers in Immunology, 2019
The increasingly recognized role of different types of B cells and plasma cells in protective and pathogenic immune responses combined with technological advances have generated a plethora of information regarding the heterogeneity of this human immune ...
I. Sanz   +7 more
semanticscholar   +1 more source

Primary mediastinal lymphoma: diagnosis and treatment options. [PDF]

open access: yes, 2014
Primary mediastinal large B-cell lymphoma (PMBCL) is a unique B-cell lymphoma variant that arises from a putative thymic medulla B cell. It constitutes 2-4% of non-Hodgkin lymphomas and occurs most frequently in young females. PMBCL is characterized by a
DI ROCCO, Alice   +4 more
core   +1 more source

Integrative Analysis by Mendelian Randomization and Large-Scale Single-Cell Transcriptomics Reveals Causal Links between B Cell Subtypes and Diabetic Kidney Disease

open access: yesKidney Diseases
Introduction: The increasing incidence of diabetic kidney disease (DKD) and the challenges in its management highlight the necessity for a deeper understanding of its pathogenesis.
Yuan Ma   +7 more
doaj   +1 more source

B cell memory: building two walls of protection against pathogens

open access: yesNature reviews. Immunology, 2019
Surviving a single infection often results in lifelong immunity to the infecting pathogen. Such protection is mediated, in large part, by two main B cell memory ‘walls’ — namely, long-lived plasma cells and memory B cells.
M. Akkaya, Kihyuck Kwak, S. Pierce
semanticscholar   +1 more source

B cells in multiple sclerosis

open access: yesAutoimmunity, 2017
B lymphocytes have essential roles in the autoimmune pathogenesis of multiple sclerosis (MS). They regulate the autoimmune response and participate in the development of the CNS lesions.
Hartmut Wekerle
doaj   +1 more source

B-cell Tolerance

open access: yesTransplantation, 2006
Autoreactive B cells are actively tolerized to more abundant self-antigens by a series of checkpoints involving receptor editing, deletion, anergy and competition for growth factors. In contrast, B cells reactive against rare, sequestered or tissue specific self-antigens remain functionally naïve.
Ferry, H   +6 more
openaire   +3 more sources

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