Results 241 to 250 of about 216,975 (333)

Intracellular and Extracellular Efficacy of Homoisoflavone Derivatives Against Mycobacterium Tuberculosis: Progress Toward Novel Antitubercular Agents

open access: yesChemMedChem, EarlyView.
A series of 42 homoisoflavones were synthesized and evaluated against Mycobacterium tuberculosis (Mtb). Three derivatives showed potent inhibition of Mtb strains. Evaluation in infected macrophages revealed promising intracellular activity, where one derivative featuring a nitrofuranyl and piperidine group emerges as the most promising.
Sanderson D. Calixto   +12 more
wiley   +1 more source

THE TRANSFORMATION OF TYPHOID BACILLI INTO L FORMS UNDER VARIOUS CONDITIONS [PDF]

open access: bronze, 1950
L. Dienes   +2 more
openalex   +1 more source

Sustainable Synthesis, Characterization, Cellular Effects of Gold Nanoparticles and Their Applications as Therapeutics in Cancer Therapy

open access: yesChemPlusChem, EarlyView.
Gold nanoparticles (AuNPs) are widely used in biomedicine, electronics, catalysis, and environmental science. Conventional synthesis relies on harsh chemicals, driving interest in eco‐friendly methods using plants, bacteria, fungi, and algae. Biomolecules like polyphenols, proteins, and fatty acids aid nanoparticle synthesis under mild conditions. This
Youfeng Yue   +3 more
wiley   +1 more source

Studies of the Common Aerobic Spore-forming Bacilli [PDF]

open access: bronze, 1942
Kenneth L. Burdon   +2 more
openalex   +1 more source

Population Pharmacokinetic/Toxicodynamic Model for Polymyxin B in Critically Ill Patients to Identify the Risk of Nephrotoxicity

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Polymyxins are used against highly resistant Gram‐negative pathogens, and nephrotoxicity (acute kidney injury, AKI) is the major dose‐limiting adverse effect. We aimed to develop a well‐informed population pharmacokinetic/toxicodynamic (PK/TD) model using the largest polymyxin B‐treated critically ill patient population studied to inform polymyxin B ...
Patrick O. Hanafin   +19 more
wiley   +1 more source

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