Results 91 to 100 of about 1,274,653 (285)

Concerning the matching of magnetic susceptibility differences for the compensation of background gradients in anisotropic diffusion fibre phantoms. [PDF]

PLoS ONE, 2017
Artificial, anisotropic fibre phantoms are nowadays increasingly used in the field of diffusion-weighted MRI. Such phantoms represent useful tools for, among others, the calibration of pulse sequences and validation of diffusion models since they can ...
Ezequiel Farrher, Johannes Lindemeyer, Farida Grinberg, Ana-Maria Oros-Peusquens, N Jon Shah   +4 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Background colour matching in a wild population of Alytes obstetricans

Amphibia-Reptilia, 2016
The capacity for physiological colour change has long been described in anuran amphibians. Camouflage against predators seems to be the most relevant function of dynamic changes in skin colour of frogs, but key aspects such as the rate at which these changes occur, or the specific colour components involved are not completely clear.
Polo Cavia, Nuria, Oliveira, José Miguel, Redondo Villa, Alberto José, Márquez, Rafael   +3 more
openaire   +2 more sources

Hidden Conformal Symmetry of the Reissner-Nordstr{\o}m Black Holes

, 2010
Motivated by recent progresses in the holographic descriptions of the Kerr and Reissner-Nordstr{\o}m (RN) black holes, we explore the hidden conformal symmetry of nonextremal uplifted 5D RN black hole by studying the near horizon wave equation of a ...
A Castro, A Castro, A Castro, A Castro, AJ Amsel, AJ Amsel, AM Ghezelbash, C Krishnan, C Krishnan, C-M Chen, C-M Chen, C-M Chen, Chiang-Mei Chen, D Astefanesei, DDK Chow, E Witten, F Loran, G Compere, H Isono, H Lü, H Lü, I Bredberg, J-J Peng, J-J Peng, JD Brown, Jia-Rui Sun, JM Maldacena, K Hotta, K Hotta, L Susskind, M Alishahiha, M Cvetič, M Guica, MR Garousi, OJC Dias, SS Gubser, T Azeyanagi, T Azeyanagi, T Azeyanagi, T Hartman, T Hartman, T Hartman, V Balasubramanian, X-N Wu, Y Matsuo, Y Nakayama   +45 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Host defense triggers rapid adaptive radiation in experimentally evolving parasites

Evolution Letters, 2019
Adaptive radiation occurs when the members of a single lineage evolve different adaptive forms in response to selection imposed by competitors or predators.
Sarah E. Bush, Scott M. Villa, Juan C. Altuna, Kevin P. Johnson, Michael D. Shapiro, Dale H. Clayton   +5 more
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Factors Driving Background Choice in Scorpionfish

Ecology and Evolution
For a successful hunt, marine ambush predators such as scorpionfish need to be well camouflaged to deceive their prey. When the natural environment is heterogeneous, one strategy to maintain camouflage is choosing backgrounds to achieve better crypsis ...
Leonie John, Matteo Santon, Nico K. Michiels   +2 more
doaj   +1 more source

One-loop anomalous couplings and matching conditions in the nonlinear realization of the SU(2) Higgs Model

, 2004
We study the renormalization of the nonlinear realization of the SU(2) Higgs model in the modified minimal subtraction renormalization scheme. We propose that the effective field method with truncated operator series is trustworthy even when the Higgs ...
Appelquist, Appelquist, Appelquist, Arzt, Avramidi, Avramidi, Bilenky, Callen, Coleman, Denner, DeWitt, DeWitt, Dittmaier, Dittmaier, Espriu, Gasser, Gasser, Georgi, Georgi, Grosse-Knetter, Grosse-Knetter, Haag, Hagiwara, Herrero, Herrero, Higgs, Kaoru Hagiwara, Lee, Longhitano, Longhitano, Pich, Polchinski, Qi-Shu Yan, Scherer, Sukanta Dutta, Weinberg, Wilson, Woodhouse, Yan   +38 more
core   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source