Results 91 to 100 of about 362,507 (292)

Matching Multiple Backgrounds: Egg Camouflage Across Different Habitats in a Shorebird

Ecology and Evolution
For species found in multiple habitats, the problem of camouflage against visually different backgrounds can be challenging. This is particularly so for bird eggs in open nests, as the scope for movement or alternative defensive strategies is limited. We
Alexandra Grandón‐Ojeda, Tamás Székely, Robert N. Kelsh, Alejandro Pérez‐Hurtado, Innes C. Cuthill   +4 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

"Statistical Matching Using Propensity Scores: Theory and Application to the Levy Institute Measure of Economic Wellbeing" [PDF]

This paper summarizes the background, type, logic, and working procedure of the statistical matching used in the Levy Institute Measure of Economic Wellbeing (LIMEW) project to combine the various data sets used to produce the synthetic data set with ...
Hyunsub Kum, Thomas Masterson
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Background characteristics of the TRD and non-TRD populations before and after matching.

, 2022
Background characteristics of the TRD and non-TRD populations before and after matching.
Kristoffer Jarlov Jensen (6917828), Espen Jimenez-Solem (291132), Jesper Riise (311666), Nikolaj Bødker (13870996), Mikkel Zöllner Ankarfeldt (11740700), Frederikke Hørdam Gronemann (13870993), Merete Osler (231830), Sarah Alulis (8518824), Janne Petersen (94661)   +8 more
core   +1 more source

Crypsis by background matching and disruptive coloration as drivers of substrate occupation in sympatric Amazonian bark praying mantises. [PDF]

Sci Rep, 2023
de Alcantara Viana JV, Campos Duarte R, Vieira C, Augusto Poleto Antiqueira P, Bach A, de Mello G, Silva L, Rabelo Oliveira Leal C, Quevedo Romero G.   +8 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Evaluation of Stereo Matching Costs on Images with Radiometric Differences

, 2009
Stereo correspondence methods rely on matching costs forcomputing the similarity of image locations. We evaluate the insensitivity of different costs for passive binocular stereo methods with respect to radiometric variations of the input images.
Hirschmüller, Heiko, Scharstein, Daniel
core