Results 61 to 70 of about 21,556 (197)

Polypharmacy among adolescents and adults with cerebral palsy in a clinical setting

PM&R, EarlyView.
Abstract Background Adolescents and adults with cerebral palsy often experience multimorbidity related to their condition, which primarily affects movement and posture but is also associated with pain, epilepsy, mood disorders, and other conditions. As such, these patients are often prescribed a range of medications to manage symptoms, thereby putting ...
Caitlin Cassidy, Joshua C. Wiener, Karen Pratt, Laura Brunton   +3 more
wiley   +1 more source

Severe Case of Oral Baclofen Withdrawal Resulting in Mechanical Ventilation

Journal of Investigative Medicine High Impact Case Reports, 2022
Abrupt baclofen withdrawal may be life-threatening with varied neuropsychiatric manifestations. We present a case of baclofen withdrawal necessitating intubation.
Resha Khanal, Sharad Oli, Janet Chan Gomez, Sahar Tahir, Binita Bhandari, Saketram Komanduri   +5 more
doaj   +1 more source

NMES-Facilitated Mandibular Rehabilitation for Spasticity-Related Trismus in ALS. [PDF]

Muscle Nerve
Muscle &Nerve, Volume 74, Issue 3, Page 747-750, September 2026.
Salmon K, Ilieva H, Kelly D.
europepmc   +2 more sources

Efficacy and safety of pharmacological interventions for the treatment of cocaine use disorder: A systematic review and network meta‐analysis

Addiction, EarlyView.
Abstract Background and aims Cocaine use disorder (CUD) is an increasingly widespread concern worldwide. Various pharmacological treatments have been investigated for CUD, but their efficacy remains unclear, and none have been licensed for treatment.
Craig Paterson, Thomas Parkhouse, Chloe Burke, Monika Halicka, Jennifer C. Palmer, Hend Gabr, Rebecca Wilson, Katie E. Webster, Francesca Spiga, Sarah Dawson, Deborah M. Caldwell, Jennifer Scott, Julian P. T. Higgins, Jelena Savović   +13 more
wiley   +1 more source

Central sleep apnea caused by low dosage of baclofen: a case report

Journal of Medical Case Reports
Background Baclofen can relax muscle spasticity by inhibiting the transmission of both mono- and polysynaptic reflexes at the spinal cord. It has been increasingly used off-label for the management of spinal cord lesions or neurologic disorders. However,
Xiaoqiong Luo, Qidi Ding, Yanan Liu, Fang Han, Chenyu Li, Xiaosong Dong   +5 more
doaj   +1 more source

Protective effect of baclofen on ovarian cystogenesis and morphine-induced lipid profile change in female rats

Indian Journal of Endocrinology and Metabolism
Introduction: Morphine induces ovarian cysts that cause obesity and disrupt sex hormone secretion. Baclofen, a gamma-aminobutyric acid receptor agonist, can help regulate sex hormones and reduce harmful blood lipids by protecting against morphine-induced
Zahra Jamshidi, Manizheh Karami, Mohsen Khalili, Mehrdad Roghani   +3 more
doaj   +1 more source

Using Baclofen to Explore GABA-B Receptor Function in Alcohol Dependence: Insights From Pharmacokinetic and Pharmacodynamic Measures

Frontiers in Psychiatry, 2018
Background: The role of GABA-B neurotransmission in addiction has recently received increased attention, with clinical trials indicating that baclofen, a GABA-B receptor agonist, may reduce alcohol consumption, craving and promote abstinence.
Claire F. Durant, Louise M. Paterson, Sam Turton, Susan J. Wilson, James F. M. Myers, Suresh Muthukumaraswamy, Ashwin Venkataraman, Inge Mick, Susan Paterson, Tessa Jones, Limon K. Nahar, Rosa E. Cordero, David J. Nutt, Anne Lingford-Hughes   +13 more
doaj   +1 more source

Baclofen overdose: A curious case of medical sales representative

Clinical Case Reports, 2022
In this case report, a medical sales representative consumed 250 mg of Baclofen out of curiosity. Baclofen has life‐threatening complications like seizures, respiratory depression, and coma.
Swotantra Gautam, Aakash Neupane, Mandita Chamlagain, Sandip Pokhrel, Durga Neupane, Rochana Acharya, Sagar Panthi   +6 more
doaj   +1 more source

Risk Factors for Complications Following Paediatric Neuromuscular and Syndromic Scoliosis Correction Surgery: A Systematic Review

ANZ Journal of Surgery, EarlyView.
ABSTRACT Background Paediatric neuromuscular and syndromic scoliosis patients have multiple medical comorbidities that increase the risk of postoperative complications. There is a lack of consistent literature assessing the specific risk factors for complications following scoliosis correction surgery in this high‐risk cohort.
Mai Pham, Mia A. Percival, Moya Vandeleur, Giuliana Antolovich, Kris Lundine   +4 more
wiley   +1 more source

FLUORODENSITOMETRIC DETERMINATION OF BACLOFEN

, 1990
A fluorodensitometric method was developed for the determination of baclofen. The method is based on the reaction of baclofen with 4-chloro-7-nitrobenzofurazan and measurement of the fluoresence intensity at 540 nm after chromatographic separation on a ...

core   +1 more source