Results 41 to 50 of about 15,483 (191)
Objective This study aimed to explore the effects of activating GABAB1 receptor by baclofen on proliferation, migration, invasion and epithelial-mesenchymal transition (EMT) of ovarian cancer cells.
Jun Gao +7 more
doaj +1 more source
Solubility of baclofen in 1-hexyl-4-methylpyridinium bromide + water binary mixtures [PDF]
In this paper, solubility of baclofen was studied by gravimetric method. The solubility of baclofen was measured in (water + 1-hexyl-4-methylpyridinium bromide) binary mixtures from 293.1 K to 313.1 K under atmosphere pressure.
Abbas Mehrdad +2 more
doaj +1 more source
The aim of the study was to evaluate the overtime histological changes in the lungs after intoxication with baclofen alone or in combination with ethanol.Materials and methods.
O. L. Romanova +5 more
doaj +1 more source
SPG4 Hereditary Spastic Paraplegia: From Etiology to Therapy
Abstract Hereditary spastic paraplegias (HSPs) comprise a heterogeneous group of heritable neurodegenerative disorders resulting from mutations in a wide variety of genes. HSP locomotor symptoms include lower limb weakness and spasticity that arise from progressive degeneration of corticospinal axons projecting from the motor cortex to the distal ...
Emanuela Piermarini, Peter W. Baas
wiley +1 more source
Despite documented cases of baclofen toxicity in individuals with kidney disease, the drug is widely prescribed for various medical conditions, primarily spasticity, hiccups, and multiple sclerosis.
Nejah F. Ellouze +2 more
doaj +1 more source
Abstract Background and Objective Previous work from this dataset found 45% prescribing frequency of any medications (35.1%, 33.5%, and 56.8% at institutions 1, 2, and 3 respectively), without significant difference between in‐person and telemedicine.
Matthew Chen +7 more
wiley +1 more source
Polypharmacy among adolescents and adults with cerebral palsy in a clinical setting
Abstract Background Adolescents and adults with cerebral palsy often experience multimorbidity related to their condition, which primarily affects movement and posture but is also associated with pain, epilepsy, mood disorders, and other conditions. As such, these patients are often prescribed a range of medications to manage symptoms, thereby putting ...
Caitlin Cassidy +3 more
wiley +1 more source
Correlation between the single, high dose of ingested baclofen and clinical symptoms
Introduction and Objectives Baclofen is a drug used mainly to treat muscle spasticity. Its overdose can lead to life-threatening clinical symptoms, including acute respiratory failure requiring mechanical ventilation.
Jacek Sein Anand +5 more
doaj +1 more source
Severe Case of Oral Baclofen Withdrawal Resulting in Mechanical Ventilation
Abrupt baclofen withdrawal may be life-threatening with varied neuropsychiatric manifestations. We present a case of baclofen withdrawal necessitating intubation.
Resha Khanal +5 more
doaj +1 more source
Introduction: Morphine induces ovarian cysts that cause obesity and disrupt sex hormone secretion. Baclofen, a gamma-aminobutyric acid receptor agonist, can help regulate sex hormones and reduce harmful blood lipids by protecting against morphine-induced
Zahra Jamshidi +3 more
doaj +1 more source

