Results 41 to 50 of about 15,483 (191)

Effects of activating GABAB1 receptor on proliferation, migration, invasion and epithelial-mesenchymal transition of ovarian cancer cells

open access: yesJournal of Ovarian Research, 2020
Objective This study aimed to explore the effects of activating GABAB1 receptor by baclofen on proliferation, migration, invasion and epithelial-mesenchymal transition (EMT) of ovarian cancer cells.
Jun Gao   +7 more
doaj   +1 more source

Solubility of baclofen in 1-hexyl-4-methylpyridinium bromide + water binary mixtures [PDF]

open access: yesشیمی کاربردی روز, 2017
In this paper, solubility of baclofen was studied by gravimetric method. The solubility of baclofen was measured in (water + 1-hexyl-4-methylpyridinium bromide) binary mixtures from 293.1 K to 313.1 K under atmosphere pressure.
Abbas Mehrdad   +2 more
doaj   +1 more source

Overtime Histological Changes in the Lungs after Intoxication with Baclofen Alone or in Combination with Ethanol (Experimental Study)

open access: yesОбщая реаниматология, 2023
The aim of the study was to evaluate the overtime histological changes in the lungs after intoxication with baclofen alone or in combination with ethanol.Materials and methods.
O. L. Romanova   +5 more
doaj   +1 more source

SPG4 Hereditary Spastic Paraplegia: From Etiology to Therapy

open access: yesMovement Disorders, EarlyView.
Abstract Hereditary spastic paraplegias (HSPs) comprise a heterogeneous group of heritable neurodegenerative disorders resulting from mutations in a wide variety of genes. HSP locomotor symptoms include lower limb weakness and spasticity that arise from progressive degeneration of corticospinal axons projecting from the motor cortex to the distal ...
Emanuela Piermarini, Peter W. Baas
wiley   +1 more source

Baclofen-induced neurotoxicity in a dialysis patient managed with continuous venovenous hemodialysis: A case report and literature review

open access: yesTurkish Journal of Emergency Medicine
Despite documented cases of baclofen toxicity in individuals with kidney disease, the drug is widely prescribed for various medical conditions, primarily spasticity, hiccups, and multiple sclerosis.
Nejah F. Ellouze   +2 more
doaj   +1 more source

Medication prescription patterns in cancer rehabilitation physiatry outpatients: A multicenter retrospective study

open access: yesPM&R, EarlyView.
Abstract Background and Objective Previous work from this dataset found 45% prescribing frequency of any medications (35.1%, 33.5%, and 56.8% at institutions 1, 2, and 3 respectively), without significant difference between in‐person and telemedicine.
Matthew Chen   +7 more
wiley   +1 more source

Polypharmacy among adolescents and adults with cerebral palsy in a clinical setting

open access: yesPM&R, EarlyView.
Abstract Background Adolescents and adults with cerebral palsy often experience multimorbidity related to their condition, which primarily affects movement and posture but is also associated with pain, epilepsy, mood disorders, and other conditions. As such, these patients are often prescribed a range of medications to manage symptoms, thereby putting ...
Caitlin Cassidy   +3 more
wiley   +1 more source

Correlation between the single, high dose of ingested baclofen and clinical symptoms

open access: yesAnnals of Agricultural and Environmental Medicine, 2017
Introduction and Objectives Baclofen is a drug used mainly to treat muscle spasticity. Its overdose can lead to life-threatening clinical symptoms, including acute respiratory failure requiring mechanical ventilation.
Jacek Sein Anand   +5 more
doaj   +1 more source

Severe Case of Oral Baclofen Withdrawal Resulting in Mechanical Ventilation

open access: yesJournal of Investigative Medicine High Impact Case Reports, 2022
Abrupt baclofen withdrawal may be life-threatening with varied neuropsychiatric manifestations. We present a case of baclofen withdrawal necessitating intubation.
Resha Khanal   +5 more
doaj   +1 more source

Protective effect of baclofen on ovarian cystogenesis and morphine-induced lipid profile change in female rats

open access: yesIndian Journal of Endocrinology and Metabolism
Introduction: Morphine induces ovarian cysts that cause obesity and disrupt sex hormone secretion. Baclofen, a gamma-aminobutyric acid receptor agonist, can help regulate sex hormones and reduce harmful blood lipids by protecting against morphine-induced
Zahra Jamshidi   +3 more
doaj   +1 more source

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