Results 31 to 40 of about 21,556 (197)

Baclofen Withdrawal–Induced Psychosis in the Setting of Renal Insufficiency

Journal of Investigative Medicine High Impact Case Reports, 2022
Baclofen is used to treat muscle spasticity, acting at GABA B receptors in the central nervous system. The abrupt cessation of baclofen causes baclofen withdrawal–induced psychosis. The risk is exacerbated if the patient has renal insufficiency or if the
Guilmette Amanda, Palushi Ambra, Shamsan Hundaol MD, Bhattacharyya Aniruddha MD, Michael Miriam MD   +4 more
doaj   +1 more source

Speaking fluently with baclofen? [PDF]

, 2017
Baclofen is a new and promising pharmacological compound for the treatment of alcohol dependence (AD). Although several randomised trials found a reduction of craving and higher abstinence rates with low and high doses of baclofen, others failed to show ...
van den Brink, W., Reinout Wiers, Beraha, Esther, Bodewits, Pieter, van den Brink, Wim, Pieter Bodewits, Wiers, R.; id_orcid, Esther Beraha, Bodewits, P., Wiers, Reinout, Wim van den Brink, Beraha, E.   +11 more
core   +1 more source

The Effect of Ginkgo on Baclofen Induced Amnesia using Passive Avoidance Learning and Memory in Rats [PDF]

Journal of Fasa University of Medical Sciences, 2015
Background & Objective: Ginkgo biloba is an herbal medicine that has a positive effect on improving memory. It prevents oxidative damage in mitochondria and cell death in a variety of Neuropathies.
Elaheh Nooshinfar, Mostafa Rezaei Tavirani, Akram Safaei, Yara Tambrchi   +3 more
doaj   +1 more source

A Case Report: Successful Management of Mixed Tardive Syndrome With Combination Pharmacotherapy in a 19‐Year‐Old Female With Schizophrenia [PDF]

Clin Case Rep
ABSTRACT A 19‐year‐old female with schizophrenia developed severe mixed tardive syndrome (choreoathetoid dyskinesia with prominent tardive dystonia) after antipsychotic treatment, which remained debilitating despite deutetrabenazine, benzodiazepines, baclofen, and amantadine.
Yang W, Li R, Cui Z, Wang H, Tan Q, Peng Z.   +5 more
europepmc   +2 more sources

How to Manage Self-Poisoning With Baclofen in Alcohol Use Disorder? Current Updates

Frontiers in Psychiatry, 2018
Specialists in addiction medicine continue to debate whether baclofen is still indicated to treat alcohol use disorders in view of conflicting results as to its efficacy.
Nicolas Franchitto, Nicolas Franchitto, Nicolas Franchitto, Benjamin Rolland, Benjamin Rolland, Fanny Pelissier, Nicolas Simon   +6 more
doaj   +1 more source

Is R(+)‐Baclofen the best option for the future of Baclofen in alcohol dependence pharmacotherapy? Insights from the preclinical side

, 2021
International audienceFor several decades, studies conducted to evaluate the efficacy of RS(+/-)-Baclofen in the treatment of alcohol dependence yielded contrasting results.
Vorspan, Florence, Bloch, Vanessa, Jérôme Jeanblanc, Vanessa Bloch, Florence Vorspan, Echeverry-Alzate, Victor, Jeanblanc, Jerome, Sauton, Pierre, Marion Soichot, Mickael Naassila, Laurence Labat, Pierre Sauton, Labat, Laurence, Soichot, Marion, Naassïla, Mickaël, Victor Echeverry‐Alzate   +15 more
core   +1 more source

Temporal Interference Stimulation of Centromedian‐Parafascicular Complex in Disorders of Consciousness: A Pilot Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Treatment of disorders of consciousness (DoC) remains a major clinical challenge, and noninvasive, targeted modulation of deep brain structures has emerged as a promising therapeutic strategy. We aimed to evaluate the feasibility/safety and preliminary effects of thalamic temporal interference stimulation (TIS) targeting centromedian‐
Gengyao Hu, Changgeng Song, Dianwei Wu, Xiaoqian Niu, Jianmin Hao, Lijuan Liu, Xiaogang Kang, Wen Jiang   +7 more
wiley   +1 more source

An autocrine role for pituitary GABA: Activation of GABA-B receptors and regulation of growth hormone levels [PDF]

, 2002
There is increasing evidence suggesting that the neurotransmitter gamma-aminobutyric acid (GABA) is a local factor involved in the regulation of endocrine organs.
Corsi, C., Pepeu, G., Gratzl, M., Gamel-Didelon, Katia, Jung, H., Mayerhofer, Artur   +5 more
core   +1 more source

An unusual case of baclofen abuse

Indian Journal of Psychological Medicine, 2016
Baclofen was initially used for the treatment of spastic conditions. Last decade has seen its emergence as a treatment of profound interest in alcohol dependence, opiates and cocaine abuse, and tobacco addiction.
Soumitra Das, Dhanya Sasidharan Palappalllil, Sumesh Thoppil Purushothaman, Varun Rajan   +3 more
doaj   +1 more source

Nickel‐Catalyzed Three‐Component Difluoroalkylation‐Amination for the Direct Access to Anti‐Inflammatory β‐Difluoroalkyl Amines

Advanced Science, EarlyView.
A nickel‐catalyzed three‐component reductive fluoroalkylation‐amination strategy of N‐vinylamides for the direct access to the α‐amidyl‐β‐difluoroalkyl amines was reported here. The synthetic method features with broad substrate scope, mild conditions, high functional group tolerance, and convenience to handle.
Chang Xu, Fangting Ma, Fan Ding, Luyan Wang, Yunxi Li, Yunzhi He, Xingang Zhang, Siyu He, Dandan Liu   +8 more
wiley   +1 more source