Results 61 to 70 of about 3,422,702 (354)

Physical Model of the Immune Response of Bacteria Against Bacteriophage Through the Adaptive CRISPR-Cas Immune System [PDF]

, 2013
Bacteria and archaea have evolved an adaptive, heritable immune system that recognizes and protects against viruses or plasmids. This system, known as the CRISPR-Cas system, allows the host to recognize and incorporate short foreign DNA or RNA sequences,
Barrick, Jeffrey E., Deem, Michael W., Han, Pu, Niestemski, Liang Ren   +3 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

First Culturing of Potential Bacterial Endophytes from the African Sahelian Crop Fonio Grown Under Abiotic Stress Conditions

Bacteria
In the African Sahel, fonio (Digitaria sp.) is a cereal crop that alleviates mid-season hunger before other main crops are harvested. As fonio is valued for its ability to grow under low nutrient and drought conditions, it was hypothesized that it may ...
Roshan Pudasaini, Eman M. Khalaf, Dylan J. L. Brettingham, Manish N. Raizada   +3 more
doaj   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

Avian and Human Turicibacter Isolates Possess Bile Salt Hydrolases with Activity Against Tauro-Conjugated Bile Acids

Bacteria
The genus Turicibacter is a common inhabitant of the small intestine of numerous animal species, including chickens. However, little is known about the phenotypic and genetic diversity of the genus.
Joel J. Maki, Lucas Showman, Torey Looft
doaj   +1 more source

The role of Bursaphelenchus xylophilus associated bacteria in pine wilt disease [PDF]

, 2012
Pine wilt disease (PWD) is a complex disease integrating three major factors: the causal agent, the pinewood nematode Bursaphelenchus xylophilus; the insect-vector Monochamus spp.; and the host pine tree, Pinus sp.
Barbosa, Pedro, Espada, Margarida, Glick, Bernard, Mota, Manuel, Nascimento, Francisco, Oliveira, Solange, Vicente, Cláudia   +6 more
core  

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Unveiling the Hidden Allies in the Fight Against Antimicrobial Resistance—Medicinal Plant Endophytes

Bacteria
Medicinal plants have long been a vital source of various natural products in the form of pure compounds or standardized extracts. The World Health Organization estimated that 80% of populations in Africa, Asia, and Latin America rely on traditional ...
Adeoye J. Kayode, Aboi Igwaran, Folasade Banji-Onisile, Nneka A. Akwu, John O. Unuofin, Ayodeji C. Osunla, Samson O. Egbewale, Hery Purnobasuki   +7 more
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Advancing Sustainable Management of Bacterial Spot of Peaches: Insights into Xanthomonas arboricola pv. pruni Pathogenicity and Control Strategies

Bacteria
Peach (Prunus persica) is a fruit crop of significant economic and cultural value, particularly in Japan, where it is cherished for its symbolism of summer and high quality.
Nanami Sakata, Yasuhiro Ishiga
doaj   +1 more source