Results 81 to 90 of about 4,344,868 (378)
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
BacteriaBiofilms, formed by microbial communities that increase resistance to antibiotics, are responsible for chronic infections, making their combat a therapeutic priority.
José Weverton Almeida-Bezerra +18 more
doaj +1 more source
大学トレーニングセンターにおけるトレーニング器具の衛生状況について [PDF]
, 2018 University training center users include those attempting to improve their health. There are reports of a tendency of annual increase in the number of elderly people visiting fitness clubs.
田中 淳, 畑島 紀昭
core +1 more source
Active skeleton for bacteria modeling
, 2016 The investigation of spatio-temporal dynamics of bacterial cells and their molecular components requires automated image analysis tools to track cell shape properties and molecular component locations inside the cells. In the study of bacteria aging, the
Dimiccoli, Mariella +2 more
core +3 more sources
FEBS Letters, EarlyView.Tuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Giulia Di Napoli +10 more
wiley +1 more source
Screening Lactic Acid Bacteria for Antimicrobial Compound Production [PDF]
, 2009 Lactic Acid Bacteria was known as potential probiotic used in food industries and dairy products and probable to produce antimicrobial compound that inhibit variety of microorganisms.
Khalisanni Khalid, Lee Hung Kiong
core +1 more source
Bacterial exchange in household washing machines [PDF]
, 2015 Household washing machines (WMs) launder soiled clothes and textiles, but do not sterilize them. We investigated the microbial exchange occurring in five household WMs. Samples from a new cotton T-shirt were laundered together with a normal laundry load.
Boon, Nico +4 more
core +2 more sources
Light-controlled bacteria-surface and bacteria-bacteria adhesions
, 2019 In bacterial biofilms, collective functions arise from the social interactions and spatial organization of bacteria. Controlling bacterial adhesion as key steps in biofilm formation with high spatial and temporal precision is essential for controlling the formation, organization and microstructure of biofilms.
openaire +4 more sources
Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation
FEBS Letters, EarlyView.The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen +2 more
wiley +1 more source
GABA Modulating Bacteria of the Human Gut Microbiota
Nature Microbiology, 2018 The gut microbiota affects many important host functions, including the immune response and the nervous system1. However, while substantial progress has been made in growing diverse microorganisms of the microbiota2, 23–65% of species residing in the ...
Philip Strandwitz +18 more
semanticscholar +1 more source