Results 21 to 30 of about 6,595 (270)

Gene Regulation of Biofilm-Associated Functional Amyloids

Pathogens, 2021
Biofilms are bacterial communities encased in a rigid yet dynamic extracellular matrix. The sociobiology of bacterial communities within a biofilm is astonishing, with environmental factors playing a crucial role in determining the switch from planktonic
Khushal Khambhati, Jaykumar Patel, Vijaylaxmi Saxena, Parvathy A, Neha Jain   +4 more
doaj   +1 more source

Purification of the Bacterial Amyloid “Curli” from Salmonella enterica Serovar Typhimurium and Detection of Curli from Infected Host Tissues

Bio-Protocol, 2022
Microbiologists are learning to appreciate the importance of “functional amyloids” that are produced by numerous bacterial species and have impacts beyond the microbial world. These structures are used by bacteria to link together, presumably to increase
Murugesan Sivaranjani, Elizabeth Hansen, Sumudu Perera, Pamela Flores, Cagla Tukel, Aaron White   +5 more
doaj   +1 more source

RopB protein of Rhizobium leguminosarum bv. viciae adopts amyloid state during symbiotic interactions with pea (Pisum sativum L.)

Frontiers in Plant Science, 2022
Amyloids represent protein aggregates with highly ordered fibrillar structure associated with the development of various disorders in humans and animals and involved in implementation of different vital functions in all three domains of life.
Anastasiia O. Kosolapova, Anastasiia O. Kosolapova, Mikhail V. Belousov, Mikhail V. Belousov, Maksim I. Sulatsky, Anna V. Tsyganova, Anna I. Sulatskaya, Alexander G. Bobylev, Oksana Y. Shtark, Viktor E. Tsyganov, Kirill V. Volkov, Vladimir A. Zhukov, Igor A. Tikhonovich, Igor A. Tikhonovich, Anton A. Nizhnikov, Anton A. Nizhnikov   +15 more
doaj   +1 more source

Accelerated Amyloid Beta Pathogenesis by Bacterial Amyloid FapC [PDF]

Advanced Science, 2020
AbstractThe gut–brain axis has attracted increasing attention in recent years, fueled by accumulating symptomatic, physiological, and pathological findings. In this study, the aggregation and toxicity of amyloid beta (Aβ), the pathogenic peptide associated with Alzheimer's disease (AD), seeded by FapC amyloid fragments (FapCS) of Pseudomonas aeruginosa
Ibrahim Javed, Zhenzhen Zhang, Jozef Adamcik, Nicholas Andrikopoulos, Yuhuan Li, Daniel E. Otzen, Sijie Lin, Raffaele Mezzenga, Thomas P. Davis, Feng Ding, Pu Chun Ke   +10 more
openaire   +6 more sources

Anti-Biofilm Molecules Targeting Functional Amyloids

Antibiotics, 2021
The choice of an effective therapeutic strategy in the treatment of biofilm-related infections is a significant issue. Amyloids, which have been historically related to human diseases, are now considered to be prevailing structural components of the ...
Leticia Matilla-Cuenca, Alejandro Toledo-Arana, Jaione Valle   +2 more
doaj   +1 more source

The menace within: bacterial amyloids as a trigger for autoimmune and neurodegenerative diseases. [PDF]

Curr Opin Microbiol
Elkins M, Jain N, Tükel Ç.
europepmc   +2 more sources

Promiscuous cross-seeding between bacterial amyloids promotes interspecies biofilms. [PDF]

J Biol Chem, 2012
Zhou Y, Smith D, Leong BJ, Brännström K, Almqvist F, Chapman MR.   +5 more
europepmc   +2 more sources

Microbiome or Infections: Amyloid-Containing Biofilms as a Trigger for Complex Human Diseases

Frontiers in Immunology, 2021
The human microbiota is the community of microorganisms that live upon or within their human host. The microbiota consists of various microorganisms including bacteria, fungi, viruses, and archaea; the gut microbiota is comprised mostly of bacteria. Many
Amanda L. Miller, Shingo Bessho, Kaitlyn Grando, Çagla Tükel   +3 more
doaj   +1 more source

Multifunctional Amyloids in the Biology of Gram-Positive Bacteria

Microorganisms, 2020
Since they were discovered, amyloids have proven to be versatile proteins able to participate in a variety of cellular functions across all kingdoms of life.
Ana Álvarez-Mena, Jesús Cámara-Almirón, Antonio de Vicente, Diego Romero   +3 more
doaj   +1 more source

Sequence Determinants of Bacterial Amyloid Formation [PDF]

Journal of Molecular Biology, 2008
Amyloids are proteinaceous fibers commonly associated with neurodegenerative diseases and prion-based encephalopathies. Many different polypeptides can form amyloid fibers, leading to the suggestion that amyloid is a primitive main chain-dominated structure.
Xuan, Wang, Matthew R, Chapman
openaire   +2 more sources