Results 31 to 40 of about 1,273,913 (331)

STRUCTURE AND IMMUNE ADJUVANT PROPERTIES OF CPG-D

Медицинская иммунология, 2014
Bacterial DNA, along with other bacterial pathogen-associated molecular structures, may activate both innate and adaptive immune systems. This activity is associated with by nonmethylated CpG dinucleotides, which are present in the bDNA molecule, and it ...
V. S. Polovinkina, E. Yu. Markov
doaj   +1 more source

The antimicrobial polymer PHMB enters cells and selectively condenses bacterial chromosomes [PDF]

, 2016
To combat infection and antimicrobial resistance, it is helpful to elucidate drug mechanism(s) of action. Here we examined how the widely used antimicrobial polyhexamethylene biguanide (PHMB) kills bacteria selectively over host cells.
A Gentile, B Spellberg, CE Barry, CR Messick, DJ Dwyer, EE Creppy, EF Palermo, FW O’Grady, G Muller, G Muller, G Rusciano, GS Gordon, J Portugal, JD McCool, JM Boberek, JP Armitage, L Good, LP O’Malley, M Mondhe, MA Kohanski, MJ Allen, MJ Allen, MJ Allen, N Nekhotiaeva, Nakashima, P Broxton, P Broxton, P Broxton, P Erbacher, P Gilbert, R de Vries, R Dryselius, R Firdessa, R Spurio, RF Murphy, S Amoils, S Goh, S Wessels, T Ikeda, T Ikeda, T Kornberg, VB Teif   +41 more
core   +3 more sources

High Sensitivity of Shotgun Metagenomic Sequencing in Colon Tissue Biopsy by Host DNA Depletion

Genomics, Proteomics & Bioinformatics, 2023
The high host genetic background of tissue biopsies hinders the application of shotgun metagenomic sequencing in characterizing the tissue microbiota. We proposed an optimized method that removed host DNA from colon biopsies and examined the effect on ...
Wing Yin Cheng, Wei-Xin Liu, Yanqiang Ding, Guoping Wang, Yu Shi, Eagle S.H. Chu, Sunny Wong, Joseph J.Y. Sung, Jun Yu   +8 more
doaj   +1 more source

Impact of ocean acidification on the intestinal microbiota of the marine sea bream (Sparus aurata L.) [PDF]

, 2019
Within a scenario of increasing atmospheric CO2 and ocean acidification (OA), it is highly relevant to investigate its impacts not only on fish performance but also on fish intestinal microbiome and how that reflects on host performance and health.
Banerjee, Bresolin de Souza, Brugman, Butt, Caldeira, Caldeira, Clarke, Clements, de Paula Silva, Dehler, Denev, Dimitroglou, Egerton, Esbaugh, Estruch, Farmer, Foster, Givens, Gomez, Green, Gregório, Guo, Hall, Hennige, Heuer, Heuer, Hovda, Huson, Huson, Ikeda-Ohtsubo, Jones, Kaya, Kormas, Krajmalnik-Brown, Kroeker, Llewellyn, Meehl, Meron, Merrifield, Merrifield, Mueller, Nayak, Nikouli, Pachauri, Pachauri, Parris, Piazzon, Pérez, Ramirez, Ray, Ringø, Robbins, Roeselers, Sowell, Spor, Sullam, Tarnecki, Thompson, Tirsgaard, Tran, Turnbaugh, Uren Webster, Vandenberghe, Wang, Wang, Wietz, Wright, Zhou   +67 more
core   +1 more source

DNA vaccines for bacterial infections

Immunology & Cell Biology, 1997
DNA vaccines are an exciting development in vaccine technology which may have a special role in preventing viral infections and as ‘theracines’ for cancer. Their use in preventing bacterial infections has, by comparison, been less well documented.
Strugnell, RA, Drew, D, Mercieca, J, Dinatale, S, Firez, N, Dunstan, SJ, Simmons, CP, Vadolas, J   +7 more
openaire   +5 more sources

In situ electrochemical investigation of the interaction between bacteria Xylella fastidiosa DNA and copper(II) using DNA-electrochemical biosensors

Electrochemistry Communications, 2021
New emerging bacterial plant diseases are spreading fast in different geographical regions, and effective safety measures have not been found. Xylella fastidiosa (Xf) is a Gram-negative bacterial plant pathogen classified as a priority quarantine pest ...
W.B.S. Machini, A.M. Oliveira-Brett
doaj   +1 more source

DNA waves and water [PDF]

, 2010
Some bacterial and viral DNA sequences have been found to induce low frequency electromagnetic waves in high aqueous dilutions. This phenomenon appears to be triggered by the ambient electromagnetic background of very low frequency.
A Tedeschi, C Lavallee, Del Giudice E, Del Giudice E, E Del Giudice, G Vitiello, J Aissa, L Montagnier, Landau LD, Montagnier L, Nickolaenko A P, Szent-Gyorgyi A, Voeikov VL   +12 more
core   +1 more source

Bacteria in the airways of patients with cystic fibrosis are genetically capable of producing VOCs in breath. [PDF]

, 2016
Breath contains hundreds of volatile organic compounds (VOCs), the composition of which is altered in a wide variety of diseases. Bacteria are implicated in the formation of VOCs, but the biochemical mechanisms that lead to the formation of breath VOCs ...
Blake, Donald, Bos, Lieuwe DJ, Meinardi, Simone, Whiteson, Katrine   +3 more
core   +7 more sources

Bacteria-human somatic cell lateral gene transfer is enriched in cancer samples. [PDF]

PLoS Computational Biology, 2013
There are 10× more bacterial cells in our bodies from the microbiome than human cells. Viral DNA is known to integrate in the human genome, but the integration of bacterial DNA has not been described. Using publicly available sequence data from the human
David R Riley, Karsten B Sieber, Kelly M Robinson, James Robert White, Ashwinkumar Ganesan, Syrus Nourbakhsh, Julie C Dunning Hotopp   +6 more
doaj   +1 more source

Antimicrobial activity of an iron triple helicate [PDF]

, 2009
The prevalence of antibiotic resistance has resulted in the need for new approaches to be developed to combat previously easily treatable infections.
Adair D. Richards, Albert Bolhuis, Alison Rodger, Baraldi, Boulikas, Childs, Hannon, Hannon, Kerckhoffs, Kunst, Leenhouts, Meistermann, Michael J. Hannon, Pindur, Richards, van Dijl   +15 more
core   +1 more source