Results 41 to 50 of about 3,675,539 (309)
Entropic elasticity and dynamics of the bacterial chromosome: a simulation study [PDF]
, 2017 We study the compression and extension dynamics of a DNA-like polymer interacting with non-DNA binding and DNA-binding proteins, by means of computer simulations. The geometry we consider is inspired by recent experiments probing the compressional elasticity of the bacterial nucleoid (DNA plus associated proteins), where DNA is confined into a ...
arxiv +1 more source
European Journal of Nutrition, 2018 PurposeExercise-induced changes in intestinal permeability are exacerbated in the heat. The aim of this study was to determine the effect of 14 days of bovine colostrum (Col) supplementation on intestinal cell damage (plasma intestinal fatty acid-binding
D. March +3 more
semanticscholar +1 more source
Statistical properties of DNA sequences revisited: the role of inverse bilateral symmetry in bacterial chromosomes [PDF]
, 2004 Herein it is shown that in order to study the statistical properties of DNA sequences in bacterial chromosomes it suffices to consider only one half of the chromosome because they are similar to its corresponding complementary sequence in the other half. This is due to the inverse bilateral symmetry of bacterial chromosomes.
arxiv +1 more source
Requirements for DNA-bridging proteins to act as topological barriers of the bacterial genome [PDF]
Biophysical Journal 119 (2020) 1215-1225, 2020 Bacterial genomes have been shown to be partitioned into several kilobases long chromosomal domains that are topologically independent from each other, meaning that change of DNA superhelicity in one domain does not propagate to neighbors. Both in vivo and in vitro experiments have been performed to question the nature of the topological barriers at ...
arxiv +1 more source
Journal of International Medical Research, 2020 Objective Clinical diagnostics often requires the detection of multiple bacterial species in limited clinical samples with a single DNA extraction method.
Xiaolan Li +6 more
doaj +1 more source
Role of salt valency in the switch of H-NS proteins between DNA-bridging and DNA-stiffening modes [PDF]
Biophysical Journal 114 (2018) 2317-2325, 2018 This work investigates the interactions of H-NS proteins and bacterial genomic DNA through computer simulations performed with a coarse-grained model. The model was developed specifically to study the switch of H-NS proteins from the DNA-stiffening to the DNA-bridging mode, which has been observed repeatedly upon addition of multivalent cations to the ...
arxiv +1 more source
A structural view of bacterial DNA replication
Protein Science, 2019 DNA replication mechanisms are conserved across all organisms. The proteins required to initiate, coordinate, and complete the replication process are best characterized in model organisms such as Escherichia coli.
A. Oakley
semanticscholar +1 more source
A polymer model of bacterial supercoiled DNA including structural transitions of the double helix [PDF]
, 2019 DNA supercoiling, the under or overwinding of DNA, is a key physical mechanism both participating to compaction of bacterial genomes and making genomic sequences adopt various structural forms. DNA supercoiling may lead to the formation of braided superstructures (plectonemes), or it may locally destabilize canonical B-DNA to generate denaturation ...
arxiv +1 more source
Human β‐defensin 3 increases the TLR9‐dependent response to bacterial DNA
European Journal of Immunology, 2017 Human β‐defensin 3 (hBD3) is a cationic antimicrobial peptide with potent bactericidal activity in vitro. HBD3 is produced in response to pathogen challenge and can modulate immune responses.
Sarah L McGlasson +5 more
semanticscholar +1 more source
FEBS Letters, EarlyView.In modular polyketide synthases, the dehydratase (DH) domain catalyzes the dehydration reaction of the β‐hydroxyacyl unit attached to the cognate acyl carrier protein (ACP) domain. However, it is unclear how DH interacts with ACP during the reaction. In this study, we identified DH–ACP interface residues, providing the first detailed insights into DH ...
Kaede Kotagiri +8 more
wiley +1 more source