Results 101 to 110 of about 1,488,259 (274)

Vesicle Nucleation Peptide Fusion Induced Extracellular Vesicles Are Distinct From Escherichia coli Outer Membrane Vesicles, and Provide an Enhanced Platform for Protein Production and Purification

Journal of Extracellular Vesicles
Bacterial outer membrane vesicles (OMVs) are nano‐sized, spherical structures released by Gram‐negative bacteria that play diverse roles in bacterial physiology, including communication, nutrient acquisition and host interactions. These vesicles bud from
Bree R. Streather, Tara A. Eastwood, Karen Baker, Mingzhi Liang, Alexandra E. Bailie, Tijn T. van derVelden, Lars J. C. Jeuken, Stanley W. Botchway, Lin Wang, Daniel P. Mulvihill   +9 more
doaj   +1 more source

ROS/pH‐Responsive Phenylboronic Acid–Chitosan Nanoparticles Improve Silymarin‐Mediated Hepatoprotection After Hepatectomy With Gut‐Liver Axis‐Associated Responses

Advanced Science, EarlyView.
Bioactive phenylboronic acid–chitosan nanoparticles enable responsive silymarin delivery for post‐hepatectomy liver protection. The nanoplatform integrates antioxidant and antibacterial functions, improves hepatic recovery, and is associated with coordinated shifts in gut microbiota, metabolites, cytokines, and hepatic proteomic pathways, suggesting a ...
Jinjin Tong, Chaochao Luo, Zezheng Liu, Xinyan Zhang, Daixu Jia, Yang Sun, Zhaonan Zhang, Haoran Shi, Jianfang Wang, Hua Zhang   +9 more
wiley   +1 more source

Cutibacterium acnes–Derived Extracellular Vesicles Promote Epithelial Ovarian Cancer Progression by Activating the KEAP1–NRF2 Antioxidant Pathway to Suppress Ferroptosis

Microbial Biotechnology
Bacterial extracellular vesicles are increasingly recognized as important mediators of microbe–host communication, yet their functional roles within tumour‐associated microbiota remain poorly understood.
Qifa Huang, Qi Chen, Wenjie Xiong, Yuexi Sun, Yuxiong Huang, Ang Dai, Jianying Chen, Xue Wu, Ying Jiang, Fen Wei, Qi Chen, Tingtao Chen   +11 more
doaj   +1 more source

Proteomic analysis of extracellular vesicles from Oenococcus Oeni

, 2022
Malolactic fermentation is essential for the quality of red wines and some other wine styles. This process consists in the decarboxylation of L-malic acid to L-lactic acid, increasing the pH of wine and releasing compounds with sensory impact ...
Tronchoni, J. [0000-0001-9227-2713], Mencher, A., Gonzalez, R. [0000-0001-7388-1660], Morales, P., Mejías-Ortiz, M. [0000-0001-7065-4331]   +4 more
core  

Bioenergetic Materials for Tissue Regeneration: Modulating Metabolism to Promote Cellular Anabolism

Advanced Science, EarlyView.
Bioenergetic materials (BEMs) modulate cellular metabolism to promote tissue regeneration. Their principal mechanisms of action include metabolic substrate supplementation, metabolic enzyme modulation, organelle transfer, electrical current regulation, redox homeostasis modulation, and oxygen tension modulation.
Yuchen He, Yuwen Wang, Jonathan F. Gong, Yiting Lei, Fei Jin, Weihong Zhu, Rocky S. Tuan, Zhong Alan Li   +7 more
wiley   +1 more source

Shotgun metagenomic sequencing of serum extracellular vesicle-derived DNA enables microbial profiling in urothelial carcinoma

Scientific Reports
Shotgun metagenomic sequencing provides more detailed microbial information than 16 S rRNA sequencing but requires higher cost and larger sample volumes.
Toshihiro Uemura, Atsunari Kawashima, Kentaro Jingushi, Daisuke Motooka, Takuro Saito, Shunsuke Inoguchi, Nesrine Sassi, Yuki Horibe, Akinaru Yamamoto, Tomohiro Kanaki, Yutong Liu, Masaru Tani, Akihiro Yoshimura, Toshiki Oka, Yohei Okuda, Gaku Yamamichi, Yu Ishizuya, Takuji Hayashi, Yoshiyuki Yamamoto, Taigo Kato, Koji Hatano, Kazutake Tsujikawa, Hisashi Wada, Norio Nonomura   +23 more
doaj   +1 more source

Rumen–mammary gland axis and bacterial extracellular vesicles: Exploring a new perspective on heat stress in dairy cows

Animal Nutrition
Heat stress poses a significant threat to the global livestock industry, particularly impacting dairy cows due to their higher metabolic heat production and increased susceptibility.
Qi Huang, Yang Xiao, Peng Sun
doaj   +1 more source

Neonatal Sevoflurane Exposure Induces Long‐Term Cognitive Impairment via Epigenetically Mediated MMP9 Activation and Perineuronal Net Disruption in the Hippocampal CA2

Advanced Science, EarlyView.
Hippocampal CA2 perineuronal nets ensheathing excitatory pyramidal neurons are selectively vulnerable to repeated neonatal sevoflurane exposure. Epigenetic upregulation of MMP9 via reduced H3K27me3 disrupts PNN integrity, impairs BDNF–TrkB signaling, and causes synaptic protein loss and dendritic spine deficits, leading to persistent social and spatial
Lirong Liang, Jiachen Wang, Taozhi Wang, Yanling Li, Youyi Zhao, Guanghui Hao, Peiqin Gong, Ruling Chen, Yilin Fang, Shengxi Wu, Haopeng Zhang, Hui Zhang   +11 more
wiley   +1 more source

extracellular vesicle proteome identifies markers of purity and culture conditions

, 2019
Bacteria release nano-sized extracellular vesicles (EVs) into the extracellular milieu. Bacterial EVs contain molecular cargo originating from the parent bacterium and have important roles in bacterial survival and pathogenesis.
Blenkiron, Cherie, Whitcombe, Alana, Priscila Dauros‐Singorenko, Alana Whitcombe, Swift, Simon, Jiwon Hong, Anthony Phillips, Payne, Leo, Simon Swift, Phillips, Anthony, Cherie Blenkiron, Leo Payne, Hong, Jiwon, Dauros-Singorenko, Priscila   +13 more
core   +1 more source

Decoding Biomolecular Phase Separation: From Physiological Roles to Pathological Mechanisms and Therapeutic Biomaterials Design

Advanced Science, EarlyView.
This review systematically elaborates on the mechanisms underlying physiological regulation and pathological dysregulation of biomolecular phase separation. It also summarizes advances in phase‑separation‑targeted therapeutic strategies and the design of functional biomaterials inspired by this process.
Jiawei Zhu, Jingbo Dong, Qiufang Gong, Xuejiao Song, Zhifa Shen, Chao Liang   +5 more
wiley   +1 more source