Results 61 to 70 of about 57,489 (234)

Extracellular vesicles enhance the efficacy of ceftiofur against intracellular bacterial infections

Synthetic and Systems Biotechnology
Bacterial infections pose a major threat to human health and economic stability. In particular, intracellular bacterial infections present significant clinical challenges due to antibiotic resistance and poor drug penetration.
Pingping Yuan, Shijie Zhou, Qianqian Li, Lin Li, Shaoqi Qu   +4 more
doaj   +1 more source

Negotiating in a Foreign Land: Understanding the Curious Interactions Between Intracellular Mitochondria and Internalized Nanoparticles

Advanced Materials Interfaces, EarlyView.
Therapeutic nano‐drug delivery systems interact with cellular mitochondria in a multitude of ways. While the complexity of such interactions disrupts the mitochondrial electron transport chain and increases reactive oxygen species production, thereby contributing to nanoparticle toxicity, they also present unique theranostic opportunities in diseases ...
Sourav Bhattacharjee
wiley   +1 more source

Bacterial Extracellular vesicles and their cargo

, 2021
Staphylococcus aureus and Enterococcus faecium are opportunistic pathogens that may cause diseases ranging from minor skin infection to severe blood stream infections. The emergence of methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococcal strains severely limits treatment options.
openaire   +1 more source

Extrusion Bioprinting for Wound Healing: Innovations in Functionalized Bioinks and Bioprinting Technology

Advanced Materials Technologies, EarlyView.
Extrusion‐based bioprinting (EBB) has emerged as a versatile biofabrication platform capable of precisely depositing bioinks composed of biomaterials, cells, and bioactive agents to generate patient‐specific, biomimetic skin constructs. This paper presents a state‐of‐the‐art and forward‐looking overview of EBB for wound healing, encompassing printing ...
Hien‐Phuong Le, Anh Tuan Trong Tran, Ammara Waheed, Tran Thanh Tung, Dusan Losic   +4 more
wiley   +1 more source

Toward a better understanding of the ecological roles of extracellular vesicles from plant-associated bacteria

Applied and Environmental Microbiology
Extracellular vesicles (EVs) from phytobacteria are emerging key ecological actors of plant–bacteria interactions. They can promote colonization of the host by delivering virulence factors and cell wall-degrading enzymes.
Timothée Zannis-Peyrot, Fanny Nazaret, Céline Lavire, Ludovic Vial   +3 more
doaj   +1 more source

3D‐Printed Corneal Substitutes: Materials, Fabrication, and Preclinical Progress

Advanced Materials Technologies, EarlyView.
Successful clinical translation of 3D‐printed corneal substitutes relies on the interplay between the bioink properties, cellular component, and the fabrication process. These factors influence the critical properties of the construct, including optical transparency, mechanical stability, suture retention, that ultimately govern long‐term stromal ...
Shadi Moshayedi, Ashley Vazquez, Alexander J. Choi, Dimitrios Karamichos, Jayoung Kim   +4 more
wiley   +1 more source

Gut Microbiota Regulates Systemic Inflammatory Response and Compensatory Anti‐Inflammatory Response Syndromes by Targeting PF4+ Macrophages in Acute Pancreatitis

Advanced Science, EarlyView.
ABSTRACT Acute pancreatitis (AP) begins with pancreatic local inflammation, leading to the onset of systemic inflammatory response syndrome (SIRS), followed by compensatory anti‐inflammatory response syndrome (CARS), which causes immune paralysis and higher mortality rate.
Liwei Liu, Guanqun Li, Dongxu Lu, Haoran Ding, Tianqi Lu, Yuhang Sui, Can Zhang, Yu Xie, Rui Kong, Hua Chen, Xuewei Bai, Hongtao Tan, Dongbo Xue, Xianzhi Meng, Le Li, Bei Sun   +15 more
wiley   +1 more source

Bacterial extracellular vesicles: biotechnological perspective for enhanced productivity

World Journal of Microbiology and Biotechnology
AbstractBacterial extracellular vesicles (BEVs) are non-replicative nanostructures released by Gram-negative and Gram-positive bacteria as a survival mechanism and inter- and intraspecific communication mechanism. Due to BEVs physical, biochemical, and biofunctional characteristics, there is interest in producing and using them in developing new ...
Muñoz-Echeverri, Laura M., Benavides-López, Santiago, Geiger, Otto, Trujillo-Roldán, Mauricio A., Valdez-Cruz, Norma A.   +4 more
openaire   +2 more sources

IL‐7R‐Enriched Extracellular Vesicles From the Thymus Drive Colitis via Promoting Neutrophil Extracellular Trap Formation

Advanced Science, EarlyView.
Inflammatory bowel disease (IBD) pathogenesis remains unclear. This study reveals that thymus‐originated IL‐7R‐enriched extracellular vesicles exacerbate colitis by promoting neutrophil extracellular traps via a thymus‐gut axis, uncovering an inter‐organ communication mechanism in inflammatory bowel disease pathogenesis.
Yao Liao, Yuheng Liu, Ruibing Yang, Zifeng Zhu, Junwei Wu, Dinghao Li, Jin Su, Yingxin He, Shiqi Luo, Feiyang Cao, Haiyi Deng, Lanmengxi Yang, Ling Zhong, Peiying Peng, Xinyi Wu, Chunmei Cai, Zhen Li, Yujin Wu, Shuofeng Zhu, Jie Wei, Yi Yang, Lifu Wang   +21 more
wiley   +1 more source

Capillary zone electrophoresis of bacterial extracellular vesicles: A proof of concept

Journal of Chromatography A, 2020
The extracellular vesicles (EVs) released by plant pathogens of the Pectobacterium genus were investigated. The isolates were obtained using differential centrifugation followed by filtration and were characterized in terms of total protein content and particle size distribution. The transmission electron microscopy (TEM) analysis revealed the presence
Martyna Piotrowska, Krzesimir Ciura, Michalina Zalewska, Marta Dawid, Bruna Correia, Paulina Sawicka, Bogdan Lewczuk, Joanna Kasprzyk, Laura Sola, Wojciech Piekoszewski, Bartosz Wielgomas, Krzysztof Waleron, Szymon Dziomba   +12 more
openaire   +5 more sources