Results 71 to 80 of about 1,488,259 (274)

GaSex Nanoparticles Modulate Neutrophil Function and Mitigate NET‐Driven Osteogenic Impairment in Osteomyelitis Therapy

Advanced Materials, EarlyView.
Neutrophil extracellular traps (NETs) emerge as a critical repair‐limiting factor in osteomyelitis, driving osteoblast mitochondrial dysfunction and excessive PINK1/Parkin‐mediated mitophagy. Gallium–selenium nanoparticles (GaSex) scavenge reactive oxygen species, redirect neutrophils from NETosis toward bactericidal phagocytosis, eliminate methicillin‐
Kai Ye, Xuanzhe Liu, Zifan Pei, Chenyi Jiang, Xiaofen Zhang, Lin Lin, Qihang Fang, Binyu Chen, Longxiang Shen, Liang Cheng, Peng Ding, Xianyou Zheng   +11 more
wiley   +1 more source

Life‐Like Ferrous Oxide Microspheres from Kombucha

Advanced Materials Interfaces, EarlyView.
Kombucha bacterial cellulose, sodium alginate, and ferrous nitrate self‐assemble into membrane‐enclosed iron oxide microspheres. These microspheres bud daughter vesicles, sustain 24‐h electrochemical oscillations, and filter theta‐band signals.
Panagiotis Mougkogiannis, Anna Nikolaidou, Andrew Adamatzky   +2 more
wiley   +1 more source

Cell‐Based Biohybrid Micro/Nanorobots for Biotherapy

Advanced Robotics Research, EarlyView.
This review systematically evaluates cell‐based biohybrid micro/nanorobots (CB‐BMRs), highlighting their cell selection criteria, fabrication strategies, and diverse actuation modes. Furthermore, it surveys the promising therapeutic applications of CB‐BMRs in targeted cancer, thrombosis, and inflammation treatments, while comprehensively discussing ...
Lin Wang, Chenlu Liu, Yu Zhao, Chuanhua Li, Xuyang Chen, Shixiao Ding, Lizhou Dai, Guokun Wang, Tianlong Li, Jiaxin Li, Xuejia Liu, Haocheng Wang   +11 more
wiley   +1 more source

Pneumococcal extracellular vesicles mediate horizontal gene transfer via the transformation machinery

mSphere
Bacterial cells secrete extracellular vesicles (EVs), the function of which is a matter of intense investigation. Here, we show that the EVs secreted by the human pathogen Streptococcus pneumoniae (pneumococcus) are associated with bacterial DNA on their
Sarah Werner Lass, Bailey E. Smith, Shaw Camphire, Rory A. Eutsey, Jojo A. Prentice, Saigopalakrishna S. Yerneni, Ashni Arun, Andrew A. Bridges, Jason W. Rosch, James F. Conway, Phil Campbell, N. Luisa Hiller   +11 more
doaj   +1 more source

Extracellular Vesicles

, 2022
Extracellular vesicles (EVs) are nanoscale vesicles secreted by cells that mediate horizontal cargo transport from donor to recipient cell, thereby establishing cell-cell communication and signaling.
İşlek, Zeynep, Bozkurt, Batuhan Turhan, Üçışık, Mehmet Hikmet, Şahin, Fikrettin   +3 more
core   +1 more source

Magnetically Actuated Microrobot for Drug Delivery: Current Progress and Challenges

Advanced Robotics Research, EarlyView.
Magnetically actuated microrobots are reshaping targeted drug delivery through wireless propulsion, programmable materials, and localized therapeutic release. This review examines how fabrication, body material selection, structural architecture, loading mechanisms, and imaging‐guided control converge to enable microrobotic therapies while identifying ...
Yang Yang, David J. Cappelleri
wiley   +1 more source

Bacterial extracellular vesicles exploit filopodial surfing and retraction mechanisms to reach the host cell body in an actin-dependent manner

Extracellular vesicles derived from gram-negative bacteria are nano-sized particles of different size and origin released by these microbes and are collectively called bacterial extracellular vesicles (BEVs).
Ur Rehman, Zia, Backert, Steffen, Arnqvist, Anna, Tegtmeyer, Nicole, Obi, Ikenna, Nadeem, Aftab   +5 more
core   +1 more source

Extracellular vesicles enhance the efficacy of ceftiofur against intracellular bacterial infections

Synthetic and Systems Biotechnology
Bacterial infections pose a major threat to human health and economic stability. In particular, intracellular bacterial infections present significant clinical challenges due to antibiotic resistance and poor drug penetration.
Pingping Yuan, Shijie Zhou, Qianqian Li, Lin Li, Shaoqi Qu   +4 more
doaj   +1 more source

Dissemination of Mycobacterium tuberculosis is associated to a SIGLEC1 null variant that limits antigen exchange via trafficking extracellular vesicles.

, 2021
The identification of individuals with null alleles enables studying how the loss of gene function affects infection. We previously described a non-functional variant in SIGLEC1, which encodes the myeloid-cell receptor Siglec-1/CD169 implicated in HIV-1 ...
Urrea, Victor, Martinez-Picado, Javier, Günthard, Huldrych F, McLaren, Paul J, Clotet, Bonaventura, Ong, Ruo-Yan, Julián, Esther, Monguió-Tortajada, Marta, Neyrolles, Olivier, Izquierdo-Useros, Nuria, Arias, Lilibeth, Lugo-Villarino, Geanncarlo, Luquin, Marina, Vérollet, Christel, Kontsevaya, Irina, Erkizia, Itziar, Dupont, Maeva, Borràs, Francesc E, Cardona, Pere-Joan, Cardona, Paula, Furrer, Hansjakob, Tapia, Gustavo, Telenti, Amalio, Vilaplana, Cristina, Fellay, Jacques, Crocker, Paul R, Drobniewski, Francis, Benet, Susana, Dalmau, Judith, Chojnacki, Jakub, Gálvez, Cristina   +30 more
core   +1 more source

Bacterial Extracellular vesicles and their cargo

, 2021
Staphylococcus aureus and Enterococcus faecium are opportunistic pathogens that may cause diseases ranging from minor skin infection to severe blood stream infections. The emergence of methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococcal strains severely limits treatment options.
openaire   +1 more source