Results 31 to 40 of about 2,170,676 (267)

Emerging Roles of Extracellular Vesicles in Pneumococcal Infections: Immunomodulators to Potential Novel Vaccine Candidates

Frontiers in Cellular and Infection Microbiology, 2022
The Gram-positive bacterial pathogen, Streptococcus pneumoniae is a major global health threat that kills over one million people worldwide. The pneumococcus commonly colonizes the nasopharynx asymptomatically as a commensal, but is also capable of ...
Saba Parveen, Karthik Subramanian
doaj   +1 more source

In situ imaging of bacterial outer membrane projections and associated protein complexes using electron cryo-tomography

eLife, 2021
The ability to produce outer membrane projections in the form of tubular membrane extensions (MEs) and membrane vesicles (MVs) is a widespread phenomenon among diderm bacteria.
Mohammed Kaplan, Georges Chreifi, Lauren Ann Metskas, Janine Liedtke, Cecily R Wood, Catherine M Oikonomou, William J Nicolas, Poorna Subramanian, Lori A Zacharoff, Yuhang Wang, Yi-Wei Chang, Morgan Beeby, Megan J Dobro, Yongtao Zhu, Mark J McBride, Ariane Briegel, Carrie L Shaffer, Grant J Jensen   +17 more
doaj   +1 more source

Delivery of virulence factors by bacterial membrane vesicles to mammalian host cells

, 2020
Bacterial membrane vesicles represent a universal secretion mechanism enabling both Gram-negative and Gram-positive organisms to transfer cargo to eukaryotic cells, as well as to other bacterial cells.
Nadeem, Aftab,, Wai, Sun Nyunt,, Oscarsson, Jan,   +2 more
core   +1 more source

Fusion of secretory vesicles isolated from rat liver [PDF]

, 1978
Secretory vesicles isolated from rat liver were found to fuse after exposure to Ca2+. Vescle fusion is characterized by the occurrence of twinned vesicles with a continuous cleavage plane between two vesicles in freeze-fracture electron microscopy.
Dahl, Gerhard, Dahl, G., Gratzl, Manfred   +2 more
core   +1 more source

Bacterial communication through membrane vesicles [PDF]

Bioscience, Biotechnology, and Biochemistry, 2019
ABSTRACT Bacteria can communicate through diffusible signaling molecules that are perceived by cognate receptors. It is now well established that bacterial communication regulates hundreds of genes. Hydrophobic molecules which do not diffuse in aqueous environments alone have been identified in bacterial communication, that raised the ...
openaire   +2 more sources

The functional RNA cargo of bacterial membrane vesicles [PDF]

FEMS Microbiology Letters, 2018
Bacteria secrete RNAs, some of which have effects on other cells and on other species as signalling RNAs. Prokaryotic membrane vesicles (MVs) contain a range of RNA types. The MV structure offers protection from degradation as well as receptors to facilitate delivery to target cells.
Priscila Dauros-Singorenko, Cherie Blenkiron, Anthony Phillips, Simon Swift   +3 more
openaire   +2 more sources

The Mechanism behind Bacterial Lipoprotein Release: Phenol-Soluble Modulins Mediate Toll-Like Receptor 2 Activation via Extracellular Vesicle Release from Staphylococcus aureus

mBio, 2018
The innate immune system uses Toll-like receptor (TLR) 2 to detect conserved bacterial lipoproteins of invading pathogens. The lipid anchor attaches lipoproteins to the cytoplasmic membrane and prevents their release from the bacterial cell envelope. How
Katja Schlatterer, Christian Beck, Dennis Hanzelmann, Marco Lebtig, Birgit Fehrenbacher, Martin Schaller, Patrick Ebner, Mulugeta Nega, Michael Otto, Dorothee Kretschmer, Andreas Peschel   +10 more
doaj   +1 more source

Distinct RNA profiles in subpopulations of extracellular vesicles: apoptotic bodies, microvesicles and exosomes [PDF]

, 2013
Introduction: In recent years, there has been an exponential increase in the number of studies aiming to understand the biology of exosomes, as well as other extracellular vesicles.
Szabó, Tamas G, Szabó, Tamás G., Buzás, Edit Irén, Lötvall, Jan, Jan Lötvall, Lässer, Cecilia, Dianzani, Irma, Irma Dianzani, Edit I. Buzás, Jan Lötvall, Buzás, Edit I, Maria Eldh, Crescitelli, Rossella, Kittel, Ágnes, Eldh, Maria, Rossella Crescitelli, Agnes Kittel, Tamas G. Szabó, Edit I. Buzás, Cecilia Lässer, Tamas G. Szabó, Cecilia Lässer, Eldh, Maria,, Lässer, Cecilia,, Lötvall, Jan,, Crescitelli, Rossella,   +25 more
core   +1 more source

Membrane vesicle-mediated release of bacterial RNA [PDF]

Scientific Reports, 2015
AbstractMany Gram-negative bacterial species release outer membrane vesicles (OMVs) that interact with the host by delivering virulence factors. Here, we report for the first time that RNA is among the wide variety of bacterial components that are associated with OMVs. To characterize the RNA profiles of bacterial OMVs, we performed RNA deep sequencing
Sjöström AE, Sandblad L, Uhlin BE, Wai SN   +3 more
openaire   +4 more sources

Gut-derived bacterial membrane vesicles in prediabetes: Vesicle composition dictates inflammatory properties. [PDF]

iScience
Systemic inflammation relates to the pathophysiology of metabolic diseases such as obesity or type 2 diabetes. Understanding aberrant microbiota-host interactions is essential for comprehending their pathogenesis. Gut bacteria produce bacterial membrane vesicles (bMVs) reflecting bacterial metabolism and activity.
Verbunt J, Mennens L, Jocken J, Canfora EE, Blaak EE, Savelkoul P, Stassen F.   +6 more
europepmc   +5 more sources