Results 71 to 80 of about 1,255,418 (280)

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

A resveratrol oligomer, hopeaphenol suppresses virulence activity of Pectobacterium atrosepticum via the modulation of the master regulator, FlhDC

open access: yesFrontiers in Microbiology, 2022
Pectobacterium atrosepticum (P. atrosepticum: Pba) which causes potato soft rot and blackleg is a notorious plant pathogen worldwide. Discovery of new types of antimicrobial chemicals that target specifically to virulence factors such as bacterial ...
Ji Eun Kang   +8 more
doaj   +1 more source

Bacterial Signaling and Motility: Sure Bets [PDF]

open access: yesJournal of Bacteriology, 2008
The IX International Conference on Bacterial Locomotion and Signal Transduction (BLAST IX) was held from 14 to 19 January 2007 in Laughlin, NV, a town in the Mojave Desert on the Nevada-Arizona border near old Route 66 and along the banks of the Colorado River. This area is a home to rattlesnakes,
Robert, Belas   +2 more
openaire   +2 more sources

The influence of motility on bacterial accumulation in a microporous channel

open access: yesSoft Matter, 2021
We study the transport of bacteria in a porous media modeled by a square channel containing one cylindrical obstacle via molecular dynamics simulations coupled to a lattice Boltzmann fluid.
Miru Lee   +4 more
openaire   +6 more sources

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Saturated long-chain fatty acid-producing bacteria contribute to enhanced colonic motility in rats

open access: yesMicrobiome, 2018
Background The gut microbiota is closely associated with gastrointestinal (GI) motility disorder, but the mechanism(s) by which bacteria interact with and affect host GI motility remains unclear.
Ling Zhao   +16 more
doaj   +1 more source

American Neurogastroenterology and Motility Society (ANMS) Task Force Recommendations for Resumption of Motility Laboratory Operations During the COVID-19 Pandemic [PDF]

open access: yes, 2020
The ANMS organized a Task Force for developing guidance strategies regarding re-opening of motility laboratories. This document describes how to stratify urgency of motility physiologic procedures, screen prior to the procedures, optimize personal ...
Gyawali, C. Prakash   +11 more
core  

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Potassium-mediated bacterial chemotactic response

open access: yeseLife
Bacteria in biofilms secrete potassium ions to attract free swimming cells. However, the basis of chemotaxis to potassium remains poorly understood. Here, using a microfluidic device, we found that Escherichia coli can rapidly accumulate in regions of ...
Chi Zhang, Rongjing Zhang, Junhua Yuan
doaj   +1 more source

Swimming Motility, a Virulence Trait of Ralstonia solanacearum, Is Regulated by FlhDC and the Plant Host Environment

open access: yesMolecular Plant-Microbe Interactions, 2004
Swimming motility allows the bacterial wilt pathogen Ralstonia solanacearum to efficiently invade and colonize host plants. However, the bacteria are essentially nonmotile once inside plant xylem vessels.
Julie Tans-Kersten   +2 more
doaj   +1 more source

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