Results 241 to 250 of about 158,347 (278)

Benchmarking of five NGS mapping tools for the reference alignment of bacterial outer membrane vesicles-associated small RNAs. [PDF]

Front Microbiol
Banović Đeri B, Nešić S, Vićić I, Samardžić J, Nikolić D.   +4 more
europepmc   +1 more source

In Situ High‐Resolution Imaging of Live Treponema pallidum Using Catalyst‐Free Bioorthogonal Strategy

Aggregate, EarlyView.
Schematic illustration of labeling live Treponema pallidum using an activated alkyne‐modified AIE chromophore via catalyst‐free bioorthogonal reaction. ABSTRACT Treponema pallidum (T. pallidum) causes syphilis, a sexually transmitted disease that leads to multi‐organ complications and even death. The lack of technology for tracing live T.
Jialin Huang, Judun Zheng, Xu Chen, Weiqiang Lin, Minghai Zhao, Qiulin Xie, Zeyu Liu, Dong Wang, Ben Zhong Tang, Yuhui Liao   +9 more
wiley   +1 more source

Animal models of lung cancer: Phenotypic comparison of different animal models of lung cancer and their application in the study of mechanisms

Animal Models and Experimental Medicine, EarlyView.
Grafts used to construct lung cancer animal models come from various sources, primarily cell lines, patient‐derived tumor tissues, and circulating tumor cells. Based on the sources of grafts and research objectives, lung cancer animal models can be categorized into several types: chemical‐induced models, orthotopic transplantation models, heterotopic ...
Zixuan Yang, Xianbin Zhao, Lili Tan, Pingxinyi Que, Tong Zhao, Wei Huang, Dejiao Yao, Songqi Tang   +7 more
wiley   +1 more source

Multiple low dose streptozotocin‐induced diabetes as a model for studying autoimmune diabetes in humans

Animal Models and Experimental Medicine, EarlyView.
Multiple low dose streptozotocin‐induced diabetes is a valuable animal model of diabetes type 1. It should be improved by further research on autoantigens, microbiota and mucosal immune cells from the gut, but also from other organs. Abstract The autoimmune response directed against pancreatic β cells is the most essential pathogenic process in type 1 ...
Ivan Koprivica, Suzana Stanisavljević, Dragica Mićanović, Ivana Stojanović, Đorđe Miljković   +4 more
wiley   +1 more source

Metal ions-anchored bacterial outer membrane vesicles for enhanced ferroptosis induction and immune stimulation in targeted antitumor therapy. [PDF]

J Nanobiotechnology
Sun Y, Ma YY, Shangguan S, Ruan Y, Bai T, Xue P, Zhuang H, Cao W, Cai H, Tang E, Wu Z, Yang M, Zeng Y, Sun J, Fan Y, Zeng X, Yan S.   +16 more
europepmc   +1 more source

Extracellular Vesicles in Calcium Oxalate Nephrolithiasis: Emerging Biomarkers and Therapeutic Potential

Advanced NanoBiomed Research, EarlyView.
Kidney stones cause significant pain and healthcare costs. Current prediction, diagnosis, and treatment options are limited. Extracellular vesicles (EVs), rich in proteins, lipids, and nucleic acids, offer a promising solution. This review explores the roles of EVs in kidney stone management, highlighting their potential as biomarkers and therapeutic ...
Wang Zhu, Xu Changzhi, Deng Qiong, Liang Hui   +3 more
wiley   +1 more source

Lipopolysaccharide lateral mobility in the Gram-negative bacterial outer membrane is confined and governed by interactions within the conserved Lipid A anchor

Nabarro J, Leaman RM, Lenton S, Mantion L, Spears RJ, Coles MC, Pushkin DO, Fascione MA, Baumann CG.   +8 more
europepmc   +1 more source

Multiomics integration for the function of bacterial outer membrane vesicles in the larval settlement of marine sponges. [PDF]

Front Microbiol
Zhang B, Jia C, Li M, Wang K, Chen J, Zhao J.   +5 more
europepmc   +1 more source

Gold Nanoclusters as Smart Nanoplatforms for Targeted Cancer Therapy

Advanced NanoBiomed Research, EarlyView.
A folic acid‐targeted gold nanocluster platform is developed for tumor‐specific delivery and radiofrequency (RF)‐triggered release of doxorubicin. Enhanced uptake, nuclear localization, and therapeutic efficacy are confirmed in 2D and 3D spheroid models.
Samad Mussa Farkhani, David Rudd, Helmut Thissen, Muhammad A. Ali, Mehmet Yuce, Anna Cifuentes‐Rius, Nicolas H. Voelcker   +6 more
wiley   +1 more source

Activation of a Secondary‐Messenger Receptor via Allosteric Modulation of a Dynamic Conformational Ensemble

Angewandte Chemie International Edition, EarlyView.
Intrinsically disordered loops within globular protein domains have long escaped structural biology. Here, Söldner et al. show that despite this disorder, an allosteric modulation is exerted in a secondary‐messenger receptor by binding of its secondary messenger.
Benedikt Söldner, Himanshu Singh, Elias Akoury, Gregor Witte, Rasmus Linser   +4 more
wiley   +1 more source