Outer membrane permeabilization is an essential step in the killing of gram-negative bacteria by the lectin RegIIIβ. [PDF]
PLoS ONE, 2013 The C-type lectin RegIIIβ can kill certain Gram-positive and Gram-negative bacteria. The susceptibility of S. Typhimurium depends on the bacterial growth phase, i.e., bacteria from the logarithmic growth phase do bind RegIIIβ and are subsequently killed.
Tsuyoshi Miki, Wolf-Dietrich Hardt
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HELICOBACTER PYLORI OIPA VIRULENCE GENE AS A MOLECULAR MARKER OF SEVERE GASTROPATHIES [PDF]
Arquivos de GastroenterologiaBackground: Helicobacter pylori is an etiologic agent of gastroduodenal diseases. The microorganism, considered a type I carcinogen, affects about 50% of the global population. H.
Diogo Nery MACIEL +4 more
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Role of Outer Membrane Vesicles in Bacterial Physiology and Host Cell Interactions
Infectious Microbes & Diseases, 2020 . Outer membrane vesicles (OMVs) are spherical particles shed from the outer membrane of Gram-negative bacteria, which contain the typical components present in the outer membrane, although enrichment of specific molecules may occur, and furthermore a ...
Lingyu Gao +2 more
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Subdominant antigens in bacterial vaccines: AM779 is subdominant in the Anaplasma marginale outer membrane vaccine but does not associate with protective immunity. [PDF]
PLoS ONE, 2012 Identification of specific antigens responsible for the ability of complex immunogens to induce protection is a major goal in development of bacterial vaccines.
Saleh M Albarrak +8 more
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Outer Membrane Vesicles as Mediators of Plant–Bacterial Interactions
Frontiers in Microbiology, 2022 Plants have co-evolved with diverse microorganisms that have developed different mechanisms of direct and indirect interactions with their host. Recently, greater attention has been paid to a direct “message” delivery pathway from bacteria to plants ...
Małgorzata Rudnicka +5 more
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Langmuir Monolayers of Bacterial Outer Membranes [PDF]
Biophysical Journal, 2013 The increase of Gram-negative bacteria super-resistant to antibiotics is a major problem in medicine. These bacteria possess a double membrane system, with the external leaflet of the outer membrane composed of lipopolyssaccharides (LPS) that act as the first barrier to drugs.
Nobre, Thatyane M. +3 more
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Knockout of mlaA increases Escherichia coli virulence in a silkworm infection model
PLoS ONE, 2022 The mlaA gene encodes a lipoprotein to maintain an outer membrane lipid asymmetry in gram-negative bacteria. Although the role of mlaA in bacterial virulence has been studied in several bacterial species, there are no reports of its role in E.
Haruka Nasu +3 more
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Surface Polysaccharide Extraction and Quantification
Bio-Protocol, 2013 Gram-negative bacterial cells possess two membranes - the inner cytoplasmic membrane and the outer membrane. The two membranes are distinct in their composition; the inner membrane is composed of a phospholipid bilayer, whereas the outer membrane (OM) is
Cedric Brimacombe, John Beatty
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Molecular imaging of bacterial outer membrane vesicles based on bacterial surface display
Scientific Reports, 2023 The important roles of bacterial outer membrane vesicles (OMVs) in various diseases and their emergence as a promising platform for vaccine development and targeted drug delivery necessitates the development of imaging techniques suitable for quantifying
Dávid Szöllősi +24 more
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Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source