Results 21 to 30 of about 465,571 (364)
Versatility of bacterial outer membrane vesicles in regulating intestinal homeostasis
Science Advances, 2023 Outer membrane vesicles (OMVs) play vital roles in bacterial communication both intraspecifically and interspecifically. However, extracellular mechanisms of gut microbiota–derived OMVs in the intestine remain poorly understood. Here, we report that OMVs
Xinyue Wang +7 more
semanticscholar +1 more source
Nature Communications, 2023 Efferocytosis inhibition is emerging as an attractive strategy for antitumor immune therapy because of the subsequent leak of abundant immunogenic contents.
Wanru Zhuang +8 more
semanticscholar +1 more source
Nature Communications, 2023 Oncolytic adenoviruses (Ads)-mediated anti-tumor activity is related to virus-promoted autophagy in tumor cells. Here the authors describe the design of a microbial nanocomposite based on Ads-encapsulated in bacterial outer membrane vesicles to promote ...
Weiyue Ban +10 more
semanticscholar +1 more source
TonB-Dependent Transport Across the Bacterial Outer Membrane.
Annual Review of Microbiology, 2023 TonB-dependent transporters (TBDTs) are present in all gram-negative bacteria and mediate energy-dependent uptake of molecules that are too scarce or large to be taken up efficiently by outer membrane (OM) diffusion channels. This process requires energy
Augustinas Silale, B. van den Berg
semanticscholar +1 more source
PLoS Pathogens, 2022 As pathogenic bacteria become increasingly resistant to antibiotics, antimicrobials with mechanisms of action distinct from current clinical antibiotics are needed.
Jamie L Dombach +5 more
doaj +1 more source
Bacterial Outer Membrane Vesicles: From Discovery to Applications.
Annual Review of Microbiology, 2021 Secretion of cellular components across the plasma membrane is an essential process that enables organisms to interact with their environments. Production of extracellular vesicles in bacteria is a well-documented but poorly understood process.
M. G. Sartorio +3 more
semanticscholar +1 more source
Outer membrane vesicles: A bacterial-derived vaccination system
Frontiers in Microbiology, 2022 Outer membrane vesicles (OMVs) are non-living spherical nanostructures that derive from the cell envelope of Gram-negative bacteria. OMVs are important in bacterial pathogenesis, cell-to-cell communication, horizontal gene transfer, quorum sensing, and ...
Linda A. Lieberman
doaj +1 more source
The outer membrane phospholipase A is essential for membrane integrity and type III secretion in Shigella flexneri [PDF]
Open Biology, 2016 Outer membrane phospholipase A (OMPLA) is an enzyme located in the outer membrane of Gram-negative bacteria. OMPLA exhibits broad substrate specificity, and some of its substrates are located in the cellular envelope.
Xia Wang +10 more
doaj +1 more source
Bacterial outer membrane vesicles as a candidate tumor vaccine platform
Frontiers in Immunology, 2022 Cancer represents a serious concern for human life and health. Due to drug resistance and the easy metastasis of tumors, there is urgent need to develop new cancer treatment methods beyond the traditional radiotherapy, chemotherapy, and surgery ...
Shuming Wang +10 more
semanticscholar +1 more source
Microbiology Spectrum, 2023 Pseudomonas aeruginosa is a ubiquitous opportunistic pathogen that can cause a variety of acute and chronic infections. The bacterium is highly resistant to numerous antibiotics.
Xiaoya Wei +9 more
doaj +1 more source