Results 91 to 100 of about 268,169 (218)

Outer membrane permeabilization by the membrane attack complex sensitizes Gram-negative bacteria to antimicrobial proteins in serum and phagocytes.

PLoS Pathogens, 2021
Infections with Gram-negative bacteria form an increasing risk for human health due to antibiotic resistance. Our immune system contains various antimicrobial proteins that can degrade the bacterial cell envelope.
Dani A C Heesterbeek, Remy M Muts, Vincent P van Hensbergen, Pieter de Saint Aulaire, Tom Wennekes, Bart W Bardoel, Nina M van Sorge, Suzan H M Rooijakkers   +7 more
doaj   +1 more source

In vivo testing of novel vaccine prototypes against Actinobacillus pleuropneumoniae [PDF]

, 2018
Actinobacillus pleuropneumoniae (A. pleuropneumoniae) is a Gram-negative bacterium that represents the main cause of porcine pleuropneumonia in pigs, causing significant economic losses to the livestock industry worldwide. A.
A Hensel, A Kulp, A Maas, A Menzel, Alannah Deeney, Anders Miki Bojesen, Andrew Rycroft, B Kim, BS Collins, Cathrine Ørskov, Cyrielle Fougeroux, D Hoeltig, D Reimer, DJ Chen, E Negrete-Abascal, E Negrete-Abascal, F Antenucci, F Xie, Fabio Antenucci, FM Aarestrup, G Vernikos, H Bosch van den, H Huang, H Huang, H Sanders, I Overbeke Van, J Frey, J Frey, JL Jobert, JQ Tumamao, JT Bossé, JT Bossé, K Chiers, K Chiers, K Klitgaard, L Pol van der, L Sadilkova, M Hagberg, M Pritsch, M Ramjeet, M Shao, M Torremorell, M Vanni, MJ Jacobsen, NL Price, OG González, PC Hannan, Peter Johannes Holst, R Acevedo, R Sarkozi, S Thrane, Sacristán R Pozo Del, SE Pors, WC Losinger, X Xie, Y Zhou   +55 more
core   +4 more sources

Folding of a bacterial outer membrane protein during passage through the periplasm [PDF]

The EMBO Journal, 1997
The transport of bacterial outer membrane proteins to their destination might be either a one-step process via the contact zones between the inner and outer membrane or a two-step process, implicating a periplasmic intermediate that inserts into the membrane. Furthermore, folding might precede insertion or vice versa.
Elaine F Eppens, Jan Tommassen, Nico Nouwen   +2 more
openaire   +3 more sources

Exploring bacterial outer membrane barrier to combat bad bugs

Infection and Drug Resistance, 2017
Ishan Ghai,1 Shashank Ghai2 1School of Engineering and Life Sciences, Jacobs University, Bremen, 2Leibniz University, Hannover, Germany Abstract: One of the main fundamental mechanisms of antibiotic resistance in Gram-negative bacteria comprises an ...
Ghai I, Ghai S
doaj  

Rapid evolution of the sequences and gene repertoires of secreted proteins in bacteria.

PLoS ONE, 2012
Proteins secreted to the extracellular environment or to the periphery of the cell envelope, the secretome, play essential roles in foraging, antagonistic and mutualistic interactions.
Teresa Nogueira, Marie Touchon, Eduardo P C Rocha   +2 more
doaj   +1 more source

Analysis of proteome adaptation reveals a key role of the bacterial envelope in starvation survival

Molecular Systems Biology, 2022
Bacteria reorganize their physiology upon entry to stationary phase. What part of this reorganization improves starvation survival is a difficult question because the change in physiology includes a global reorganization of the proteome, envelope, and ...
Severin Schink, Constantin Ammar, Yu‐Fang Chang, Ralf Zimmer, Markus Basan   +4 more
doaj   +1 more source

The pio Operon Is Essential for Phototrophic Fe(II) Oxidation in Rhodopseudomonas palustris TIE-1 [PDF]

, 2006
Phototrophic Fe(II)-oxidizing bacteria couple the oxidation of ferrous iron [Fe(II)] to reductive CO2 fixation by using light energy, but until recently, little has been understood about the molecular basis for this process. Here we report the discovery,
Jiao, Yongqin, Newman, Dianne K.
core   +4 more sources

Gibbs motif sampling: Detection of bacterial outer membrane protein repeats [PDF]

Protein Science, 1995
AbstractThe detection and alignment of locally conserved regions (motifs) in multiple sequences can provide insight into protein structure, function, and evolution. A new Gibbs sampling algorithm is described that detects motif‐encoding regions in sequences and optimally partitions them into distinct motif models; this is illustrated using a set of ...
Jun Liu, Charles E. Lawrence, Charles E. Lawrence, Andrew F. Neuwald   +3 more
openaire   +2 more sources

Crosstalk between Helicobacter pylori and gastric epithelial cells is impaired by docosahexaenoic acid.

PLoS ONE, 2013
H. pylori colonizes half of the world's population leading to gastritis, ulcers and gastric cancer. H. pylori strains resistant to antibiotics are increasing which raises the need for alternative therapeutic approaches.
Marta Correia, Valérie Michel, Hugo Osório, Meriem El Ghachi, Mathilde Bonis, Ivo G Boneca, Hilde De Reuse, António A Matos, Pascal Lenormand, Raquel Seruca, Ceu Figueiredo, Jose Carlos Machado, Eliette Touati   +12 more
doaj   +1 more source

Pathogen-host reorganization during Chlamydia invasion revealed by cryo-electron tomography [PDF]

, 2014
Invasion of host cells is a key early event during bacterial infection, but the underlying pathogen-host interactions are yet to be fully visualised in three-dimensional detail.
Hackstadt T., Louis C., Matsumoto A., Matsumoto A., Newhall W.J., Scidmore M.A., Ward M.E.   +6 more
core   +1 more source