Antimicrobial peptides (AMPs) are a unique and diverse group of molecules endowed with a broad spectrum of antibiotics properties that are being considered as new alternative therapeutic agents.
Angela Di Somma+13 more
doaj +1 more source
TonB-Dependent Transport Across the Bacterial Outer Membrane.
TonB-dependent transporters (TBDTs) are present in all gram-negative bacteria and mediate energy-dependent uptake of molecules that are too scarce or large to be taken up efficiently by outer membrane (OM) diffusion channels. This process requires energy
Augustinas Silale, B. van den Berg
semanticscholar +1 more source
Subdominant antigens in bacterial vaccines: AM779 is subdominant in the Anaplasma marginale outer membrane vaccine but does not associate with protective immunity. [PDF]
Identification of specific antigens responsible for the ability of complex immunogens to induce protection is a major goal in development of bacterial vaccines.
Saleh M Albarrak+8 more
doaj +1 more source
Omp85, an evolutionarily conserved bacterial protein involved in outer-membrane-protein assembly
The insertion of proteins into membranes generally requires the assistance of membrane proteins. A protein, designated Omp85 in Neisseria meningitidis, was shown to be required for the assembly of bacterial outer-membrane proteins. The protein is essential for the viability of the bacteria and is ubiquitous among Gram-negative bacteria. Omp85 depletion
Romé Voulhoux, Jan Tommassen
openalex +5 more sources
Pattern of amino acid substitutions in transmembrane domains of β-barrel membrane proteins for detecting remote homologs in bacteria and mitochondria. [PDF]
β-barrel membrane proteins play an important role in controlling the exchange and transport of ions and organic molecules across bacterial and mitochondrial outer membranes.
David Jimenez-Morales, Jie Liang
doaj +1 more source
HELICOBACTER PYLORI OIPA VIRULENCE GENE AS A MOLECULAR MARKER OF SEVERE GASTROPATHIES [PDF]
Background: Helicobacter pylori is an etiologic agent of gastroduodenal diseases. The microorganism, considered a type I carcinogen, affects about 50% of the global population. H.
Diogo Nery MACIEL+4 more
doaj +1 more source
Super-Resolution Imaging of Protein Secretion Systems and the Cell Surface of Gram-Negative Bacteria
Gram-negative bacteria have a highly evolved cell wall with two membranes composed of complex arrays of integral and peripheral proteins, as well as phospholipids and glycolipids.
Sachith D. Gunasinghe+4 more
doaj +1 more source
Outer membrane biogenesis in Helicobacter pylori: A deviation from the paradigm
The bacterial pathogen Helicobacter pylori is capable of colonizing the gastric mucosa of the human stomach using a variety of factors associated with or secreted from its outer membrane (OM).
George W. Liechti, Joanna B. Goldberg
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Stress-Responsive Periplasmic Chaperones in Bacteria
Periplasmic proteins are involved in a wide range of bacterial functions, including motility, biofilm formation, sensing environmental cues, and small-molecule transport. In addition, a wide range of outer membrane proteins and proteins that are secreted
Hyunhee Kim+4 more
doaj +1 more source
Effect of Energy Metabolism on Protein Motility in the Bacterial Outer Membrane [PDF]
We demonstrate the energy dependence of the motion of a porin, the lambda-receptor, in the outer membrane of living Escherichia coli by single molecule investigations. By poisoning the bacteria with arsenate and azide, the bacterial energy metabolism was stopped.
Ryder, Tabita Winther+4 more
openaire +4 more sources