Results 31 to 40 of about 142,532 (273)

Comprehensive in silico prediction and analysis of chlamydial outer membrane proteins reflects evolution and life style of the Chlamydiae

open access: yesBMC Genomics, 2009
Background Chlamydiae are obligate intracellular bacteria comprising some of the most important bacterial pathogens of animals and humans. Although chlamydial outer membrane proteins play a key role for attachment to and entry into host cells, only few ...
Myers Garry   +5 more
doaj   +1 more source

Dissecting Escherichia coli outer membrane biogenesis using differential proteomics. [PDF]

open access: yesPLoS ONE, 2014
The cell envelope of Gram-negative bacteria is a complex multi-layered structure comprising an inner cytoplasmic membrane and an additional asymmetric lipid bilayer, the outer membrane, which functions as a selective permeability barrier and is essential
Alessandra M Martorana   +7 more
doaj   +1 more source

Not All Bacterial Outer-Membrane Proteins Are β-Barrels [PDF]

open access: yesMicroPubl Biol
The discovery of Wza, an octomeric helical barrel integral bacterial outer-transmembrane protein, has challenged the widely held understanding that all integral outer-membrane proteins of Gram-negative bacteria are closed β-barrels composed of transmembrane β- strands.
Heido J   +4 more
europepmc   +3 more sources

Gibbs motif sampling: Detection of bacterial outer membrane protein repeats [PDF]

open access: yesProtein Science, 1995
AbstractThe detection and alignment of locally conserved regions (motifs) in multiple sequences can provide insight into protein structure, function, and evolution. A new Gibbs sampling algorithm is described that detects motif‐encoding regions in sequences and optimally partitions them into distinct motif models; this is illustrated using a set of ...
A F, Neuwald, J S, Liu, C E, Lawrence
openaire   +2 more sources

Combinatorial Antimicrobial Efficacy and Mechanism of Linalool Against Clinically Relevant Klebsiella pneumoniae

open access: yesFrontiers in Microbiology, 2021
Antibiotic–adjuvant combinatory therapy serves as a viable treatment option in addressing antibiotic resistance in the clinical setting. This study was carried out to assess and characterize the adjuvant potential and mode of action of linalool against ...
Shun-Kai Yang   +7 more
doaj   +1 more source

Antimicrobial activity and mode of action of terpene linalyl anthranilate against carbapenemase-producing Klebsiella pneumoniae

open access: yesJournal of Pharmaceutical Analysis, 2021
Mining of plant-derived antimicrobials is the major focus at current to counter antibiotic resistance. This study was conducted to characterize the antimicrobial activity and mode of action of linalyl anthranilate (LNA) against carbapenemase-producing ...
Shun-Kai Yang   +5 more
doaj   +1 more source

Membrane Protein Simulations: Ion Channels And Bacterial Outer Membrane Proteins

open access: yes, 2003
Publisher Summary The chapter focuses on two classes that have been investigated by a number of research groups—namely, ion channels and bacterial outer membrane proteins—rather than attempt to cover all simulations of membrane proteins. Ion channels play a key role in the electrical activity of cells of the nervous system. However, channels are also
Domene, Carmen   +2 more
openaire   +3 more sources

Insertion of proteins and lipopolysaccharide into the bacterial outer membrane [PDF]

open access: yesPhilosophical Transactions of the Royal Society B: Biological Sciences, 2017
The bacterial outer membrane contains phospholipids in the inner leaflet and lipopolysaccharide (LPS) in the outer leaflet. Both proteins and LPS must be frequently inserted into the outer membrane to preserve its integrity. The protein complex that inserts LPS into the outer membrane is called LptDE, and consists of an integral membrane protein, LptD,
Istvan Botos   +2 more
openaire   +2 more sources

The Landscape of Pseudomonas aeruginosa Membrane-Associated Proteins

open access: yesCells, 2020
Background: Pseudomonas aeruginosa cell envelope-associated proteins play a relevant role in infection mechanisms. They can contribute to the antibiotic resistance of the bacterial cells and be involved in the interaction with host cells.
Sara Motta   +7 more
doaj   +1 more source

Mucin adsorbed by E. coli can affect neutrophil activation in vitro

open access: yesFEBS Open Bio, 2020
Bacteria colonizing human intestine adhere to the gut mucosa and avoid the innate immune system. We previously demonstrated that Escherichia coli isolates can adsorb mucin from a diluted solution in vitro.
Elena Mikhalchik   +11 more
doaj   +1 more source

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