Pattern of amino acid substitutions in transmembrane domains of β-barrel membrane proteins for detecting remote homologs in bacteria and mitochondria. [PDF]
β-barrel membrane proteins play an important role in controlling the exchange and transport of ions and organic molecules across bacterial and mitochondrial outer membranes.
David Jimenez-Morales, Jie Liang
doaj +1 more source
Exploring the biochemistry at the extracellular redox frontier of bacterial mineral Fe(III) respiration [PDF]
Many species of the bacterial Shewanella genus are notable for their ability to respire in anoxic environments utilizing insoluble minerals of Fe(III) and Mn(IV) as extracellular electron acceptors.
Andrew J. Gates +27 more
core +3 more sources
Detection of the babA2 adhesin gene in Helicobacter pylori clinical isolates and correlation with upper gastrointestinal diseases [PDF]
Helicobacter pylori is an oncobacteria that infects more than half of the world’s population. Adhesins are virulence factors that are essential for the microorganism to bind to the gastric mucosa, such as the BabA adhesion protein, which is associated ...
DIOGO NERY MACIEL +5 more
doaj +1 more source
Super-Resolution Imaging of Protein Secretion Systems and the Cell Surface of Gram-Negative Bacteria
Gram-negative bacteria have a highly evolved cell wall with two membranes composed of complex arrays of integral and peripheral proteins, as well as phospholipids and glycolipids.
Sachith D. Gunasinghe +4 more
doaj +1 more source
In vitro and in vivo screening for novel essential cell-envelope proteins in Pseudomonas aeruginosa [PDF]
The Gram-negative bacterium Pseudomonas aeruginosa represents a prototype of multi-drug resistant opportunistic pathogens for which novel therapeutic options are urgently required.
Bragonzi, Alessandra +5 more
core +1 more source
Biochemical analysis of TssK, a core component of the bacterial Type VI secretion system, reveals distinct oligomeric states of TssK and identifies a TssK–TssFG subcomplex [PDF]
Gram-negative bacteria use the Type VI secretion system (T6SS) to inject toxic proteins into rival bacteria or eukaryotic cells. However, the mechanism of the T6SS is incompletely understood. In the present study, we investigated a conserved component of
Alan R. Prescott +60 more
core +3 more sources
Outer membrane biogenesis in Helicobacter pylori: A deviation from the paradigm
The bacterial pathogen Helicobacter pylori is capable of colonizing the gastric mucosa of the human stomach using a variety of factors associated with or secreted from its outer membrane (OM).
George W. Liechti, Joanna B. Goldberg
doaj +1 more source
Targeting bacterial outer-membrane remodelling to impact antimicrobial drug resistance.
The cell envelope is essential for survival and adaptation of bacteria. Bacterial membrane proteins include the major porins that mediate the influx of nutrients and several classes of antimicrobial drugs.
Natalia C Rosas, T. Lithgow
semanticscholar +1 more source
The cytochrome c import pathway differs markedly from the general route taken by the majority of other imported proteins, which is characterized by the import involvement of namely, surface receptors, the general insertion protein (GIP), contact sites ...
Berkout +68 more
core +1 more source
Biological membranes consist of two leaflets of phospholipid molecules that form a bilayer, each leaflet comprising a distinct lipid composition. This asymmetry is created and maintained in vivo by dedicated biochemical pathways, but difficulties in ...
Jonathan M Machin +3 more
semanticscholar +1 more source

