Results 41 to 50 of about 268,169 (218)

Comprehensive in silico prediction and analysis of chlamydial outer membrane proteins reflects evolution and life style of the Chlamydiae

BMC Genomics, 2009
Background Chlamydiae are obligate intracellular bacteria comprising some of the most important bacterial pathogens of animals and humans. Although chlamydial outer membrane proteins play a key role for attachment to and entry into host cells, only few ...
Myers Garry, Rattei Thomas, Tischler Patrick, Heinz Eva, Wagner Michael, Horn Matthias   +5 more
doaj   +1 more source

Dissecting Escherichia coli outer membrane biogenesis using differential proteomics. [PDF]

PLoS ONE, 2014
The cell envelope of Gram-negative bacteria is a complex multi-layered structure comprising an inner cytoplasmic membrane and an additional asymmetric lipid bilayer, the outer membrane, which functions as a selective permeability barrier and is essential
Alessandra M Martorana, Sara Motta, Dario Di Silvestre, Federica Falchi, Gianni Dehò, Pierluigi Mauri, Paola Sperandeo, Alessandra Polissi   +7 more
doaj   +1 more source

Not All Bacterial Outer-Membrane Proteins Are β-Barrels [PDF]

MicroPubl Biol
The discovery of Wza, an octomeric helical barrel integral bacterial outer-transmembrane protein, has challenged the widely held understanding that all integral outer-membrane proteins of Gram-negative bacteria are closed β-barrels composed of transmembrane β- strands.
Heido J, Keng S, Poyrazoglu H, Priyam E, Jayasinghe S.   +4 more
europepmc   +3 more sources

Bacterial porin disrupts mitochondrial membrane potential and sensitizes host cells to apoptosis [PDF]

, 2009
The bacterial PorB porin, an ATP-binding beta-barrel protein of pathogenic Neisseria gonorrhoeae, triggers host cell apoptosis by an unknown mechanism. PorB is targeted to and imported by host cell mitochondria, causing the breakdown of the mitochondrial
A Degterev, A Müller, A Müller, AE Deghmane, Anke Harsman, B Shanmugavadivu, Dirk Günther, DM Walther, DR Voelker, E Gottlieb, E Gottlieb, Elke A. Dian-Lothrop, Eva Hauf, FJ Bauer, FJ Castora, G Kroemer, G Schatz, Hank Steven Seifert, I Guilvout, IE Gentle, Ines Herrmann, J Song, JE Chipuk, JF Weel, Joachim Rassow, K Hill, Katharina Ross, Krishnaraj Rajalingam, L Scorrano, LA Pon, LC Armstrong, LM Loew, M Meinecke, MC Wei, Michael Meinecke, MP Bos, N Bolender, N Pfanner, N Wiedemann, N Wiedemann, O Kepp, O Kepp, Oliver Kepp, P Massari, P Massari, P Mueller, R Voulhoux, RD Taylor, Richard Wagner, Robert Hurwitz, RP Zahedi, S Desagher, S Kutik, S Makino, SA Paschen, SA Paschen, T Krimmer, T Rudel, Thomas Rudel, V Kozjak, V Kozjak-Pavlovic, V Robert, Vera Kozjak-Pavlovic, Volker Brinkmann, W Neupert   +64 more
core   +4 more sources

Oxidative protein biogenesis and redox regulation in the mitochondrial intermembrane space [PDF]

, 2016
Mitochondria are organelles that play a central role in cellular metabolism, as they are responsible for processes such as iron/sulfur cluster biogenesis, respiration and apoptosis.
MacPherson, Lisa, Manganas, Phanee, Tokatlidis, Kostas   +2 more
core   +1 more source

Folding of a bacterial integral outer membrane protein is initiated in the periplasm [PDF]

Nature Communications, 2017
AbstractThe Bam complex promotes the insertion of β-barrel proteins into the bacterial outer membrane, but it is unclear whether it threads β-strands into the lipid bilayer in a stepwise fashion or catalyzes the insertion of pre-folded substrates.
Harris D. Bernstein, Janine H. Peterson, Rakesh Sikdar, D. Eric Anderson   +3 more
openaire   +4 more sources

Combinatorial Antimicrobial Efficacy and Mechanism of Linalool Against Clinically Relevant Klebsiella pneumoniae

Frontiers in Microbiology, 2021
Antibiotic–adjuvant combinatory therapy serves as a viable treatment option in addressing antibiotic resistance in the clinical setting. This study was carried out to assess and characterize the adjuvant potential and mode of action of linalool against ...
Shun-Kai Yang, Khatijah Yusoff, Khatijah Yusoff, Mokrish Ajat, Chien-Yeong Wee, Polly-Soo-Xi Yap, Swee-Hua-Erin Lim, Kok-Song Lai   +7 more
doaj   +1 more source

Spirochetal Lipoproteins and Immune Evasion. [PDF]

, 2017
Spirochetes are a major threat to public health. However, the exact pathogenesis of spirochetal diseases remains unclear. Spirochetes express lipoproteins that often determine the cross talk between the host and spirochetes.
Boyadjian, Ani, Christodoulides, Alexei, Kelesidis, Theodoros   +2 more
core   +1 more source

Assembly of β-barrel proteins into bacterial outer membranes

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2014
Membrane proteins with a β-barrel topology are found in the outer membranes of Gram-negative bacteria and in the plastids and mitochondria of eukaryotic cells. The assembly of these membrane proteins depends on a protein folding reaction (to create the barrel) and an insertion reaction (to integrate the barrel within the outer membrane).
Selkrig, Joel, Leyton, Denisse, Webb, Chaille T, Lithgow, Trevor   +3 more
openaire   +4 more sources

Antimicrobial activity and mode of action of terpene linalyl anthranilate against carbapenemase-producing Klebsiella pneumoniae

Journal of Pharmaceutical Analysis, 2021
Mining of plant-derived antimicrobials is the major focus at current to counter antibiotic resistance. This study was conducted to characterize the antimicrobial activity and mode of action of linalyl anthranilate (LNA) against carbapenemase-producing ...
Shun-Kai Yang, Khatijah Yusoff, Mokrish Ajat, Wai-Sum Yap, Swee-Hua Erin Lim, Kok-Song Lai   +5 more
doaj   +1 more source