Results 91 to 100 of about 1,583,285 (309)

Current knowledge on Inquilinus limosus, a scarcely researched human pathogen

BMC Microbiology
Inquilinus limosus belongs to the class of the Alphaproteobacteria and was first described in 2002. So far, the species has mainly been isolated from respiratory specimens of patients with cystic fibrosis.
Oluwafemi M. Akinnurun, Thomas Riedel, Stephanie Müller, Boyke Bunk, Percy Schröttner   +4 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Rapid evolution of virulence and drug resistance in the emerging zoonotic pathogen Streptococcus suis [PDF]

, 2009
Background: Streptococcus suis is a zoonotic pathogen that infects pigs and can occasionally cause serious infections in humans. S. suis infections occur sporadically in human Europe and North America, but a recent major outbreak has been described in ...
Kehoe, M., Gottschalk, M, Mai, Nguyen Thi Hoang, Maskell, Duncan, Dowson, C G, Cherevach, I, Cambridge, Spratt, BG, Quail, M.A., Goodhead, Ian, Xu, J, Slater, J.D., Xu Jianguo, Maskell Duncan J., Nguyen, Tran Chinh, Inna Cherevach, Ian Goodhead, Sanders, M., Dowson, Christopher G., Whatmore Adrian M., Price, Claire, Price, C, Smith, Hilde E., Nicholas J Croucher, Dowson Christopher G., Schultz, C, Price Claire, Cherevach Inna, Newcastle, Neil Chanter, Mai, NT, Ward, P N, Rabbinowitsch Ester, Diep, To Song, Ngo, Thi Hoa, Goodhead, I., Holden, MT, Croucher, N., Thi Hoang Mai Nguyen, Claire Price, Iversen, P, Whatmore, A M, Jianguo, Xu, To, SD, Parkhill, Julian, Chanter, N, Croucher, NJ, Michael Kehoe, Chinh Nguyen Tran, Ye, Changyun, Tran Bich Chieu, Diep, T S, Holden, M T, Ngo Thi Hoa, Quail, MA, Nguyen, THM, Sanders Mandy, Iversen, P., Tran, BC, Sanders, M, Chinh, Nguyen Tran, Chieu, T B, Bentley, Stephen D., Mai, NTH, Nguyen, TC, Quail, M A, Changyun Ye, Ngo, T H, Holden, M.T.G., Croucher, N J, Whatmore, Adrian M., Hauser, H, Goodhead Ian, Leigh, J.A., Mungall, K, Holden, MTG, Cronin, Ann, Matthew T G Holden, Slater, Josh D., Maskell, Duncan J., Bentley, S., Sharp, S., Rabbinowitsch, E., Parkhill, J., Wageningen UR, The Netherlands, Sharp, S, Mungall, K., To Song Diep, Croucher Nicholas J., Hauser, Heidi, Xu, Jianguo, Iversen Pernille, Smith, H E, Universite de Montreal, Canada, Maskell, D.J., Michael A Quail, Stephen Bentley, Smith, HE, Croucher, Nicholas J., Nguyen Thi Hoang Mai, Karen Mungall, Barrell, B.G., Cronin Ann, Slater Josh D., Bentley, S, Smith, H.E., Schultsz, C, Nottingham, Parkhill Julian, Rabbinowitsch, Ester, Rabbinowitsch, E, Kehoe Michael, AHT, Copenhagen, Hoa Ngo, Thi, Marcelo Gottschalk, Ward, P.N., Leigh James A., Hauser, H., Schultsz, Constance, Hilde E Smith, Philip N Ward, Schultsz, C., Imperial College London, Gottschalk Marcelo, Chieu, Tran Bich, Chinh, NT, Adrian M Whatmore, Barrell, B G, Maskell, DJ, Barrell, Barclay G., Josh D Slater, Wellcome Trust, Slater, JD, To, Song Diep, Chieu Tran Bich, Changyun, Ye, Quail, Michael A., Thi Hoa Ngo, Sharp Sarah, Cherevach, I., Amsterdam, Spratt, B G, Gottschalk, Marcelo, Julian Parkhill, Spratt Brian G., Barrell, Bart G., Chanter, N., Mai, N T, Diep To Song, Schultsz Constance, Heidi Hauser, Maskell, D J, Ward Philip N., Dowson, CG, Slater, J D, Barrell Barclay G., Leigh, J A, Cherevach, Inna, Bentley, Stephen, Leigh, James A., Ngo, TH, Parkhill, J, Thi, HN, Constance Schultsz, Nguyen Tran Chinh, Holden, Matthew T. G., Iversen, Pernille, Barclay G Barrell, Chieu, TB, Whatmore, AM, Mungall Karen, Ward, Philip N., Cronin, A, Ester Rabbinowitsch, Barrell, BG, Quail Michael A., National Institute For Communicable Disease, Sanders, Mandy, Ye Changyun, Goodhead, I, Whatmore, A.M., Ye, C, Bentley Stephen, Brian G Spratt, Chanter Neil, Hauser Heidi, Warwick, Price, C., Cronin, A., Kehoe, M, Spratt, B.G., Holden Matthew T. G., Smith Hilde E., Duncan J Maskell, Chinh, N T, Sharp, Sarah, Chanter, Neil, Diep, TS, Hospital For Tropical Diseases, Vietnam, Pernille Iversen, Jianguo Xu, Leigh, JA, Nguyen, Thi Hoang Mai, Oxford, Gottschalk, M., Mandy Sanders, Spratt, Brian G., James A Leigh, Dowson, C.G., Ward, PN, Christopher G Dowson, Mungall, Karen, Ann Cronin, Kehoe, Michael, Sarah Sharp   +215 more
core   +1 more source

Apoptosis induced by bacterial pathogens

Microbial Pathogenesis, 1994
Programmed cell death is part of normal development and homeostasis. Apoptosis induced by bacteria appears to contribute to infectious diseases. Some bacteria produce toxins to kill host cells by the same pathway, apoptosis, through different mechanisms including pore formation, protein synthesis inhibition or adenylate cyclase activity.
Y, Chen, A, Zychlinsky
openaire   +2 more sources

A Bacterial Pathogen Flips the Riboswitch [PDF]

Cell Host & Microbe, 2009
Riboswitches are RNA structures traditionally viewed as acting in cis to regulate downstream gene expression in bacteria. In a recent issue of Cell, Loh and colleagues report on the ability of a riboswitch to act in trans to modulate the expression of a critical bacterial virulence regulator.
Xayarath, Bobbi, Freitag, Nancy E.
openaire   +2 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Duplex droplet digital PCR detection of Streptococcus uberis and Streptococcus dysgalactiae, major etiological agents of bovine mastitis

Frontiers in Animal Science
Bovine mastitis is one of the most important diseases affecting dairy cattle worldwide, resulting in significant economic losses due to high costs mainly associated with decreased production, antimicrobial treatment, and early culling of animals.
Leticia Diana, German Traglia, Virginia Diana, Luis Calvinho, Jimena Laporta, Andrés Iriarte, Rodrigo Puentes   +6 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Intestinal inflammation responds to microbial tissue load independent of pathogen/non-pathogen discrimination [PDF]

, 2012
The intestinal immune system mounts inflammatory responses to pathogens but tolerates harmless commensal microbiota. Various mechanisms for pathogen/non-pathogen discrimination have been proposed but their general relevance for inflammation control is ...
Dirk Bumann (126124), Dirk Bumann, Yvonne Willer (126110), Willer, Yvonne, Willer Yvonne, Müller, Beatrice, Bumann, D., Yvonne Willer, Willer, Y., Beatrice Müller, Müller Beatrice, Müller, B., Bumann, Dirk, Bumann Dirk, Beatrice Müller (166158)   +14 more
core   +2 more sources

Molybdenum Enzymes and How They Support Virulence in Pathogenic Bacteria

Frontiers in Microbiology, 2020
Mononuclear molybdoenzymes are highly versatile catalysts that occur in organisms in all domains of life, where they mediate essential cellular functions such as energy generation and detoxification reactions.
Qifeng Zhong, Bostjan Kobe, Bostjan Kobe, Ulrike Kappler   +3 more
doaj   +1 more source