Results 71 to 80 of about 1,583,285 (309)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Whole genome investigation of a divergent clade of the pathogen Streptococcus suis [PDF]

, 2015
This work was supported by a Longer and Larger (LoLa) grant from the Biotechnology and Biological Sciences Research Council (grant numbers BB/G020744/1, BB/G019177/1, BB/G019274/1, and BB/G003203/1), the UK Department for Environment, Food and Rural ...
Langford, P.R., Paul eLangford, Tucker, AW, Weinert, LA, Alexander W. Tucker, Baig, A., Peters, S.E., Rycroft, A.N., Tucker, A.W., Holden, Matthew T G, Wang, J., Howell, K.J., Peters, SE, Parkhill, J, Consortium, B., Wren, B.W., Tucker, Alexander W, Matthew T.G. Holden, Peters, S E, Langford, PR, Julian eParkhill, Roy R Chaudhuri, Sarah E Peters, Lucy A. Weinert, Andrew eRycroft, Wren, BW, Baig, A, Holden, M T G, Wren, B W, Jinhong eWang, Paul R. Langford, Alexander W Tucker, Wang, Jinhong, Maskell, DJ, Langford, Paul R, Holden, M.T.G., Abiyad Baig, Abiyad eBaig, Brendan W Wren, Holden, MTG, Maskell, Duncan J, Chaudhuri, RR, Rycroft, Andrew N, Rycroft, AN, Kate J. Howell, Tucker, A W, Weinert, Lucy A, Wren, Brendan W, Duncan J Maskell, Andrew N. Rycroft, BRaDP1T Consortium, Kate J Howell, Chaudhuri, R R, Peters, Sarah E, Holden, Matthew TG, Wang, J, Howell, K J, Duncan J. Maskell, Parkhill, J., Chaudhuri, Roy R, Roy R. Chaudhuri, Brendan W. Wren, Weinert, L.A., Baig, Abiyad, Rycroft, A N, Lucy A Weinert, Julian Parkhill, Matthew T. G. Holden, Maskell, D.J., Howell, Kate J, Parkhill, Julian, Maskell, D J, Sarah E. Peters, Weinert, L A, Howell, KJ, Langford, P R, Jinhong Wang, Chaudhuri, R.R.   +77 more
core   +2 more sources

Special Features of Bat Microbiota Differ From Those of Terrestrial Mammals

Frontiers in Microbiology, 2020
Bats (order Chiroptera) are one of the most diverse and widely distributed group of mammals with a close relationship to humans. Over the past few decades, a number of studies have been performed on bat viruses; in contrast, bacterial pathogens carried ...
Dong-Lei Sun, Yi-Zhou Gao, Yi-Zhou Gao, Xing-Yi Ge, Xing-Yi Ge, Zheng-Li Shi, Ning-Yi Zhou, Ning-Yi Zhou   +7 more
doaj   +1 more source

Prevalence and antimicrobial resistance profile of bacterial pathogens isolated from poultry in Jiangxi Province, China from 2020 to 2022

Poultry Science, 2023
: Poultry is one of the most commonly farmed species and the most widespread meat industries. However, numerous poultry flocks have been long threatened by pathogenic bacterial infections, especially antimicrobial resistant pathogens. Here the prevalence
Mei-Fang Tan, Hai-Qin Li, Qun Yang, Fan-Fan Zhang, Jia Tan, Yan-Bing Zeng, Qi-Peng Wei, Jiang-Nan Huang, Cheng-Cheng Wu, Na Li, Zhao-Feng Kang   +10 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Identification of the cir1 disease resistance gene in Arabidopsis thaliana [PDF]

, 2012
Includes bibliographical references.Plants rely on an elaborate multi-layered defence system to perceive and effectively respond to disease causing pathogens.
Diener, Anastashia
core   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Mitigation and current management attempts to limit pathogen survival and movement within farmed grassland. [PDF]

, 2007
To successfully curb microbial contamination of surface waters we need to understand, and holistically evaluate, the range of mitigation strategies that have been designed to protect watercourses from non-point agricultural sources, so as to use them to ...
Oliver, David M., Oliver, D. M., Heathwaite, A. L., David R. Chadwick, David M. Oliver, Chadwick, David R., Chadwick, D. R., Chris J. Hodgson, A. Louise Heathwaite, Hodgson, C. J., Hodgson, Chris J.   +10 more
core   +1 more source

House Flies Are Underappreciated Yet Important Reservoirs and Vectors of Microbial Threats to Animal and Human Health

Microorganisms, 2023
House flies are well recognized as filth-associated organisms and public nuisances. House flies create sanitation issues when they bridge the gap between microbe-rich breeding environments and animal/human habitations.
Dana Nayduch, Saraswoti Neupane, Victoria Pickens, Tanya Purvis, Cassandra Olds   +4 more
doaj   +1 more source