Results 51 to 60 of about 1,336,409 (334)
PLoS Biology, 2023 Animals use a variety of cell-autonomous innate immune proteins to detect viral infections and prevent replication. Recent studies have discovered that a subset of mammalian antiviral proteins have homology to antiphage defense proteins in bacteria ...
Edward M Culbertson, Tera C Levin
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Structure and sequence analyses of Bacteroides proteins BVU_4064 and BF1687 reveal presence of two novel predominantly-beta domains, predicted to be involved in lipid and cell surface interactions. [PDF]
, 2015 BackgroundN-terminal domains of BVU_4064 and BF1687 proteins from Bacteroides vulgatus and Bacteroides fragilis respectively are members of the Pfam family PF12985 (DUF3869).
Aravind, L +5 more
core +2 more sources
Toxinome—the bacterial protein toxin database
mBio, 2023 ABSTRACT Protein toxins are key molecular weapons in biology that are used to attack neighboring cells. Bacteria use protein toxins to kill or inhibit the growth of prokaryotic and eukaryotic cells using various modes of action that target essential cellular components.
Aleks Danov +6 more
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Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
MicroorganismsMycobacterium tuberculosis (Mtb) is the causative agent of tuberculosis, the world’s deadliest infectious disease. Mtb uses a variety of mechanisms to evade the human host’s defenses and survive intracellularly.
Bonnie J. Cuthbert +6 more
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Intracellular proteins moonlighting as bacterial adhesion factors
AIMS Microbiology, 2018 Pathogenic and commensal, or probiotic, bacteria employ adhesins on the cell surface to attach to and interact with the host. Dozens of the adhesins that play key roles in binding to host cells or extracellular matrix were originally identified as ...
Constance Jeffery
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Adaptive response and enlargement of dynamic range [PDF]
, 2011 Many membrane channels and receptors exhibit adaptive, or desensitized, response to a strong sustained input stimulus, often supported by protein activity-dependent inactivation.
A. Csik\'asz-Nagy +27 more
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Translocation of bacterial proteins?an overview
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2004 Recent progress in the understanding of the nature of the extraordinary variety of protein translocation systems, mainly in Gram negative bacteria, is reviewed. This takes us from the insertion of proteins into the inner membrane via the sophisticated Sec apparatus, the lethal injection of Type III proteins into host cells and on to the beautiful ...
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FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Surface Inactivation of Bacterial Viruses and of Proteins
Substantia, 2023 The extraordinary paper of Mark H. Adams: Surface Inactivation of Bacterial Viruses and of Proteins appeared in a mainstream Journal of Physiology, in 1948. It was neglected and has been ever since.
Mark H. Adams, Barry W. Ninham
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