Results 61 to 70 of about 7,915,148 (365)

TagF-mediated repression of bacterial type VI secretion systems involves a direct interaction with the cytoplasmic protein Fha [PDF]

, 2018
The bacterial type VI secretion system (T6SS) delivers effectors into eukaryotic host cells or toxins into bacterial competitor for survival and fitness.
Filloux, A, Lai, E-M, Lin, J-S, Pissaridou, P, Tsai, M-D, Wu, H-H   +5 more
core   +1 more source

Infectious Keratitis: Secreted Bacterial Proteins That Mediate Corneal Damage

Journal of Ophthalmology, 2013
Ocular bacterial infections are universally treated with antibiotics, which can eliminate the organism but cannot reverse the damage caused by bacterial products already present. The three very common causes of bacterial keratitis—Pseudomonas aeruginosa,
M. Marquart, R. O'Callaghan
semanticscholar   +1 more source

A distinct sortase SrtB anchors and processes a streptococcal adhesin AbpA with a novel structural property. [PDF]

, 2016
Surface display of proteins by sortases in Gram-positive bacteria is crucial for bacterial fitness and virulence. We found a unique gene locus encoding an amylase-binding adhesin AbpA and a sortase B in oral streptococci.
Haase, EM, Liang, X, Liu, B, Matthews, S, Scannapieco, FA, Wu, H, Zhu, F   +6 more
core   +1 more source

Subversion of the Endocytic and Secretory Pathways by Bacterial Effector Proteins

Front. Cell Dev. Biol., 2018
Intracellular bacteria have developed numerous strategies to hijack host vesicular trafficking pathways to form their unique replicative niches. To promote intracellular replication, the bacteria must interact with host organelles and modulate host ...
Mary M. Weber, R. Faris
semanticscholar   +1 more source

Bacterial Signal Peptides- Navigating the Journey of Proteins

Frontiers in Physiology, 2022
In 1971, Blobel proposed the first statement of the Signal Hypothesis which suggested that proteins have amino-terminal sequences that dictate their export and localization in the cell.
Sharbani Kaushik, Haoze He, Ross E. Dalbey   +2 more
doaj   +1 more source

The Bacterial Photosynthetic Reaction Center as a Model for Membrane Proteins [PDF]

, 1989
Membrane proteins participate in many fundamental cellular processes. Until recently, an understanding of the function and properties of membrane proteins was hampered by an absence of structural information at the atomic level.
Allen, J. P., Feher, G., Komiya, H., Rees, D. C., Yeates, T. O.   +4 more
core   +1 more source

SEDS proteins are a widespread family of bacterial cell wall polymerases

Nature, 2016
Elongation of rod-shaped bacteria is mediated by a dynamic peptidoglycan-synthetizing machinery called the Rod complex. Here we report that, in Bacillus subtilis, this complex is functional in the absence of all known peptidoglycan polymerases.
A. Meeske, Eammon P. Riley, W. Robins, T. Uehara, John J. Mekelanos, D. Kahne, S. Walker, A. Kruse, T. Bernhardt, D. Rudner   +9 more
semanticscholar   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Structural Characterization of Mycobacterium tuberculosis Encapsulin in Complex with Dye-Decolorizing Peroxide

Microorganisms
Mycobacterium tuberculosis (Mtb) is the causative agent of tuberculosis, the world’s deadliest infectious disease. Mtb uses a variety of mechanisms to evade the human host’s defenses and survive intracellularly.
Bonnie J. Cuthbert, Xiaorui Chen, Kalistyn Burley, Gaëlle Batot, Heidi Contreras, Shandee Dixon, Celia W. Goulding   +6 more
doaj   +1 more source

Intracellular proteins moonlighting as bacterial adhesion factors

AIMS Microbiology, 2018
Pathogenic and commensal, or probiotic, bacteria employ adhesins on the cell surface to attach to and interact with the host. Dozens of the adhesins that play key roles in binding to host cells or extracellular matrix were originally identified as ...
Constance Jeffery
doaj   +1 more source