Results 71 to 80 of about 7,190,308 (348)

Proteinaceous determinants of surface colonization in bacteria: Bacterial adhesion and biofilm formation from a protein secretion perspective

Frontiers in Microbiology, 2013
Bacterial colonization of biotic or abiotic surfaces results from two quite distinct physiological processes, namely bacterial adhesion and biofilm formation. Broadly speaking, a biofilm is defined as the sessile development of microbial cells.
Caroline eCHAGNOT, Caroline eCHAGNOT, Mohamed Amine eZORGANI, Thierry eASTRUC, Mickael eDesvaux   +4 more
doaj   +1 more source

A Multi-Label Classifier for Predicting the Subcellular Localization of Gram-Negative Bacterial Proteins with Both Single and Multiple Sites

PLoS ONE, 2011
Prediction of protein subcellular localization is a challenging problem, particularly when the system concerned contains both singleplex and multiplex proteins. In this paper, by introducing the “multi-label scale” and hybridizing the information of gene
Xuan Xiao, Zhi-cheng Wu, K. Chou
semanticscholar   +1 more source

Are There Bacterial-Protein Hybrids?

Experimental Biology and Medicine, 1929
Fourth generation of subcultures of B. typhosus, S. viridans, and certain other microorganisms grown in 10% horse serum (Ringer's solution) are agglutinated in dilutions of 1:20 to 1:160 by antihorse rabbit precipitin, controls cultures (nutrient broth) showing no agglutination.With eighth to twelfth generation subcultures of the same microorganisms ...
openaire   +2 more sources

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

Modulation of host microtubule dynamics by pathogenic bacteria

Biomolecular Concepts, 2012
The eukaryotic cytoskeleton is a vulnerable target of many microbial pathogens during the course of infection. Rearrangements of host cytoskeleton benefit microbes in various stages of their infection cycle such as invasion, motility, and persistence ...
Radhakrishnan Girish K., Splitter Gary A.   +1 more
doaj   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Understanding the Molecular Interactions Between Influenza A Virus and Streptococcus Proteins in Co-Infection: A Scoping Review

Pathogens
Influenza A virus infections are known to predispose infected individuals to bacterial infections of the respiratory tract that result in co-infection with severe disease outcomes.
Askar K. Alshammari, Meshach Maina, Adam M. Blanchard, Janet M. Daly, Stephen P. Dunham   +4 more
doaj   +1 more source

Genetic Reporter System for Positioning of Proteins at the Bacterial Pole

mBio, 2012
Spatial organization within bacteria is fundamental to many cellular processes, although the basic mechanisms underlying localization of proteins to specific sites within bacteria are poorly understood.
Kathryn R. Fixen, Anuradha Janakiraman, Sean Garrity, Daniel J. Slade, Andrew N. Gray, Nilay Karahan, Ann Hochschild, Marcia B. Goldberg   +7 more
doaj   +1 more source

Interactions of Bacterial Proteins with Host Eukaryotic Ubiquitin Pathways

Front. Microbio., 2011
Ubiquitination is a post-translational modification in which one or more 76 amino acid polypeptide ubiquitin molecules are covalently linked to the lysine residues of target proteins.
C. Perrett, D. Y. Lin, Daoguo Zhou
semanticscholar   +1 more source

Mycobacterium tuberculosis sulfurtransferase SseA is activated by its neighboring gene product Rv3284

FEBS Letters, EarlyView.
Tuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Giulia Di Napoli, Alex Fissore, Edoardo Salladini, Eleonora Raccuia, Simonetta Oliaro‐Bosso, Alessia Ruggiero, Rita Berisio, Milagros Medina, Adrian Velazquez‐Campoy, Salvatore Adinolfi, Mauro Marengo   +10 more
wiley   +1 more source