Results 121 to 130 of about 194,060 (257)

Targeted intracellular delivery of Cas13 and Cas9 nucleases using bacterial toxin-based platforms. [PDF]

Cell Rep, 2022
Tian S, Liu Y, Liu Y, Appleton E, Wang H, Church GM, Dong M.   +6 more
europepmc   +1 more source

Mr BMT Achieves Systemic Macrophage Replacement With Preservation of Tissue Homeostasis

Advanced Science, EarlyView.
Microglia replacement by bone marrow transplantation (Mr BMT) enables systemic replacement of tissue‐resident macrophages. Despite persistent macrophage and tissue remodeling across multiple organs, core biological functions and innate immune responses remain preserved, supporting long‐term maintenance of organismal homeostasis and the therapeutic ...
Yufei Xu, Miaozhan Zou, Yunshang Bai, Yang He, Zhihao Jin, Baozhi Yang, Jinjin Du, Pei Ouyang, Yuanyuan Cai, Yuheng Zhang, Bingying Du, Chengcheng Ge, Jian‐an Gong, Xiaoyu Li, Yuanyi Zheng, Jing Ding, Bo Peng, Yanxia Rao   +17 more
wiley   +1 more source

An RNA structural switch controlling bacterial toxin translation. [PDF]

Nucleic Acids Res
Eleftheraki A, Escalera-Maurer A, Hien EDM, Virciglio A, Conangle M, Tourasse NJ, Le Rhun A, Holmqvist E.   +7 more
europepmc   +1 more source

Strategies to Investigate Membrane Damage, Nucleoid Condensation, and RNase Activity of Bacterial Toxin-Antitoxin Systems. [PDF]

Methods Protoc, 2021
Maggi S, Ferrari A, Yabre K, Bonini AA, Rivetti C, Folli C.   +5 more
europepmc   +1 more source

A Review on Catalytic Nanostructured Electrodes for Wearable and Implantable Abiotic Glucose Fuel Cells

Advanced Science, EarlyView.
This review identifies current and future directions in abiotic nanostructured catalysts to develop reliable and sustainable glucose fuel cells to power the next generation of bioelectronic devices. ABSTRACT The global rise in incidence of chronic diseases has led to the demand for innovative solutions that help patients manage their conditions with ...
Asghar Niyazi, Hannah S. Leese, Benjamin Metcalfe, Mirella Di Lorenzo   +3 more
wiley   +1 more source

A pro-carcinogenic bacterial toxin binds claudin-4 to cleave E-cadherin. [PDF]

Nature
White MT, Wang K, Zhang H, Eckhard U, Hullahalli K, Chen J, Wu S, Geis AL, Zhang J, Queen J, Gomis-Ruth FX, Waldor MK, Dong M, Sears CL.   +13 more
europepmc   +1 more source

Luteolin Inhibits the Biofilm Formation and Cytotoxicity of Methicillin-Resistant Staphylococcus aureus via Decreasing Bacterial Toxin Synthesis. [PDF]

Evid Based Complement Alternat Med, 2022
Sun Y, Sun F, Feng W, Wang Q, Liu F, Xia P, Qiu X.   +6 more
europepmc   +1 more source

β‐Elemene Rescues Radiation‐Induced Enteritis by Orchestrating a Host‐Microbiome Circuit That Fuels Epigenetic DNA Repair

Advanced Science, EarlyView.
This study elucidates that β‐elemene promotes cellular uptake of L. gasseri‐derived lactate by enhancing the membrane translocation of MCT1 in a CD147‐dependent manner. Intracellular lactate, through the lactylation of RBBP4 at the K26 site, recruits EP300 to the promoter regions of downstream genes (POLD1/POLD3), catalyzing H3K27ac modification.
Jiancheng He, Jiapeng Bao, Shukang Deng, Weijie Zang, Haoming Yan, Zihao Zhao, Guangze Zhang, Ruiqing Liu, Junjie Chen, Yilin Hu, Wanjiang Xue   +10 more
wiley   +1 more source

Bacterial Toxin Exploits Host Membrane Phospholipid as a Receptor for Binding, Entry, and Cytopathogenicity. [PDF]

Mol Microbiol
Kirkpatrick AM, Kannan TR.
europepmc   +1 more source

Templated folding of the RTX domain of the bacterial toxin adenylate cyclase revealed by single molecule force spectroscopy. [PDF]

Nat Commun, 2022
Wang H, Chen G, Li H.
europepmc   +1 more source