Results 181 to 190 of about 308,540 (300)

A bacterial toxin-antitoxin system involved in an unusual response to genotoxic stress. [PDF]

EMBO Rep
Lin JD, Nicholson B, Ensminger AW.
europepmc   +1 more source

Interactions of Bacterial Toxin CNF1 and Host JAK1/2 Driven by Liquid-Liquid Phase Separation Enhance Macrophage Polarization. [PDF]

mBio, 2022
Sun X, Yang J, Deng X, Wei Y, Wang C, Guo Y, Yang H, Yang L, Miao C, Lv J, Xiao Y, Zhang H, Yao Z, Wang Q.   +13 more
europepmc   +1 more source

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang, Lihuan Shang, Xiaochun Chen, Xiangzhan Kong, Xiaojuan Wang, Linjia Jiang, Huiying Zhao, Yafeng Zhu, Cheng Huang, Shiyi Deng, Rui Zhang, Minghui Wang, Haoming Lin, Ping‐Pui Wong   +13 more
wiley   +1 more source

A bacterial toxin-antitoxin system as a native defence element against RNA phages. [PDF]

Biol Lett
Nikolic N, Pleška M, Bergmiller T, Guet CC.   +3 more
europepmc   +1 more source

Fructose-coated Ångstrom silver prevents sepsis by killing bacteria and attenuating bacterial toxin-induced injuries. [PDF]

Theranostics, 2021
Yin H, Zhou M, Chen X, Wan TF, Jin L, Rao SS, Tan YJ, Duan R, Zhang Y, Wang ZX, Wang YY, He ZH, Luo MJ, Hu XK, Wang Y, Situ WY, Tang SY, Liu WE, Chen CY, Xie H.   +19 more
europepmc   +1 more source

Culture of rectal swab specimens for enteric bacterial pathogens decreases time to test result while preserving assay sensitivity compared to bulk fecal specimens [PDF]

, 2019
Anderson, Neil W, Burnham, Carey-Ann D, Jean, Sophonie, Yarbrough, Melanie L   +3 more
core   +1 more source

Detection of Protein–Protein Interactions in Escherichia coli With Single Molecule Sensitivity

Advanced Science, EarlyView.
This article describes a regulatory circuit in Escherichia coli able to detect protein–protein interactions with exquisite sensitivity. The interaction between two hybrid proteins fused to Bordetella pertussis adenylate cyclase and its activator calmodulin triggers a potent cyclic AMP signaling cascade.
Marilyne Davi, Daniel Ladant
wiley   +1 more source

Messenger RNA delivery to mitoribosomes - hints from a bacterial toxin. [PDF]

FEBS J, 2021
Bruni F, Proctor-Kent Y, Lightowlers RN, Chrzanowska-Lightowlers ZM.   +3 more
europepmc   +1 more source

A Biomarker‐Driven Ovary–Endometrium Organ‐on‐a‐Chip Mimicking 3D Multicellular Complexity and Menstrual Cyclicity for Predicting Reproductive Toxicity

Advanced Science, EarlyView.
We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.
Soo‐Rim Kim, Eun‐kyung Min, Choon‐Mi Lee, Chan Hum Park, Byung‐Chul Oh, YunJae Jung, In‐Sun Hong   +6 more
wiley   +1 more source

Structural basis for sequence context-independent single-stranded DNA cytosine deamination by the bacterial toxin SsdA. [PDF]

Nat Commun
Yin L, Chen Y, Shi K, Barreto Duran E, Harris RS, Aihara H.   +5 more
europepmc   +1 more source