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Bacterial toxin vaccines

Vaccine, 1985
A rebirth of interest and activity in vaccine development has occurred in recent years which is probably due to the persistence of threat to health by infectious diseases, as well as technological advances which have made possible new approaches to solve old problems.
F, Dorner, J L, McDonel
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Targeting Bacterial Toxins

Angewandte Chemie International Edition, 2012
AbstractProtein toxins constitute the main virulence factors of several species of bacteria and have proven to be attractive targets for drug development. Lead candidates that target bacterial toxins range from small molecules to polymeric binders, and act at each of the multiple steps in the process of toxin‐mediated pathogenicity.
Mattias E, Ivarsson   +2 more
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Bacterial Toxins and Diarrhoea

Clinics in Gastroenterology, 1986
Bacteria and their toxins are responsible for an enormous burden of diarrhoeal disease. Knowledge about the toxins and their mechanisms of action is limited. Thus, although considerable information is available about the mechanism of action of cholera toxin and a small number of heat-stable enterotoxins, information on the role and action of many ...
K J, Moriarty, L A, Turnberg
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The bacterial toxin toolkit

Nature Reviews Molecular Cell Biology, 2001
Pathogenic bacteria and higher eukaryotes have spent a long time together, leading to a precise understanding of one another's way of functioning. Through rapid evolution, bacteria have engineered increasingly sophisticated weapons to hit exactly where it hurts, interfering with fundamental host functions.
G, Schiavo, F G, van der Goot
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Bacterial Insecticidal Toxins

Critical Reviews in Microbiology, 2004
Over the years it has been important for humans to control the populations of harmful insects and insecticides have been used for this purpose in agricultural and horticultural sectors. Synthetic insecticides, owing to their various side effects, have been widely replaced by biological insecticides. In this review we attempt to describe three bacterial
Abanti, Chattopadhyay   +2 more
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Bacterial Toxins as Immunomodulators

2009
Bacterial toxins are the causative agent at pathology in a variety of diseases. Although not always the primary target of these toxins, many have been shown to have potent immunomodulatory effects, for example, inducing immune responses to co-administered antigens and suppressing activation of immune cells.
David S, Donaldson, Neil A, Williams
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Preformed Bacterial Toxins

Clinics in Laboratory Medicine, 1999
Food poisoning syndromes caused by four different bacteria are described. For all types, food kept at a permissive temperature allows growth of the vegetative forms of the bacteria and production of a toxin or toxins. The key features of these syndromes, as well as possible new trends of concern, are summarized in Table 1.
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Genetic Detoxification of Bacterial Toxins

2003
Several pathogens, such as Corynebacterium diphtheriae, Clostridium tetani, Bordetella pertussis, Vibrio cholerae, enterotoxigenic Escherichia co1i (1), and even some emerging pathogens, such as Helicobacter pylori (2), produce potent toxins that are responsible for the pathology caused by the bacterium.
Pizza M.   +3 more
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Bacterial Toxins

The Hospital
In the globalizing world, food safety and food-borne pathogenic microorganisms are among the important public health problems. There are more than 250 known foodborne diseases and many different types of viruses, bacteria, parasites, toxins, metals and prions that cause these diseases.
Reyhan Gul Guven, Kemal Guven
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Bacterial Toxins

2020
Background/Aim: Poisonous molecules produced by bacteria inside or outside the organisms are generally called "toxins". The ability of bacteria to synthesize toxins is called "toxicity". Toxigenicity is an important factor that increases the virulence of bacteria.
YÜKSEL DOLGUN, Hafize Tuğba   +3 more
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