Sequence Variability of P2-Like Prophage Genomes Carrying the Cytolethal Distending Toxin V Operon in Escherichia coli O157 [PDF]
, 2013 Cytolethal distending toxins (CDT) are potent cytotoxins of several Gram-negative pathogenic bacteria, including Escherichia coli, in which five types (CDT-I to CDT-V) have been identified so far.
Dobrindt, Ulrich +4 more
core +1 more source
mBio, 2018 Toxin neutralizing antibodies represent the major mode of protective immunity against a number of toxin-mediated bacterial diseases, including anthrax; however, the cellular mechanisms that lead to optimal neutralizing antibody responses remain ill ...
Anita Verma +5 more
doaj +1 more source
Mechanisms for Differential Protein Production in Toxin–Antitoxin Systems
Toxins, 2017 Toxin–antitoxin (TA) systems are key regulators of bacterial persistence, a multidrug-tolerant state found in bacterial species that is a major contributing factor to the growing human health crisis of antibiotic resistance. Type II TA systems consist of
Heather S. Deter +3 more
doaj +1 more source
Frontiers in Microbiology, 2022 Shiga toxin-producing Escherichia coli (STEC) are food-borne pathogens that can cause severe symptoms for humans. Raw milk products are often incriminated as vehicule for human STEC infection.
Arthur Bagel +6 more
doaj +1 more source
Secondary bacterial infections of buruli ulcer lesions before and after chemotherapy with streptomycin and rifampicin [PDF]
, 2013 Buruli ulcer (BU), caused by Mycobacterium ulcerans is a chronic necrotizing skin disease. It usually starts with a subcutaneous nodule or plaque containing large clusters of extracellular acid-fast bacilli.
Kwabena Quenin-Fosu +48 more
core +2 more sources
A novel type I toxin-antitoxin system modulates persister cell formation in Staphylococcus aureus
International Journal of Medical Microbiology, 2020 A plethora of toxin-antitoxin systems exist in bacteria and has multilateral roles in bacterial pathogenesis and virulence. Toxin-antitoxin systems have been involved in persister cell formation in Escherichia coli and Mycobacterium but have not been ...
Gul Habib, Jiade Zhu, Baolin Sun
doaj +1 more source
Clostridium perfringensepsilon toxin H149A mutant as a platform for receptor binding studies [PDF]
, 2013 Clostridium perfringens epsilon toxin (Etx) is a pore-forming toxin responsible for a severe and rapidly fatal enterotoxemia of ruminants. The toxin is classified as a category B bioterrorism agent by the U.S.
Titball, R.W. +21 more
core +1 more source
The effect of Staphylococcus aureus carriage in late pregnancy on antibody levels to staphylococcal toxins in cord blood and breast milk. [PDF]
, 2008 We investigated the effect of carriage of Staphylococcus aureus in the later stages of pregnancy on levels of antibody specific to the S. aureus toxins, staphylococcal enterotoxin B (SEB), staphylococcal enterotoxin C (SEC) and toxic shock syndrome toxin-
Morris, James A. +3 more
core +4 more sources
BTXpred: Prediction of Bacterial Toxins
In Silico Biology: Journal of Biological Systems Modeling and Multi-Scale Simulation, 2007 This paper describes a method developed for predicting bacterial toxins from their amino acid sequences. All the modules, developed in this study, were trained and tested on a non-redundant dataset of 150 bacterial toxins that included 77 exotoxins and 73 endotoxins. Firstly, support vector machines (SVM) based modules were developed for predicting the
Sudipto Saha, Gajendra P. S. Raghava
openaire +3 more sources
Comparative analysis of antimicrobial activities of valinomycin and cereulide, the Bacillus cereus emetic toxin [PDF]
, 2011 Cereulide and valinomycin are highly similar cyclic dodecadepsipeptides with potassium ionophoric properties. Cereulide, produced by members of the Bacillus cereus group, is known mostly as emetic toxin, and no ecological function has been assigned.
Marcel H. Tempelaars +5 more
core +1 more source