Impact of Bacterial Toxins in the Lungs [PDF]
Bacterial toxins play a key role in the pathogenesis of lung disease. Based on their structural and functional properties, they employ various strategies to modulate lung barrier function and to impair host defense in order to promote infection. Although
Rudolf Lucas+13 more
doaj +7 more sources
Bacterial Toxins for Cancer Therapy [PDF]
Several pathogenic bacteria secrete toxins to inhibit the immune system of the infected organism. Frequently, they catalyze a covalent modification of specific proteins. Thereby, they block production and/or secretion of antibodies or cytokines. Moreover,
Nour-Imene Zahaf, Gudula Schmidt
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Clostridial Neurotoxins: Structure, Function and Implications to Other Bacterial Toxins [PDF]
Gram-positive bacteria are ancient organisms. Many bacteria, including Gram-positive bacteria, produce toxins to manipulate the host, leading to various diseases. While the targets of Gram-positive bacterial toxins are diverse, many of those toxins use a
Shuowei Cai, Raj Kumar, Bal Ram Singh
doaj +3 more sources
Bacterial Toxins, Current Perspectives [PDF]
Toxins are the major pathogenicity factors produced by numerous bacteria involved in severe diseases in humans and animals. Certain pathogenic bacteria synthesize only one toxin which is responsible for all the symptoms and outcome of the disease.
Michel R. Popoff
doaj +5 more sources
Interactions between Autophagy and Bacterial Toxins: Targets for Therapy? [PDF]
Autophagy is a physiological process involved in defense mechanisms for clearing intracellular bacteria. The autophagic pathway is finely regulated and bacterial toxins interact with this process in a complex manner.
Jacques Mathieu
doaj +3 more sources
New Strategies for Biocontrol of Bacterial Toxins and Virulence: Focusing on Quorum-Sensing Interference and Biofilm Inhibition. [PDF]
The overuse of antibiotics and the emergence of multiple-antibiotic-resistant pathogens are becoming a serious threat to health security and the economy.
Zhang H, Zhang Z, Li J, Qin G.
europepmc +2 more sources
Evolution of insect innate immunity through domestication of bacterial toxins. [PDF]
Significance Several disease-causing bacteria produce toxins that damage host cells by triggering preprogrammed cell death. Two such bacterial toxins are called cytolethal distending toxin B and apoptosis-inducing protein of 56 kDa.
Verster KI+12 more
europepmc +2 more sources
Advances in the Study of Bacterial Toxins, Their Roles and Mechanisms in Pathogenesis. [PDF]
Pathogenic bacteria use various mechanisms to cause infections in the host. Bacterial pathogens express a wide range of molecules. Bacterial toxins have a poisonous substance created and secreted at the extracellular or intracellular level, making these ...
Ghazaei C.
europepmc +2 more sources
Bacterial Toxins Active against Mosquitoes: Mode of Action and Resistance. [PDF]
Larvicides based on the bacteria Bacillus thuringiensis svar. israelensis (Bti) and Lysinibacillus sphaericus are effective and environmentally safe compounds for the control of dipteran insects of medical importance.
Silva-Filha MHNL+7 more
europepmc +2 more sources
Use of Short-Chain Fatty Acids for the Recovery of the Intestinal Epithelial Barrier Affected by Bacterial Toxins. [PDF]
Short-chain fatty acids (SCFAs) are carboxylic acids produced as a result of gut microbial anaerobic fermentation. They activate signaling cascades, acting as ligands of G-protein-coupled receptors, such as GPR41, GPR43, and GPR109A, that can modulate ...
Pérez-Reytor D+3 more
europepmc +2 more sources