Results 1 to 10 of about 1,461,971 (329)
Impact of Bacterial Toxins in the Lungs [PDF]
Toxins, 2020 Bacterial toxins play a key role in the pathogenesis of lung disease. Based on their structural and functional properties, they employ various strategies to modulate lung barrier function and to impair host defense in order to promote infection. Although
Rudolf Lucas +13 more
doaj +7 more sources
Bacterial Toxins for Cancer Therapy [PDF]
Toxins, 2017 Several pathogenic bacteria secrete toxins to inhibit the immune system of the infected organism. Frequently, they catalyze a covalent modification of specific proteins. Thereby, they block production and/or secretion of antibodies or cytokines. Moreover,
Nour-Imene Zahaf, Gudula Schmidt
doaj +8 more sources
Clostridial Neurotoxins: Structure, Function and Implications to Other Bacterial Toxins [PDF]
Microorganisms, 2021 Gram-positive bacteria are ancient organisms. Many bacteria, including Gram-positive bacteria, produce toxins to manipulate the host, leading to various diseases. While the targets of Gram-positive bacterial toxins are diverse, many of those toxins use a
Shuowei Cai, Raj Kumar, Bal Ram Singh
doaj +3 more sources
Bacterial Toxins, Current Perspectives [PDF]
Toxins, 2020 Toxins are the major pathogenicity factors produced by numerous bacteria involved in severe diseases in humans and animals. Certain pathogenic bacteria synthesize only one toxin which is responsible for all the symptoms and outcome of the disease.
Michel R. Popoff
doaj +5 more sources
Special Issue: Gram-Positive Bacterial Toxins [PDF]
Microorganisms, 2023 The Gram stain classifies most bacteria into one of two groups, Gram-negative or Gram-positive, based on the composition of their cell walls [...]
Shashi Sharma +2 more
doaj +2 more sources
Bacterial toxins in musculoskeletal infections. [PDF]
J Orthop Res, 2021 Musculoskeletal infections (MSKIs) remain a major health burden in orthopaedics. Bacterial toxins are foundational to pathogenesis in MSKI, but poorly understood by the community of providers that care for patients with MSKI, inducing an international group of microbiologists, infectious diseases specialists, orthopaedic surgeons and biofilm scientists
Saeed K +17 more
europepmc +6 more sources
Autoproteolytic Activation of Bacterial Toxins [PDF]
Toxins, 2010 Protease domains within toxins typically act as the primary effector domain within target cells. By contrast, the primary function of the cysteine protease domain (CPD) in Multifunctional Autoprocessing RTX-like (MARTX) and Clostridium sp.
Aimee Shen
doaj +4 more sources
Some Examples of Bacterial Toxins as Tools [PDF]
ToxinsPathogenic bacteria produce diverse protein toxins to disturb the host’s defenses. This includes the opening of epithelial barriers to establish bacterial growth in deeper tissues of the host and to modulate immune cell functions.
Gudula Schmidt
doaj +2 more sources
The bacterial toxin toolkit [PDF]
Nature Reviews Molecular Cell Biology, 2001 Pathogenic bacteria and higher eukaryotes have spent a long time together, leading to a precise understanding of one another's way of functioning. Through rapid evolution, bacteria have engineered increasingly sophisticated weapons to hit exactly where it hurts, interfering with fundamental host functions.
Giampietro Schiavo +1 more
openalex +4 more sources
Bacterial Toxins: Friends or Foes?
Emerging Infectious Diseases, 1999 Many emerging and reemerging bacterial pathogens synthesize toxins that serve as primary virulence factors. We highlight seven bacterial toxins produced by well-established or newly emergent pathogenic microbes.
Clare K. Schmitt +2 more
doaj +3 more sources