Bacterial Toxins Are a Never-Ending Source of Surprises: From Natural Born Killers to Negotiators. [PDF]
Lopez Chiloeches M +2 more
europepmc +3 more sources
Regulatory Networks Controlling Neurotoxin Synthesis in Clostridium botulinum and Clostridium tetani
Clostridium botulinum and Clostridium tetani are Gram-positive, spore-forming, and anaerobic bacteria that produce the most potent neurotoxins, botulinum toxin (BoNT) and tetanus toxin (TeNT), responsible for flaccid and spastic paralysis, respectively ...
Michel R. Popoff, Holger Brüggemann
doaj +1 more source
Anaerobes and Toxins, a Tradition of the Institut Pasteur
Louis Pasteur, one of the eminent pioneers of microbiology, discovered life without oxygen and identified the first anaerobic pathogenic bacterium. Certain bacteria were found to be responsible for specific diseases.
Michel R. Popoff, Sandra Legout
doaj +1 more source
Clostridium tetani produces the tetanus toxin (TeNT), one of the most powerful bacterial toxins known to humankind and responsible for tetanus. The regulation of toxin expression is complex and involves the alternative sigma factor TetR as well as other ...
Holger Brüggemann +3 more
doaj +1 more source
No evidence for a culturable bacterial tetrodotoxin producer in Pleurobranchaea maculata (Gastropoda: Pleurobranchidae) and Stylochoplana sp. (Platyhelminthes: Polycladida) [PDF]
Tetrodotoxin (TTX) is a potent neurotoxin found in the tissues of many taxonomically diverse organisms. Its origin has been the topic of much debate, with suggestions including endogenous production, acquisition through diet, and symbiotic bacterial ...
Cary, S. Craig +3 more
core +6 more sources
Structural insights into Clostridium perfringens delta toxin pore formation [PDF]
Clostridium perfringens Delta toxin is one of the three hemolysin-like proteins produced by C. perfringens type C and possibly type B strains. One of the others, NetB, has been shown to be the major cause of Avian Nectrotic Enteritis, which following the
AGW Leslie +57 more
core +15 more sources
Reversible cross-tolerance to platelet-activating factor signaling by bacterial toxins
Bacterial toxins signaling through Toll-like receptors (TLRs) are implicated in the pathogenesis of many inflammatory diseases. Among the toxins, lipopolysaccharide (LPS) exerts its action via TLR-4 while lipoteichoic acid (LTA) and bacterial ...
Kandahalli Venkataranganayaka Abhilasha +5 more
doaj +1 more source
Bacteria-derived chimeric toxins as potential anticancer agents
Cancer is one of the major causes of death globally, requiring everlasting efforts to develop novel, specific, effective, and safe treatment strategies.
Saeed Khoshnood +7 more
doaj +1 more source
Glabralysins, potential New β-pore-forming toxin family members from the schistosomiasis vector snail biomphalaria glabrata [PDF]
Biomphalaria glabrata is a freshwater Planorbidae snail. In its environment, this mollusk faces numerous microorganisms or pathogens, and has developed sophisticated innate immune mechanisms to survive.
Crickmore, Neil +6 more
core +3 more sources

