Results 21 to 30 of about 1,461,971 (329)
Decoy exosomes provide protection against bacterial toxins. [PDF]
Nature, 2020 Keller MD +8 more
europepmc +2 more sources
Interferon-mediated reprogramming of membrane cholesterol to evade bacterial toxins. [PDF]
Nat Immunol, 2020 Plasma membranes of animal cells are enriched for cholesterol. Cholesterol-dependent cytolysins (CDCs) are pore-forming toxins secreted by bacteria that target membrane cholesterol for their effector function.
Zhou QD +19 more
europepmc +2 more sources
Regulatory Networks Controlling Neurotoxin Synthesis in Clostridium botulinum and Clostridium tetani
Toxins, 2022 Clostridium botulinum and Clostridium tetani are Gram-positive, spore-forming, and anaerobic bacteria that produce the most potent neurotoxins, botulinum toxin (BoNT) and tetanus toxin (TeNT), responsible for flaccid and spastic paralysis, respectively ...
Michel R. Popoff, Holger Brüggemann
doaj +1 more source
Anaerobes and Toxins, a Tradition of the Institut Pasteur
Toxins, 2023 Louis Pasteur, one of the eminent pioneers of microbiology, discovered life without oxygen and identified the first anaerobic pathogenic bacterium. Certain bacteria were found to be responsible for specific diseases.
Michel R. Popoff, Sandra Legout
doaj +1 more source
Scientific Reports, 2021 Clostridium tetani produces the tetanus toxin (TeNT), one of the most powerful bacterial toxins known to humankind and responsible for tetanus. The regulation of toxin expression is complex and involves the alternative sigma factor TetR as well as other ...
Holger Brüggemann +3 more
doaj +1 more source
Evolutionary Features in the Structure and Function of Bacterial Toxins. [PDF]
Toxins (Basel), 2019 Toxins can function both as a harmful and therapeutic molecule, depending on their concentrations. The diversity in their function allows us to ask some very pertinent questions related to their origin and roles: (a) What makes them such effective ...
Kumar R +5 more
europepmc +2 more sources
Microbiology, 2022 Pore-forming toxins (PFTs) are widely distributed in both Gram-negative and Gram-positive bacteria. PFTs can act as virulence factors that bacteria utilise in dissemination and host colonisation or, alternatively, they can be employed to compete with ...
Fatima R. Ulhuq, Giuseppina Mariano
semanticscholar +1 more source
Activation mechanisms of inflammasomes by bacterial toxins
Cellular Microbiology, 2021 Inflammasomes are cytosolic innate immune complexes, which assemble in mammalian cells in response to microbial components and endogenous danger signals. A major family of inflammasome activators is bacterial toxins. Inflammasome sensor proteins, such as
Weidong Jing +3 more
semanticscholar +1 more source
JAMA: The Journal of the American Medical Association, 1901 Our object in presenting this paper is merely to outline the theory of the nature and action of the bacterial toxins which we are endeavoring to demonstrate, and to describe our method of work and the results which we have reached through the experiments we have so far made, which are very incomplete and really only a beginning toward the thorough ...
Thomas B. Cooley, Victor C. Vaughan
openaire +2 more sources
Bacterial Type I Toxins: Folding and Membrane Interactions
Toxins, 2021 Bacterial type I toxin-antitoxin systems are two-component genetic modules that encode a stable toxic protein whose ectopic overexpression can lead to growth arrest or cell death, and an unstable RNA antitoxin that inhibits toxin translation during ...
S. Nonin-Lecomte +3 more
semanticscholar +1 more source