Results 11 to 20 of about 94,986 (281)
Bacterial Spores as Vaccine Vehicles [PDF]
Infection and Immunity, 2003 ABSTRACT For the first time, bacterial spores have been evaluated as vaccine vehicles. Bacillus subtilis spores displaying the tetanus toxin fragment C (TTFC) antigen were used for oral and intranasal immunization and were shown to generate mucosal and systemic responses in a murine model.
DUC L. H. +4 more
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Determination of Endotoxicity in Bacterial Vaccines [PDF]
Applied Microbiology, 1973 Endotoxicity of bacterial vaccines was quantitated in mice by using actinomycin D as potentiating agent. The results were compared with those obtained by the mouse weight gain test. The lethality of Escherichia coli lipopolysaccharide was increased 2,140 times when 12.5 μg of actinomycin D was used.
K. H. Wong +7 more
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Bacterial vaccines in poultry [PDF]
Bulletin of the National Research Centre, 2020 Background Poultry bacterial pathogens are mainly controlled by using high-cost sanitary measures and medical treatment. However, the drug-resistant strains of pathogens continuously emerge, and medical treatments are often ineffective.
Nagwa S. Rabie, Zeinab M. S. Amin Girh
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Bacterial Proteomics and Vaccine Development [PDF]
American Journal of PharmacoGenomics, 2002 Until recently, the development of vaccines for use in humans relied on the response to attenuated or whole-cell preparations, or empirically selected antigens. The post-genomic era holds the possibility of rational design of novel vaccines for important human pathogens.
Carol L. Nilsson
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Bacterial pathogen genomics and vaccines [PDF]
British Medical Bulletin, 2002 Infectious diseases remain a major cause of deaths and disabilities in the world, the majority of which are caused by bacteria. Although immunisation is the most cost effective and efficient means to control microbial diseases, vaccines are not yet available to prevent many major bacterial infections.
Rino Rappuoli, Richard Moxon
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Bacterial vaccines and antibiotic resistance
Upsala Journal of Medical Sciences, 2014 Spread of antibiotic resistance is mediated by clonal lineages of bacteria that besides being resistant also possess other properties promoting their success. Some vaccines already in use, such as the pneumococcal conjugate vaccines, have had an effect on these successful clones, but at the same time have allowed for the expansion and resistance ...
Birgitta Henriques-Normark +1 more
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npj Vaccines, 2021 The development and use of antibacterial glycoconjugate vaccines have significantly reduced the occurrence of potentially fatal childhood and adult diseases such as bacteremia, bacterial meningitis, and pneumonia.
Chakkumkal Anish +2 more
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Журнал инфектологии, 2023 Purpose: To study the reactogenicity, safety and immunogenicity of the Russian vaccine Flu-M in comparison with Vaxigrip vaccine for influenza prevention in children aged from 6 months to 9 years (phase III).Materials and Methods.
A. M. Korolyuk +8 more
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Clonal analysis of meningococci during a 26 year period prior to the introduction of meningococcal serogroup C vaccines [PDF]
, 2015 Meningococcal disease remains a public health burden in the UK and elsewhere. Invasive Neisseria meningitidis, isolated in Scotland between 1972 and 1998, were characterised retrospectively to examine the serogroup and clonal structure of the circulating
Clarke, Stuart C. +3 more
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Chikungunya vaccines: advances in the development and prospects for marketing approval
Биопрепараты: Профилактика, диагностика, лечение, 2023 Chikungunya fever is an acute infectious disease caused by the mosquito-borne Chikungunya virus (CHIKV). In the last decades, cases of the disease have been reported in more than 100 countries; therefore, CHIKV presents a global public health problem ...
E. V. Otrasheuskaja +3 more
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