Results 11 to 20 of about 112,154 (311)
npj Vaccines, 2021 The development and use of antibacterial glycoconjugate vaccines have significantly reduced the occurrence of potentially fatal childhood and adult diseases such as bacteremia, bacterial meningitis, and pneumonia.
Chakkumkal Anish +2 more
doaj +1 more source
Development and validation of a targeted LC-MS/MS quantitation method to monitor cell culture expression of tetanus neurotoxin during vaccine production [PDF]
Talanta vol. 236 (2022): 122883, 2022 The tetanus neurotoxin (TeNT) is one of the most toxic proteins known to man, which prior to the use of the vaccine against the TeNT producing bacteria Clostridium tetani, resulted in a 20 % mortality rate upon infection. The clinical detrimental effects of tetanus have decreased immensely since the introduction of global vaccination programs, which ...
arxiv +1 more source
Chikungunya vaccines: advances in the development and prospects for marketing approval
Биопрепараты: Профилактика, диагностика, лечение, 2023 Chikungunya fever is an acute infectious disease caused by the mosquito-borne Chikungunya virus (CHIKV). In the last decades, cases of the disease have been reported in more than 100 countries; therefore, CHIKV presents a global public health problem ...
E. V. Otrasheuskaja +3 more
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Vaccines against bacterial meningitis [PDF]
British Medical Bulletin, 2004 Meningitis remains an important cause of morbidity and mortality among children >5 years of age and is especially prevalent in developing countries. Effective routine immunization against Hib, pneumococcus and serogroupC meningococcus has had a significant impact on both invasive disease and carriage caused by these encapsulated bacteria.
Segal, S, Pollard, A
openaire +4 more sources
Viruses, 2023 Phage endolysin-specific binding characteristics and killing activity support their potential use in biotechnological applications, including potency and purity testing of live biotherapeutic products (LBPs).
Robert J. Dorosky +5 more
doaj +1 more source
Co-evolution of Vaccination Behavior and Perceived Vaccination Risk can lead to a Stag-Hunt like Game [PDF]
, 2022 Voluntary vaccination is effective to prevent infectious diseases from spreading. Both vaccination behavior and cognition of the vaccination risk play important roles in individual vaccination decision making. However, it is not clear how the co-evolution of the two shapes the population-wide vaccination behavior.
arxiv +1 more source
Bacteria hinder large-scale transport and enhance small-scale mixing in time-periodic flows [PDF]
, 2021 Understanding mixing and transport of passive scalars in active fluids is important to many natural (e.g. algal blooms) and industrial (e.g. biofuel, vaccine production) processes. Here, we study the mixing of a passive scalar (dye) in dilute suspensions of swimming Escherichia coli in experiments using a two-dimensional (2D) time-periodic flow and in ...
arxiv +1 more source
High dissolved oxygen tension triggers outer membrane vesicle formation by Neisseria meningitidis
Microbial Cell Factories, 2018 Background Outer membrane vesicles (OMVs) are nanoparticles released by Gram-negative bacteria and can be used as vaccines. Often, detergents are used to promote release of OMVs and to remove the toxic lipopolysaccharides.
Matthias J. H. Gerritzen +6 more
doaj +1 more source
Биопрепараты: Профилактика, диагностика, лечение, 2022 Diseases caused by Streptococcus pneumoniae, as well as antibiotic resistance of its serotypes, are the leading cause of death amongst children worldwide.
V. P. Trukhin +5 more
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Accurate Measures of Vaccination and Concerns of Vaccine Holdouts from Web Search Logs [PDF]
, 2023 To design effective vaccine policies, policymakers need detailed data about who has been vaccinated, who is holding out, and why. However, existing data in the US are insufficient: reported vaccination rates are often delayed or missing, and surveys of vaccine hesitancy are limited by high-level questions and self-report biases. Here, we show how large-
arxiv +1 more source