Results 81 to 90 of about 213,855 (329)

Invasive bacterial infections in Gambians with sickle cell anaemia in an era of widespread Pneumococcal and Haemophilus influenzae type B vaccination [PDF]

, 2016
Background: There is relatively little data on the aetiology of bacterial infections in patients with sickle cell anaemia (SCA) in West Africa, and no data from countries that have implemented conjugate vaccines against both Streptococcus pneumoniae and ...
Anderson, ST, Bah, G, Cunnington, A, Darboe, S, Lawal, B, Soothill, G   +5 more
core   +1 more source

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

Advanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

Stability Study of Iriba Brucellosis Full-dose and Reduced-dose Vaccine Produced by Razi Institute in Iran

Archives of Razi Institute, 2015
Stability study of biological products plays an important role for determination of product changes in maintenance period and ensuring of safety and efficacy of vaccines.
Hasannia, E., Soleimani, S., Alamian, S., Behrozikhah, A., Emadi, A., Dostdari, S.   +5 more
doaj  

Polyhydroxyalkanoate beads as a particulate vaccine against Streptococcus pneumoniae and Neisseria meningitidis : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Microbiology at Massey University, Manawatu, New Zealand [PDF]

, 2017
Listed in 2018 Dean's List of Exceptional ThesesStreptococcus pneumoniae and Neisseria meningitidis are the major causes of pneumonia and meningitis, respectively, worldwide.
González Miró, Majela
core  

Invasive meningococcal disease in the Veneto region of Italy: A capture-recapture analysis for assessing the effectiveness of an integrated surveillance system [PDF]

, 2017
open8noBACKGROUND: Epidemiology of Neisseria meningitidis has been changing since the introduction of universal vaccination programmes against meningococcal serogroup C (MenC) and meningococcal serogroup B (MenB) has now become dominant.
Baldo, Vincenzo, Baldovin, Tatjana, Bertoncello, Chiara, Cocchio, Silvia, Furlan, Patrizia, Lazzari, Roberta, Russo, Francesca, Saia, Mario   +7 more
core   +1 more source

Implantable Microarray Patch: Engineering at the Nano and Macro Scale for Sustained Therapeutic Release via Synthetic Biodegradable Polymers

Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao, Akmal Hidayat Bin Sabri, Mary B. McGuckin, Linlin Li, Zihao Wang, Eneko Larrañeta, Ryan F. Donnelly   +6 more
wiley   +1 more source

Putative correlates of protection against shigellosis assessing immunomarkers across responses to S. sonnei investigational vaccine

npj Vaccines
Shigella spp. are a leading bacterial cause of diarrhea. No widely licensed vaccines are available and there is no generally accepted correlate of protection. We tested a S.
Valentino Conti, Omar Rossi, Kristen A. Clarkson, Francesca Mancini, Usman N. Nakakana, Eleanna Sarakinou, Andrea Callegaro, Pietro Ferruzzi, Alessandra Acquaviva, Ashwani Kumar Arora, Elisa Marchetti, Francesca Necchi, Robert W. Frenck, Laura B. Martin, Robert W. Kaminski, Audino Podda, Francesca Micoli   +16 more
doaj   +1 more source

Hydrogel Confinement Strategies for 3D Cell Culture in Microfluidic Systems

Advanced Materials Technologies, EarlyView.
Hydrogel confinement structures are key to organizing 3D cell cultures in microfluidic devices. This review classifies five structural strategies (micropillar, phaseguide, porous membrane, stepped‐height, and support‐free) and examines their trade‐offs alongside fabrication methods.
Soohyun Kim, Min Seok Lee, Sung Kyun Lee
wiley   +1 more source

Phage-specific immunity impairs efficacy of bacteriophage targeting Vancomycin Resistant Enterococcus in a murine model

Nature Communications
Bacteriophage therapy is a promising approach to address antimicrobial infections though questions remain regarding the impact of the immune response on clinical effectiveness.
Julia D. Berkson, Claire E. Wate, Garrison B. Allen, Alyxandria M. Schubert, Kristin E. Dunbar, Michael P. Coryell, Rosa L. Sava, Yamei Gao, Jessica L. Hastie, Emily M. Smith, Charlotte R. Kenneally, Sally K. Zimmermann, Paul E. Carlson   +12 more
doaj   +1 more source

Multitasking Smart Intestinal Capsule Robot: A Cutting‐Edge Platform for Sampling, Diagnosis, and Therapy

Advanced Robotics Research, EarlyView.
Gut microbiota and biomarkers are linked to diseases like neurological disorders and metabolic syndromes. Ingestible capsule robots enable minimally invasive gut health assessment. This article proposes a promising direction for the advancement of capsule robots, integrating in situ sampling, real‐time diagnostics, and personalized therapy.
Xizong Chen, Libing Huang, Lei Ren, Miao Wang   +3 more
wiley   +1 more source