Results 131 to 140 of about 131,877 (321)

Isolation and biological characteristics analysis of a bacteriophage of Enterococcus faecalis

open access: yesZhongguo shipin weisheng zazhi
ObjectiveTo isolate and identify a bacteriophage of Enterococcus faecalis and to analyze its biological characteristics.MethodsThe host bacteria was isolated from the process of yak slaughtering and identified by 16S rRNA sequencing.
WANG Jinli   +5 more
doaj   +1 more source

Brief overview on Bacteriophage therapy; Alternative to Antibiotics [PDF]

open access: yesarXiv
The term bacteriophage means killer or eater of bacteria. They were initially discovered by F.W. Twort and later on, Felix d'Herelle unveiled them to the world in 1910. Phage therapy has arisen as a favorable option to conventional antibiotics by reducing the multinational problem of increasing antibacterial resistance.
arxiv  

Engineering and Structural Elucidation of a Sac7d‐Derived IgG Fc‐Specific Affitin and Its Application for the Light‐Controlled Affinity Purification of Antibodies

open access: yesChemBioChem, EarlyView.
An affitin derived from the Sac7d scaffold enables the light‐controlled affinity purification of antibodies under physiological conditions, thus overcoming limitations of protein A chromatography. X‐ray crystallographic analysis and affinity measurements reveal complex formation with Fc at the CH2/CH3 junction, similar to protein A/G and FnRn. Combined
Felix Veitl   +7 more
wiley   +1 more source

The Molecular Toolbox for Linkage Type‐Specific Analysis of Ubiquitin Signaling

open access: yesChemBioChem, EarlyView.
Ubiquitin modifications regulate virtually all aspects of eukaryotic cell biology through an array of polyubiquitin chain signals that adopt distinct structures, enabling the individual polyubiquitin linkages to mediate specific functions in cells.
Julian Koch   +3 more
wiley   +1 more source

Synthesis of β,β‐Dinaphthyl Amino Acids: Towards Molecular Gearing in Peptides and Mini‐Proteins

open access: yesChemistry – A European Journal, EarlyView.
Amino acids bearing two aromatic side chains are studied here for their ability to align in rotor‐like assemblies in a synthetic protein. Based on quantitative analysis of 1H NMR reference nuclei, we investigate a correlated molecular rotor‐type behavior whose dynamic nature stands in remarkable contrast to established systems in the field of molecular
Timo Zimmer   +2 more
wiley   +1 more source

Chemical Protein Engineering: Backbone Cyclization Rescues Folding of a 183‐Residue Truncated Domain of Malaria Parasite Protein PfAMA1

open access: yesChemistry – A European Journal, EarlyView.
We report the first chemical synthesis of a 183‐residue functional truncated cyclic PfAMA1 domain I protein using multi‐segment native chemical ligation and head‐to‐tail cyclization to introduce conformational constraints, thereby facilitating protein folding and providing novel strategies for miniature protein engineering.
Jamsad Mannuthodikayil   +4 more
wiley   +1 more source

Resistance, mechanism, and fitness cost of specific bacteriophages for Pseudomonas aeruginosa

open access: yesmSphere
The bacteriophage is an effective adjunct to existing antibiotic therapy; however, in the course of bacteriophage therapy, host bacteria will develop resistance to bacteriophages, thus affecting the efficacy.
Luozhu Feng   +9 more
doaj   +1 more source

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