Results 121 to 130 of about 246,265 (316)

Mesoporous Catalytic‐Adsorptive Nanoregulator Orchestrates Biofilm eDNA/LPS Disassembly and TLR9/TLR4 Immune Reprogramming to Resolve Diabetic Foot Infections

Advanced Science, EarlyView.
Chronic diabetic wounds are hindered by a “dual trap” of biofilm resistance and hyperinflammation. A mesoporous catalytic‐adsorptive nano‐regulator is developed to dismantle this barrier through simultaneous eDNA degradation and LPS sequestration. By silencing TLR4/9‐mediated signaling, the platform clears resilient pathogens and reprograms the immune ...
Junfeng Song, Yang Song, Xirui Huang, Xingjin Li, Lifei Gao, Yixiang Wang, Tianbao Zhu, Xiaomin Li, Shuai Wang, Tiancong Zhao, Dongyuan Zhao   +10 more
wiley   +1 more source

Function of bacteriophage orf recombinasesin genetic exchange [PDF]

, 2006
Recombination events in bacteriophages frequently occur by illegitimate exchange at short tracts of sequence homology, enabling these viruses to acquire novel genes and serve as vehicles for horizontal gene transfer.
Reed, Patricia
core  

Frequent Sweetened Beverage Consumption Is Associated With Accelerated Biological Aging: Evidence From a Population‐Based Study and Gut Microbiota Analysis

Advanced Science, EarlyView.
Frequent sweetened beverage consumption is associated with accelerated biological aging in a large Chinese population. Five gut microbial genera are consistently enriched in both frequent sweetened beverage consumers and individuals with accelerated aging and show significant mediating effects, suggesting a potential microbiota‐related pathway linking ...
Yuwei Shi, Xinmei Li, Yufan Hao, Qiaoyu Wu, Yuji Yu, Siyu Li, Nuo Xu, Yi‐Hsuan Wu, Eunhye Lee, Chi Chang, Emily Hu, Ying Lu, Elizabeth Delzell, Ann W. Hsing, Shankuan Zhu   +14 more
wiley   +1 more source

Flap endonuclease of bacteriophage T7: Possible roles in RNA primer removal, recombination and host DNA breakdown [PDF]

, 2014
Gene 6 protein of bacteriophage T7 has 5′-3′-exonuclease activity specific for duplex DNA. We have found that gene 6 protein also has flap endonuclease activity. The flap endonuclease activity is considerably weaker than the exonuclease activity.
Richardson, Charles, Tabor, Stanley, Mitsunobu, Hitoshi, Zhu, Bin, Lee, Seung-Joo   +4 more
core   +1 more source

Systematic Position Mapping of Split CRISPR‐Cas12a Activators Enables Highly Sensitive miRNA Detection and Cancer Cell Stratification

Advanced Science, EarlyView.
ABSTRACT Amplification‐free Cas12a diagnostics with split crRNA enable rapid and programmable target recognition, yet insufficient understanding of DNA activator architecture prevents predictable control over trans‐cleavage activity and sensitivity. Here we systematically map over 200 split DNA activator configurations by introducing nicks at every ...
Xiaoyan Tang, Zhe Li, Yuning Lu, Miao Ma, Zijian Mo, Jiajun Ke, Xinyu Luan, Tiangang Luan, Junqiu Zhai   +8 more
wiley   +1 more source

Bacteriophage effectiveness in hard surfaces decontamination [PDF]

, 2017
Objectives: Persistently contaminated hospital surfaces represent a reservoir of infectious pathogens, hence contributing to the development of healthcare associated infections (HAI), which are often sustained by antibiotic-resistant pathogens.
D’Accolti Maria, Piffanelli Micol, Mzia Kutateladze, Coccagna Maddalena, Mazzacane Sante, Caselli Elisabetta   +5 more
core  

Association of a bacteriophage with virulence in Vibrio harveyi [PDF]

, 2003
(First paragraph) The virulence of Vibrio harveyi, which is a serious pathogen of penaeids (Karunasagar, Pai, Malathi & Karunasagar 1994; Pizzuto & Hirst 1995; Alvarez, Austin, Alvarez & Reyes 1998) and finfish (Kraxberger-Beatty, McGarey ...
Rhodie, G A, Pride, A. C., Pride, A C, Austin, Brian, Rhodie, G. A., Austin, B.   +5 more
core   +1 more source

Bacterial pathogens in fish and aquaculture systems in Kenya

Academia Biology
The rising global demand for high-quality animal protein has driven the rapid expansion of aquaculture, which is now responsible for 51% of global fish production.
Ivy J. Mutai, Barack Nyanswi, Eric Omori Omwenga, Auleria Ajiambo Apopo, Irene Kokushubila Lweikiza, Victor Irungu Mwangi, Michael Mugo, Felix Mwai, Mary A. Opiyo, Zipporah Gichana, Justus Nyongesa Opondo, Jael Apondi Obiero, Tabitha Wangari Nyoike, Joseph Mwangi, Abraham Ochieng, Atunga Nyachieo   +15 more
doaj   +1 more source

A Comprehensive Microbial Gene Catalog of the Human Airway Microbiome Across Anatomical Sites and Geographic Regions

Advanced Science, EarlyView.
An integrated Human Airway Microbiome Gene Catalog (iHAMGC) is constructed from 12,273 metagenomic airway samples, providing a high‐resolution reference of respiratory microbial genes. The catalog enables systematic exploration of taxonomic and functional variation across airway niches and geographic regions, revealing site‐specific and region ...
Qing Zhang, Dashu Li, Bo Liu, Yue Zhang, Min Li, Ruochun Guo, Yawen Ni, Shibin Chen, Biao Ni, Lijie Qiu, Guorui Xing, He Dong, Qiulong Yan, Shenghui Li, Xiaohui Zou, Bin Cao   +15 more
wiley   +1 more source

The sim gene of Escherichia coli phage P1: nucleotide sequence and purification of the processed protein [PDF]

, 1990
Maillou J, Dreiseikelmann B. The sim gene of Escherichia coli phage P1: nucleotide sequence and purification of the processed protein. Virology. 1990;175(2):500-507.The sim gene of bacteriophage P1 causes exclusion of a superinfecting P1 phage.
Maillou, Julia, Dreiseikelmann, Brigitte
core   +2 more sources