Results 101 to 110 of about 285,810 (297)

Biofilm‐Binding Phages Enhance Biofilm Eradication by Synergistic Photothermal and Photodynamic Therapy

open access: yesAdvanced Science, EarlyView.
Engineered phage‐based trifunctional nanofibers are developed for synergistic biofilm eradication. Biofilm‐binding phages, armed with AuNPs and TCPP, serve as both warheads and scaffolds, endowing the phototherapy agents with biofilm‐anchoring ability. Upon light irradiation, AuNPs induce photothermal therapy, while TCPP generates 1O2 for photodynamic ...
Ying Cao   +9 more
wiley   +1 more source

Protecting Newborns from Multidrug-Resistant Infections: The Emerging Role of Bacteriophages

open access: yesViruses
Newborns may suffer from dangerous bacterial infections caused by life-threatening multi-drug resistant pathogens. Thus, despite bactericidal capabilities of antibiotics, microorganisms are known to circumvent this therapy, and a new, more effective type
Olaf Bajrak   +2 more
doaj   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

open access: yesAdvanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li   +7 more
wiley   +1 more source

Targeted bacteriophage T4 nanoparticles reverse HIV-1 latency in human T cell line models

open access: yesiScience
Summary: A major barrier for HIV-1 eradication is the latent virus reservoir containing stably integrated and silent proviruses in CD4+ T cells. Targeted reactivation and removal of this latent reservoir is a potential strategy for HIV-1 cure, but ...
Himanshu Batra   +12 more
doaj   +1 more source

Safety Studies of Pneumococcal Endolysins Cpl-1 and Pal

open access: yesViruses, 2018
Bacteriophage-derived endolysins have gained increasing attention as potent antimicrobial agents and numerous publications document the in vivo efficacy of these enzymes in various rodent models. However, little has been documented about their safety and
Marek Harhala   +15 more
doaj   +1 more source

Nanomaterials for Allergy Diagnosis and Treatment: Advances, Opportunities and Translational Challenges

open access: yesAdvanced Science, EarlyView.
Nanomaterials offer dual applications in allergy management. For diagnosis, nanomaterials enhance analytical sensitivity and improve detection in specific IgE and functional assays such as the basophil activation test (BAT). For allergen‐specific immunotherapy, nanomaterials enable allergen masking and controlled release, and effectively modulate the ...
Madiha Habib   +8 more
wiley   +1 more source

Method for bacteriophage delivery and amplification [PDF]

open access: yes, 2011
Methods of selecting wide host range bacteriophage capable of growing in a plurality of bacteria including pathogenic and non-pathogenic bacteria and bacteriophage selected by the methods are disclosed.
Nava, Gerardo   +7 more
core   +3 more sources

High-Throughput Bacteriophage Testing with Potency Determination: Validation of an Automated Pipetting and Phage Drop-Off Method

open access: yesBiomedicines
The development of bacteriophages (phages) as active pharmaceutical ingredients for the treatment of patients is on its way and regulatory agencies are calling for reliable methods to assess phage potency.
Nicolas Dufour   +2 more
doaj   +1 more source

Bacteriophage Therapy: Recent Developments and Applications of a Renaissance Weapon

open access: yes
The spreading antibiotic resistance of bacteria is one of the most important challenges of modern medicine, and a search for methods that could replace conventional treatments of bacterial infections is urgently needed.

core   +1 more source

Unique characteristics of novel RNA bacteriophage.

open access: yes, 2016
(A) Genome organizations of three novel RNA bacteriophage partial genomes compared to prototypical RNA bacteriophage. (B) EMS013 and (C) Streptomyces bacteriophage ϕ0 genome organizations.
Dan Barouch (2580349)   +4 more
core   +1 more source

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