Results 111 to 120 of about 246,265 (316)

Nanoscale bacteriophage biosensors beyond phage display [PDF]

, 2013
Jong-Wook Lee,1 Jangwon Song,1,2 Mintai P Hwang,1 Kwan Hyi Lee1,2 1Center for Biomaterials, Biomedical Research Institute, Korea Institute of Science and Technology, Seoul, Korea; 2Department of Biomedical Engineering, University of Science and ...
Hwang MP, Song J, Lee JW, Lee KH
core  

Microblasting Wound Dressings Mechanically Disrupt Polymicrobial Biofilms to Enhance Healing in Treatment‐Resistant Wounds

Advanced Science, EarlyView.
Treatment‐resistant wounds caused by polymicrobial biofilms are refractory to conventional therapies due to the dense extracellular matrices. We developed μBLAST, a microblasting wound dressing that combines MnO2‐doped biosilica and a H2O2‐releasing mesh to generate localized oxygen microbubbles that mechanically disrupt biofilms.
Yujin Ahn, Joo Hun Lee, Christian Hurd, Jiye Lee, Junggeon Park, Adam A. Markowicz, Zheyuan Zhang, Joanne Hwang, Guillermo L. Monroy, Simon A. Rogers, Woonggyu Jung, Stephen A. Boppart, Hyunjoon Kong   +12 more
wiley   +1 more source

EFFECTS OF BACTERIOPHAGE SUPPLEMENTED DIET ON INTESTINAL BENEFICIARY MICROFLORA AND PRODUCTIVE PERFORMANCE OF BROILER [PDF]

, 2022
A Thesis Submitted to the Department of Poultry Science Sher-e-Bangla Agricultural University, Dhaka In Partial fulfillment of the requirements for the degree of MASTER OF SCIENCE (MS) IN POULTRY SCIENCEThe Experiment was done to investigate the
NAIN, MD.ZULKAR
core  

Targeted bacteriophage T4 nanoparticles reverse HIV-1 latency in human T cell line models

iScience
Summary: A major barrier for HIV-1 eradication is the latent virus reservoir containing stably integrated and silent proviruses in CD4+ T cells. Targeted reactivation and removal of this latent reservoir is a potential strategy for HIV-1 cure, but ...
Himanshu Batra, Jingen Zhu, Swati Jain, Neeti Ananthaswamy, Marthandan Mahalingam, Pan Tao, Camille Lange, Shawn Hill, Chaojie Zhong, Mary F. Kearney, Haitao Hu, Frank Maldarelli, Venigalla B. Rao   +12 more
doaj   +1 more source

CREAT: A CRISPR‐Based Genome Trimming Strategy for Systematic Identification of Dispensable Regions and Rapid Genome Reduction

Advanced Science, EarlyView.
Current genome‐reduction methods work in a trial‐and‐error fashion, constituting a long‐standing bottleneck in the research. We developed CREAT (CRISPR‐based genome trimming with a multi‐homology‐arm template), a CRISPR‐based genetic approach that enables systematically classifying essential versus non‐essential genomic regions and subsequently ...
Guanhua Yuan, Zhe Gao, Yingxuan Qi, Yang Zhang, Xuhui Tian, Pengpeng Zhao, Xu Feng, Qunxin She   +7 more
wiley   +1 more source

High-Throughput Bacteriophage Testing with Potency Determination: Validation of an Automated Pipetting and Phage Drop-Off Method

Biomedicines
The development of bacteriophages (phages) as active pharmaceutical ingredients for the treatment of patients is on its way and regulatory agencies are calling for reliable methods to assess phage potency.
Nicolas Dufour, Raphaëlle Delattre, Laurent Debarbieux   +2 more
doaj   +1 more source

Safety Studies of Pneumococcal Endolysins Cpl-1 and Pal

Viruses, 2018
Bacteriophage-derived endolysins have gained increasing attention as potent antimicrobial agents and numerous publications document the in vivo efficacy of these enzymes in various rodent models. However, little has been documented about their safety and
Marek Harhala, Daniel C. Nelson, Paulina Miernikiewicz, Ryan D. Heselpoth, Beata Brzezicka, Joanna Majewska, Sara B. Linden, Xiaoran Shang, Aleksander Szymczak, Dorota Lecion, Karolina Marek-Bukowiec, Marlena Kłak, Bartosz Wojciechowicz, Karolina Lahutta, Andrzej Konieczny, Krystyna Dąbrowska   +15 more
doaj   +1 more source

Nanomaterials for Allergy Diagnosis and Treatment: Advances, Opportunities and Translational Challenges

Advanced Science, EarlyView.
Nanomaterials offer dual applications in allergy management. For diagnosis, nanomaterials enhance analytical sensitivity and improve detection in specific IgE and functional assays such as the basophil activation test (BAT). For allergen‐specific immunotherapy, nanomaterials enable allergen masking and controlled release, and effectively modulate the ...
Madiha Habib, Shan Jiang, Joyce ZX Lee, CW Lim, HL Yeung, Nicki YH Leung, Patrick SC Leung, Ting F Leung, Christine YY Wai   +8 more
wiley   +1 more source

Dynamics of DNA replication loops reveal temporal control of lagging-strand synthesis [PDF]

, 2009
In all organisms, the protein machinery responsible for the replication of DNA, the replisome, is faced with a directionality problem. The antiparallel nature of duplex DNA permits the leading-strand polymerase to advance in a continuous fashion, but ...
Richardson, Charles C.,, Takahashi, Masateru, Vanoijen, Antoine M., Hamdan, Samir M., Joseph J. Loparo, Loparo, Joseph J., Richardson, Charles C., Takahashi, Masateru,, Oijen, Antoine M. van, Oijen, Antoine M. van,, Loparo, Joseph J.,, Antoine M. van Oijen, Samir M. Hamdan, Masateru Takahashi, Hamdan, Samir M.,, Charles C. Richardson   +15 more
core   +1 more source

Perspectives of Phage–Eukaryotic Cell Interactions to Control Epstein–Barr Virus Infections

Frontiers in Microbiology, 2018
Recently, leading medical journals emphasized the importance of further studies on the potential application of bacterial viruses (phages) for the treatment of antibiotics-resistant infections outlining the present status of the therapy and perspectives ...
Andrzej Górski, Andrzej Górski, Andrzej Górski, Ryszard Międzybrodzki, Ryszard Międzybrodzki, Ryszard Międzybrodzki, Ewa Jończyk-Matysiak, Beata Weber-Dąbrowska, Beata Weber-Dąbrowska, Natalia Bagińska, Jan Borysowski   +10 more
doaj   +1 more source