Results 11 to 20 of about 441,842 (342)
Pharokka: a fast scalable bacteriophage annotation tool
Bioinform., 2022 Summary In recent years, there has been an increasing interest in bacteriophages, which has led to growing numbers of bacteriophage genomic sequences becoming available.
G. Bouras +5 more
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Nature Communications, 2022 A 30-year-old bombing victim with a fracture-related pandrug-resistant Klebsiella pneumoniae infection after long-term (>700 days) antibiotic therapy is treated with a pre-adapted bacteriophage along with meropenem and colistin, followed by ceftazidime ...
Anaïs Eskenazi +17 more
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Frontiers in Microbiology, 2023 Bacteriophages, the most abundant organisms on earth, have the potential to address the rise of multidrug-resistant bacteria resulting from the overuse of antibiotics. However, their high specificity and limited host range can hinder their effectiveness.
Huang-Jie Jia +5 more
semanticscholar +1 more source
Mechanisms and clinical importance of bacteriophage resistance
FEMS Microbiology Reviews, 2021 We are in the midst of a golden age of uncovering defense systems against bacteriophages. Apart from the fundamental interest in these defense systems, and revolutionary applications that have been derived from them (e.g.
Julia E. Egido +4 more
semanticscholar +1 more source
Bacteriophage treatment of disseminated cutaneous Mycobacterium chelonae infection
Nature Communications, 2022 Mycobacterium chelonae is a rare cause of chronic disseminated cutaneous infections in immunocompromised patients. Multidrug-resistant M. chelonae infections present a challenge for treatment, and prolonged antimicrobial courses lead to significant ...
J. Little +9 more
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From Host to Phage Metabolism: Hot Tales of Phage T4’s Takeover of E. coli
Viruses, 2018 The mechanisms by which bacteriophage T4 converts the metabolism of its E. coli host to one dedicated to progeny phage production was the subject of decades of intense research in many labs from the 1950s through the 1980s.
Elizabeth Kutter +5 more
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Staphylococcus aureus temperate bacteriophage: carriage and horizontal gene transfer is lineage associated. [PDF]
, 2012 Staphylococcus aureus is a major cause of human and animal infections. Bacteriophage are a class of mobile genetic element (MGE) that carry virulence genes and disseminate them horizontally, including Panton-Valentine leukocidin (PVL), the immune evasion
Lindsay, JA, McCarthy, AJ, Witney, AA
core +2 more sources
Frontiers in Cellular and Infection Microbiology, 2022 Staphylococcus aureus (S. aureus) is a common and virulent human pathogen causing several serious illnesses including skin abscesses, wound infections, endocarditis, osteomyelitis, pneumonia, and toxic shock syndrome. Antibiotics were first introduced in
Lucile Plumet +7 more
semanticscholar +1 more source
Real-Time qPCR as a Method for Detection of Antibody-Neutralized Phage Particles
Frontiers in Microbiology, 2017 The most common method for phage quantitation is the plaque assay, which relies on phage ability to infect bacteria. However, non-infective phage particles may preserve other biological properties; specifically, they may enter interactions with the ...
Anna Kłopot +11 more
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Phage Interactions with the Nervous System in Health and Disease
Cells, 2023 The central nervous system manages all of our activities (e.g., direct thinking and decision-making processes). It receives information from the environment and responds to environmental stimuli.
Adam Jędrusiak +4 more
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