Results 11 to 20 of about 249,047 (357)

Human β-Defensin 2 and Its Postulated Role in Modulation of the Immune Response

Cells, 2021
Studies described so far suggest that human β-defensin 2 is an important protein of innate immune response which provides protection for the human organism against invading pathogens of bacterial, viral, fungal, as well as parasitical origin. Its pivotal
Martyna Cieślik, Natalia Bagińska, Andrzej Górski, Ewa Jończyk-Matysiak   +3 more
doaj   +1 more source

The Role of Antibiotic Resistant A. baumannii in the Pathogenesis of Urinary Tract Infection and the Potential of Its Treatment with the Use of Bacteriophage Therapy

Antibiotics, 2021
Acinetobacter baumannii are bacteria that belong to the critical priority group due to their carbapenems and third generation cephalosporins resistance, which are last-chance antibiotics.
Natalia Bagińska, Martyna Cieślik, Andrzej Górski, Ewa Jończyk-Matysiak   +3 more
doaj   +1 more source

Biological Properties of 12 Newly Isolated Acinetobacter baumannii-Specific Bacteriophages

Viruses, 2023
Infections with the opportunistic Gram-negative bacterium Acinetobacter baumannii pose a serious threat today, which is aggravated by the growing problem of multi-drug resistance among bacteria, caused by the overuse of antibiotics.
Natalia Bagińska, Marek Adam Harhala, Martyna Cieślik, Filip Orwat, Beata Weber-Dąbrowska, Krystyna Dąbrowska, Andrzej Górski, Ewa Jończyk-Matysiak   +7 more
doaj   +1 more source

Investigating bacteriophages targeting the opportunistic pathogen Acinetobacter baumannii [PDF]

, 2020
The multi-drug resistance of the opportunistic pathogen Acinetobacter baumannii is of growing concern, with many clinical isolates proving to be resistant to last resort as well as front line antibiotic treatments.
Christie, Gabrielle S., Dowson, Christopher G., Leungtongkam, Udomluk, Millard, Andrew D., Moat, John, Sagona, Antonia P., Sitthisak, Sutthirat, Smith, Sophie, Styles, Kathryn, Thummeepak, Rapee, Wellington, Elizabeth M. H.   +10 more
core   +1 more source

Bacteriophages and antibiotic interactions in clinical practice: what we have learned so far

Journal of Biomedical Science, 2022
Bacteriophages (phages) may be used as an alternative to antibiotic therapy for combating infections caused by multidrug-resistant bacteria. In the last decades, there have been studies concerning the use of phages and antibiotics separately or in ...
Marzanna Łusiak-Szelachowska, Ryszard Międzybrodzki, Zuzanna Drulis-Kawa, Kathryn Cater, Petar Knežević, Cyprian Winogradow, Karolina Amaro, Ewa Jończyk-Matysiak, Beata Weber-Dąbrowska, Justyna Rękas, Andrzej Górski   +10 more
doaj   +1 more source

Breakthrough Solution for Antimicrobial Resistance Detection: Surface‐Enhanced Raman Spectroscopy‐based on Artificial Intelligence

Advanced Materials Interfaces, EarlyView., 2023
This review discusses the use of Surface‐Enhanced Raman Spectroscopy (SERS) combined with Artificial Intelligence (AI) for detecting antimicrobial resistance (AMR). Various SERS studies used with AI techniques, including machine learning and deep learning, are analyzed for their advantages and limitations.
Zakarya Al‐Shaebi, Munevver Akdeniz, Awel Olsido Ahmed, Mine Altunbek, Omer Aydin   +4 more
wiley   +1 more source

How Interest in Phages Has Bloomed into a Leading Medical Research Activity in Poland

Viruses, 2022
Poland has a leading position in phage therapy, as reflected by the number of patients treated and relevant publications in quality journals. The Institute of Immunology and Experimental Therapy of the Polish Academy of Sciences was established by Ludwik
Maciej Żaczek, Andrzej Górski, Andrzej Grzybowski, Edyta Pasternak, Beata Weber-Dąbrowska, Ryszard Międzybrodzki   +5 more
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Bacteriophage Assembly [PDF]

Viruses, 2011
Bacteriophages have been a model system to study assembly processes for over half a century. Formation of infectious phage particles involves specific protein-protein and protein-nucleic acid interactions, as well as large conformational changes of assembly precursors.
Anastasia A. Aksyuk, Michael G. Rossmann
openaire   +3 more sources

Immune Response to Therapeutic Staphylococcal Bacteriophages in Mammals: Kinetics of Induction, Immunogenic Structural Proteins, Natural and Induced Antibodies

Frontiers in Immunology, 2021
Bacteriophages are able to affect the human immune system. Phage-specific antibodies are considered as major factors shaping phage pharmacokinetics and bioavailability.
Zuzanna Kaźmierczak, Zuzanna Kaźmierczak, Joanna Majewska, Paulina Miernikiewicz, Ryszard Międzybrodzki, Ryszard Międzybrodzki, Sylwia Nowak, Marek Harhala, Dorota Lecion, Weronika Kęska, Barbara Owczarek, Jarosław Ciekot, Marek Drab, Paweł Kędzierski, Marta Mazurkiewicz-Kania, Andrzej Górski, Krystyna Dąbrowska   +16 more
doaj   +1 more source

Transduction of bacteriophage lambda by bacteriophage T1 [PDF]

Journal of Virology, 1979
When bacteriophage T1 was grown on bacteriophage lambda-lysogenic cells, phenotypically mixed particles were formed which had the serum sensitivity, host range, and density of T1 but which gave rise to lambda phage. T1 packaged lambda genomes more efficiently both when the length of the prophage was less than that of wild-type lambda and when the host ...
M M Bendig, H Drexler
openaire   +3 more sources