Real-Time qPCR as a Method for Detection of Antibody-Neutralized Phage Particles
The most common method for phage quantitation is the plaque assay, which relies on phage ability to infect bacteria. However, non-infective phage particles may preserve other biological properties; specifically, they may enter interactions with the ...
Anna Kłopot +11 more
doaj +1 more source
Phage Prevalence in the Human Urinary Tract—Current Knowledge and Therapeutic Implications
Recent metagenomic analyses imply an immense abundance of phages in the human body. Samples collected from different sites (lungs, skin, oral cavity, intestines, ascitic fluid, and urine) reveal a generally greater number of phage particles than that of ...
Maciej Żaczek +3 more
doaj +1 more source
Photocatalytic antimicrobial activity of thin surface films of TiO2, CuO and TiO2 /CuO dual layers on Escherichia coli and bacteriophage T4 [PDF]
TiO2 coated surfaces are increasingly studied for their ability to inactivate microorganisms. The activity of glass coated with thin films of TiO2, CuO and hybrid CuO/TiO2 prepared by atmospheric Chemical Vapour Deposition (Ap-CVD) and TiO2 prepared by a
Ditta, IB +7 more
core +2 more sources
Bacillus Phage vB_BtS_B83 Previously Designated as a Plasmid May Represent a New Siphoviridae Genus
The Bacillus cereus group of bacteria includes, inter alia, the species known to be associated with human diseases and food poisoning. Here, we describe the Bacillus phage vB_BtS_B83 (abbreviated as B83) infecting the species of this group.
Emma G. Piligrimova +3 more
doaj +1 more source
Phages as a Cohesive Prophylactic and Therapeutic Approach in Aquaculture Systems
Facing antibiotic resistance has provoked a continuously growing focus on phage therapy. Although the greatest emphasis has always been placed on phage treatment in humans, behind phage application lies a complex approach that can be usefully adopted by ...
Maciej Żaczek +2 more
doaj +1 more source
Fine Structure of Viral dsDNA Encapsidation [PDF]
In vivo configurations of dsDNA of bacteriophage viruses in a capsid are known to form hexagonal chromonic liquid crystal phases. This article studies the liquid crystal ordering of viral dsDNA in an icosahedral capsid, combining the chromonic model with
Arsuaga, Javier +4 more
core +3 more sources
Phage therapy: An alternative to antibiotics in the age of multi-drug resistance. [PDF]
The practice of phage therapy, which uses bacterial viruses (phages) to treat bacterial infections, has been around for almost a century. The universal decline in the effectiveness of antibiotics has generated renewed interest in revisiting this practice.
Koskella, Britt, Lin, Derek, Lin, Henry
core +1 more source
Do Anti-Phage Antibodies Persist after Phage Therapy? A Preliminary Report
Phages are immunogenic and may evoke an immune response following their administration. Consequently, patients undergoing phage therapy (PT) produce phage-neutralizing serum antibodies.
Marzanna Łusiak-Szelachowska +5 more
doaj +1 more source
Extensive horizontal gene transfer during Staphylococcus aureus co-colonization in vivo. [PDF]
Staphylococcus aureus is a commensal and major pathogen of humans and animals. Comparative genomics of S. aureus populations suggests that colonization of different host species is associated with carriage of mobile genetic elements (MGE), particularly ...
Gould, KA +5 more
core +2 more sources
A potential concern with bacteriophage (phage) therapeutics is a host-versus-phage response in which the immune system may neutralize or destroy phage particles and thus impair therapeutic efficacy, or a strong inflammatory response to repeated phage ...
Helen R. Freyberger +4 more
doaj +1 more source

