Results 21 to 30 of about 285,810 (297)
How Interest in Phages Has Bloomed into a Leading Medical Research Activity in Poland
Viruses, 2022 Poland has a leading position in phage therapy, as reflected by the number of patients treated and relevant publications in quality journals. The Institute of Immunology and Experimental Therapy of the Polish Academy of Sciences was established by Ludwik
Maciej Żaczek +5 more
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Bacteriophages and antibiotic interactions in clinical practice: what we have learned so far
Journal of Biomedical Science, 2022 Bacteriophages (phages) may be used as an alternative to antibiotic therapy for combating infections caused by multidrug-resistant bacteria. In the last decades, there have been studies concerning the use of phages and antibiotics separately or in ...
Marzanna Łusiak-Szelachowska +10 more
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Biological Properties of 12 Newly Isolated Acinetobacter baumannii-Specific Bacteriophages
Viruses, 2023 Infections with the opportunistic Gram-negative bacterium Acinetobacter baumannii pose a serious threat today, which is aggravated by the growing problem of multi-drug resistance among bacteria, caused by the overuse of antibiotics.
Natalia Bagińska +7 more
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From Host to Phage Metabolism: Hot Tales of Phage T4’s Takeover of E. coli
Viruses, 2018 The mechanisms by which bacteriophage T4 converts the metabolism of its E. coli host to one dedicated to progeny phage production was the subject of decades of intense research in many labs from the 1950s through the 1980s.
Elizabeth Kutter +5 more
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Frontiers in Immunology, 2021 Bacteriophages are able to affect the human immune system. Phage-specific antibodies are considered as major factors shaping phage pharmacokinetics and bioavailability.
Zuzanna Kaźmierczak +16 more
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Bacteriophage translocation [PDF]
FEMS Immunology & Medical Microbiology, 2006 The occurrence of phages in the human body, especially in the gastrointestinal tract, raises the question of their potential role in the physiology and pathology of this system. Especially important is the issue of whether phages can pass the intestinal wall and migrate to lymph, peripheral blood, and internal organs and, if so, the effects such a ...
Andrzej Górski +5 more
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The superimmunity gene sim of bacteriophage P1 causes superinfection exclusion [PDF]
, 1989 Kliem M, Dreiseikelmann B. The superimmunity gene sim of bacteriophage P1 causes superinfection exclusion. Virology. 1989;171(2):350-355.Previous work has shown that the sim gene of bacteriophage P1, if cloned into a multicopy vector, confers immunity ...
Dreiseikelmann, Brigitte, Kliem, Manfred
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Real-Time qPCR as a Method for Detection of Antibody-Neutralized Phage Particles
Frontiers in Microbiology, 2017 The most common method for phage quantitation is the plaque assay, which relies on phage ability to infect bacteria. However, non-infective phage particles may preserve other biological properties; specifically, they may enter interactions with the ...
Anna Kłopot +11 more
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Staphylococcus aureus temperate bacteriophage: carriage and horizontal gene transfer is lineage associated. [PDF]
, 2012 Staphylococcus aureus is a major cause of human and animal infections. Bacteriophage are a class of mobile genetic element (MGE) that carry virulence genes and disseminate them horizontally, including Panton-Valentine leukocidin (PVL), the immune evasion
McCarthy, AJ +8 more
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Phage Prevalence in the Human Urinary Tract—Current Knowledge and Therapeutic Implications
Microorganisms, 2020 Recent metagenomic analyses imply an immense abundance of phages in the human body. Samples collected from different sites (lungs, skin, oral cavity, intestines, ascitic fluid, and urine) reveal a generally greater number of phage particles than that of ...
Maciej Żaczek +3 more
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