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Bacteriophages and antibiotic interactions in clinical practice: what we have learned so far
Journal of Biomedical Science, 2022 Bacteriophages (phages) may be used as an alternative to antibiotic therapy for combating infections caused by multidrug-resistant bacteria. In the last decades, there have been studies concerning the use of phages and antibiotics separately or in ...
Marzanna Łusiak-Szelachowska +10 more
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Biological Properties of 12 Newly Isolated Acinetobacter baumannii-Specific Bacteriophages
Viruses, 2023 Infections with the opportunistic Gram-negative bacterium Acinetobacter baumannii pose a serious threat today, which is aggravated by the growing problem of multi-drug resistance among bacteria, caused by the overuse of antibiotics.
Natalia Bagińska +7 more
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Frontiers in Immunology, 2021 Bacteriophages are able to affect the human immune system. Phage-specific antibodies are considered as major factors shaping phage pharmacokinetics and bioavailability.
Zuzanna Kaźmierczak +16 more
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Bacteriophage translocation [PDF]
FEMS Immunology & Medical Microbiology, 2006 The occurrence of phages in the human body, especially in the gastrointestinal tract, raises the question of their potential role in the physiology and pathology of this system. Especially important is the issue of whether phages can pass the intestinal wall and migrate to lymph, peripheral blood, and internal organs and, if so, the effects such a ...
Andrzej Górski +5 more
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From Host to Phage Metabolism: Hot Tales of Phage T4’s Takeover of E. coli
Viruses, 2018 The mechanisms by which bacteriophage T4 converts the metabolism of its E. coli host to one dedicated to progeny phage production was the subject of decades of intense research in many labs from the 1950s through the 1980s.
Elizabeth Kutter +5 more
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Real-Time qPCR as a Method for Detection of Antibody-Neutralized Phage Particles
Frontiers in Microbiology, 2017 The most common method for phage quantitation is the plaque assay, which relies on phage ability to infect bacteria. However, non-infective phage particles may preserve other biological properties; specifically, they may enter interactions with the ...
Anna Kłopot +11 more
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Phage Prevalence in the Human Urinary Tract—Current Knowledge and Therapeutic Implications
Microorganisms, 2020 Recent metagenomic analyses imply an immense abundance of phages in the human body. Samples collected from different sites (lungs, skin, oral cavity, intestines, ascitic fluid, and urine) reveal a generally greater number of phage particles than that of ...
Maciej Żaczek +3 more
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Bacillus Phage vB_BtS_B83 Previously Designated as a Plasmid May Represent a New Siphoviridae Genus
Viruses, 2019 The Bacillus cereus group of bacteria includes, inter alia, the species known to be associated with human diseases and food poisoning. Here, we describe the Bacillus phage vB_BtS_B83 (abbreviated as B83) infecting the species of this group.
Emma G. Piligrimova +3 more
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Phages as a Cohesive Prophylactic and Therapeutic Approach in Aquaculture Systems
Antibiotics, 2020 Facing antibiotic resistance has provoked a continuously growing focus on phage therapy. Although the greatest emphasis has always been placed on phage treatment in humans, behind phage application lies a complex approach that can be usefully adopted by ...
Maciej Żaczek +2 more
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Phage Interactions with the Nervous System in Health and Disease
Cells, 2023 The central nervous system manages all of our activities (e.g., direct thinking and decision-making processes). It receives information from the environment and responds to environmental stimuli.
Adam Jędrusiak +4 more
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