Results 21 to 30 of about 246,265 (316)

Biological Properties of 12 Newly Isolated Acinetobacter baumannii-Specific Bacteriophages

open access: yesViruses, 2023
Infections with the opportunistic Gram-negative bacterium Acinetobacter baumannii pose a serious threat today, which is aggravated by the growing problem of multi-drug resistance among bacteria, caused by the overuse of antibiotics.
Natalia Bagińska   +7 more
doaj   +1 more source

Bacteriophage Therapy [PDF]

open access: yesAnnual Review of Microbiology, 2001
▪ Abstract  In 1917, bacteriophages were recognized as epizootic infections of bacteria and were almost immediately deployed for antibacterial therapy and prophylaxis. The early trials of bacteriophage therapy for infectious diseases were confounded, however, because the biological nature of bacteriophage was poorly understood.
A, Sulakvelidze   +2 more
openaire   +4 more sources

Immune Response to Therapeutic Staphylococcal Bacteriophages in Mammals: Kinetics of Induction, Immunogenic Structural Proteins, Natural and Induced Antibodies

open access: yesFrontiers in Immunology, 2021
Bacteriophages are able to affect the human immune system. Phage-specific antibodies are considered as major factors shaping phage pharmacokinetics and bioavailability.
Zuzanna Kaźmierczak   +16 more
doaj   +1 more source

From Host to Phage Metabolism: Hot Tales of Phage T4’s Takeover of E. coli

open access: yesViruses, 2018
The mechanisms by which bacteriophage T4 converts the metabolism of its E. coli host to one dedicated to progeny phage production was the subject of decades of intense research in many labs from the 1950s through the 1980s.
Elizabeth Kutter   +5 more
doaj   +1 more source

Bacteriophages and their genomes [PDF]

open access: yesCurrent Opinion in Virology, 2011
Bacteriophages occupy a unique position in biology, representing an absolute majority of all organisms in the biosphere. Because their genomes are relatively small, elucidating the genetic diversity of the phage population, deciphering their origins, and identifying the evolutionary mechanisms that shape the population would seem readily feasible.
Graham F, Hatfull, Roger W, Hendrix
openaire   +2 more sources

Real-Time qPCR as a Method for Detection of Antibody-Neutralized Phage Particles

open access: yesFrontiers in Microbiology, 2017
The most common method for phage quantitation is the plaque assay, which relies on phage ability to infect bacteria. However, non-infective phage particles may preserve other biological properties; specifically, they may enter interactions with the ...
Anna Kłopot   +11 more
doaj   +1 more source

Phage Prevalence in the Human Urinary Tract—Current Knowledge and Therapeutic Implications

open access: yesMicroorganisms, 2020
Recent metagenomic analyses imply an immense abundance of phages in the human body. Samples collected from different sites (lungs, skin, oral cavity, intestines, ascitic fluid, and urine) reveal a generally greater number of phage particles than that of ...
Maciej Żaczek   +3 more
doaj   +1 more source

The superimmunity gene sim of bacteriophage P1 causes superinfection exclusion [PDF]

open access: yes, 1989
Kliem M, Dreiseikelmann B. The superimmunity gene sim of bacteriophage P1 causes superinfection exclusion. Virology. 1989;171(2):350-355.Previous work has shown that the sim gene of bacteriophage P1, if cloned into a multicopy vector, confers immunity ...
Dreiseikelmann, Brigitte, Kliem, Manfred
core   +2 more sources

Phage Interactions with the Nervous System in Health and Disease

open access: yesCells, 2023
The central nervous system manages all of our activities (e.g., direct thinking and decision-making processes). It receives information from the environment and responds to environmental stimuli.
Adam Jędrusiak   +4 more
doaj   +1 more source

Cloning, sequencing, and overexpression of gene 16 of salmonella bacteriophage P22 [PDF]

open access: yes, 1992
Umlauf B, Dreiseikelmann B. Cloning, sequencing, and overexpression of gene 16 of salmonella bacteriophage P22. Virology. 1992;188(2):495-501.It has been suggested that gene product 16 of bacteriophage P22 forms a pore for DNA transfer and/or that it ...
Dreiseikelmann, Brigitte   +1 more
core   +2 more sources

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