Results 21 to 30 of about 355,018 (412)

Transduction of bacteriophage lambda by bacteriophage T1 [PDF]

open access: yesJournal of Virology, 1979
When bacteriophage T1 was grown on bacteriophage lambda-lysogenic cells, phenotypically mixed particles were formed which had the serum sensitivity, host range, and density of T1 but which gave rise to lambda phage. T1 packaged lambda genomes more efficiently both when the length of the prophage was less than that of wild-type lambda and when the host ...
H, Drexler, J R, Christensen
openaire   +2 more sources

Social Bacteriophages [PDF]

open access: yesMicroorganisms, 2020
Despite their simplicity, viruses can display social-like interactions such as cooperation, communication, and cheating. Focusing on bacteriophages, here we review features including viral product sharing, cooperative evasion of antiviral defenses, prudent host exploitation, superinfection exclusion, and inter-phage peptide-mediated signaling. We argue
Pilar Domingo-Calap   +2 more
openaire   +4 more sources

How Interest in Phages Has Bloomed into a Leading Medical Research Activity in Poland

open access: yesViruses, 2022
Poland has a leading position in phage therapy, as reflected by the number of patients treated and relevant publications in quality journals. The Institute of Immunology and Experimental Therapy of the Polish Academy of Sciences was established by Ludwik
Maciej Żaczek   +5 more
doaj   +1 more source

Bacteriophages and antibiotic interactions in clinical practice: what we have learned so far

open access: yesJournal of Biomedical Science, 2022
Bacteriophages (phages) may be used as an alternative to antibiotic therapy for combating infections caused by multidrug-resistant bacteria. In the last decades, there have been studies concerning the use of phages and antibiotics separately or in ...
Marzanna Łusiak-Szelachowska   +10 more
doaj   +1 more source

Bacteriophage Therapy [PDF]

open access: yesAnnual Review of Microbiology, 2001
▪ Abstract  In 1917, bacteriophages were recognized as epizootic infections of bacteria and were almost immediately deployed for antibacterial therapy and prophylaxis. The early trials of bacteriophage therapy for infectious diseases were confounded, however, because the biological nature of bacteriophage was poorly understood.
A, Sulakvelidze   +2 more
openaire   +4 more sources

Bacteriophage-resistant Acinetobacter baumannii are resensitized to antimicrobials

open access: yesNature Microbiology, 2021
We characterized two bacteriophages, ΦFG02 and ΦCO01, against clinical isolates of Acinetobacter baumannii and established that the bacterial capsule is the receptor for these phages.
F. G. Gordillo Altamirano   +14 more
semanticscholar   +1 more source

Immune Response to Therapeutic Staphylococcal Bacteriophages in Mammals: Kinetics of Induction, Immunogenic Structural Proteins, Natural and Induced Antibodies

open access: yesFrontiers in Immunology, 2021
Bacteriophages are able to affect the human immune system. Phage-specific antibodies are considered as major factors shaping phage pharmacokinetics and bioavailability.
Zuzanna Kaźmierczak   +16 more
doaj   +1 more source

Massive expansion of human gut bacteriophage diversity

open access: yesbioRxiv, 2020
Bacteriophages drive evolutionary change in bacterial communities by creating gene flow networks that fuel ecological adaptions. However, the extent of viral diversity and prevalence in the human gut remains largely unknown.
Luis F. Camarillo-Guerrero   +4 more
semanticscholar   +1 more source

From Host to Phage Metabolism: Hot Tales of Phage T4’s Takeover of E. coli

open access: yesViruses, 2018
The mechanisms by which bacteriophage T4 converts the metabolism of its E. coli host to one dedicated to progeny phage production was the subject of decades of intense research in many labs from the 1950s through the 1980s.
Elizabeth Kutter   +5 more
doaj   +1 more source

Bacteriophages and their genomes [PDF]

open access: yesCurrent Opinion in Virology, 2011
Bacteriophages occupy a unique position in biology, representing an absolute majority of all organisms in the biosphere. Because their genomes are relatively small, elucidating the genetic diversity of the phage population, deciphering their origins, and identifying the evolutionary mechanisms that shape the population would seem readily feasible.
Graham F, Hatfull, Roger W, Hendrix
openaire   +2 more sources

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